Methods
Seventy women with a positive nucleic acid amplification test (NAAT) for Chlamydia infection were enrolled: 34 pregnant and 36 non-pregnant women. At enrollment, women were screened and treated for additional vaginal and cervical infection, including bacterial vaginosis (BV), Trichomonas vaginalis (TV) and Neisseria gonorrhoeae (GC). All subjects received azithromycin 1000 mg by mouth for Chlamydia infection. Following treatment for Chlamydia and any additional infections, women returned at weekly intervals for Chlamydia tractomatis NAAT until a negative test of cure was documented. Subjects were provided condoms and asked to report sexual activity and condom use at each follow up visit. Subjects completed the study once a negative test of cure was documented. A survival analysis of the mean time in days to a negative test of cure was compared between groups.
Methods
Seventy women with a positive nucleic acid amplification test (NAAT) for Chlamydia infection were enrolled: 34 pregnant and 36 non-pregnant women. At enrollment, women were screened and treated for additional vaginal and cervical infection, including bacterial vaginosis (BV), Trichomonas vaginalis (TV) and Neisseria gonorrhoeae (GC). All subjects received azithromycin 1000 mg by mouth for Chlamydia infection. Following treatment for Chlamydia and any additional infections, women returned at weekly intervals for Chlamydia tractomatis NAAT until a negative test of cure was documented. Subjects were provided condoms and asked to report sexual activity and condom use at each follow up visit. Subjects completed the study once a negative test of cure was documented. A survival analysis of the mean time in days to a negative test of cure was compared between groups.
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