Neurologic Formulas and Parameters




INTRACRANIAL PRESSURE



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  • Normal 0 to 20 mmHg





CEREBRAL PERFUSION PRESSURE (CPP)



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Formula: CPP = Mean Arterial Pressure (MAP) − Intracranial Pressure (ICP)




  • Infants: 40 mmHg



  • Adults: 65 mmHg




    • Changes throughout development: parallels changes in systemic blood pressure (BP); increases gradually throughout development to adult levels.



    • Consider patient’s baseline BP: Baseline MAP should be considered when considering therapeutic target for CPP in setting of acute neurologic injury. A patient with baseline hypertension will need blood pressure supported to a level that approximates their baseline physiology.



    • In adults poor outcomes are associated with sustained CPP <40 mmHg.






CEREBRAL BLOOD FLOW (CBF)



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  • Infants: 40 mL/100 g/min



  • Children (4 years): 100 mL/100 g/min



  • Children (9 years): 50 to 70 mL/100 g/min



  • Adults: 50 mL/100 g/min


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Jan 14, 2019 | Posted by in PEDIATRICS | Comments Off on Neurologic Formulas and Parameters
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