Middle Ear Lesion
H. Ric Harnsberger, MD
DIFFERENTIAL DIAGNOSIS
Common
Chronic Otitis Media (COM)
Acquired Cholesteatoma, Pars Flaccida
Congenital Cholesteatoma, Middle Ear
Less Common
Acute Otomastoiditis (AOM) with Coalescent Otomastoiditis
Acquired Cholesteatoma, Pars Tensa
Cholesterol Granuloma, Middle Ear
COM with Tympanosclerosis
COM with Ossicular Erosions
Rare but Important
Rhabdomyosarcoma, Middle Ear
Langerhans Histiocytosis, T-Bone
Dehiscent Jugular Bulb
Aberrant Internal Carotid Artery
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
Otoscopic findings often provide critical clues to precise diagnosis of middle ear lesion in child
Presence or absence of tympanic membrane (TM) rupture important
Pars tensa &/or flaccida acquired cholesteatoma has ruptured TM
Color and location of retrotympanic mass may be key to imaging diagnosis
Helpful Clues for Common Diagnoses
Chronic Otitis Media (COM)
Otoscopy: Thickened tympanic membrane
Bone CT: Linear, sporadic middle ear-mastoid tissue; mastoid air cells may be underpneumatized
Acquired Cholesteatoma, Pars Flaccida
Otoscopy: Rupture or retraction pocket affecting pars flaccida portion of tympanic membrane
Bone CT: Nondependent soft tissue filling Prussak space with ossicle and/or bony wall erosions
Possible complications: Tegmen tympani, lateral semicircular canal, facial nerve canal dehiscence
Congenital Cholesteatoma, Middle Ear
Otoscopy: White mass behind intact TM
Bone CT: Smooth, well-circumscribed soft tissue mass filling middle ear; often medial to ossicle chain
Ossicle erosion often absent
Mastoid pneumatization often normal
Helpful Clues for Less Common Diagnoses
Acute Otomastoiditis (AOM) with Coalescent Otomastoiditis
Otoscopy: Bulging, inflamed tympanic membrane
Bone CT: Complete middle ear-mastoid opacification with mastoid trabecular breakdown
Hint: Look on soft tissue windows for adjacent postauricular abscess or epidural abscess
Acquired Cholesteatoma, Pars Tensa
Otoscopy: Ruptured pars tensa portion of TM
Bone CT: Meso- and hypotympanic soft tissue mass often extending posteriorly or medially
Cholesterol Granuloma, Middle Ear
Otoscopy: Blue-black material behind intact TM
Bone CT: Middle ear soft tissue mass with minimal bony erosion
MR: High T1 and high T2 signal of material in middle ear (ME)
Hint: Old blood in cholesterol granuloma creates T1 shortening
COM with Tympanosclerosis
Otoscopy: Opaque, calcified tympanic membrane
Bone CT: Postinflammatory calcifications may affect ossicles, ligaments or TM
COM with Ossicular Erosions
Otoscopy: Thickened TM without normal ossicle impressions
Bone CT: Linear middle ear and mastoid air cell opacifications with partial ossicle absence
Long process of incus-lenticular process and stapes hub most commonly affected
Helpful Clues for Rare Diagnoses
Rhabdomyosarcoma, Middle Ear
Otoscopy: EAC “polyp”
Bone CT: Destructive middle ear mass that often affects EAC, ossicles, surrounding bones, overlying dura
Langerhans Histiocytosis, T-bone
Otoscopy: Postauricular mass common
Bone CT: Unilateral or bilateral (30%) destructive T-bone lesions affecting middle ear secondarily
Mastoid air cell more commonly affected than petrous apex or inner ear
Dehiscent Jugular Bulb
Otoscopy: Blue lesion behind posteroinferior quadrant of TM
Bone CT: Dehiscent sigmoid plate projects jugular bulb into posteroinferior middle ear cavity
Aberrant Internal Carotid Artery
Otoscopy: Reddish mass passes across inferior half of TM
Bone CT: Tubular lesion passes into posteroinferior middle ear cavity through enlarged inferior tympanic canaliculus
Aberrant ICA passes out of middle ear cavity anteroinferiorly by accessing posterolateral margin of horizontal petrous internal carotid artery
Other Essential Information
Best imaging tool for middle ear lesion in child: T-bone CT without contrast
Thin-section, fat-saturated MR only used for further evaluation of larger lesions involving inner ear, floor middle cranial fossa or sigmoid sinus-posterior fossa
Tumor or tumor-like lesions to consider in middle ear of child
Rhabdomyosarcoma and Langerhans cell histiocytosis
May be difficult to tell these 2 lesions apart
Rhabdomyosarcoma, Middle Ear
Unilateral; centered in middle ear cavity; may present with EAC “polyp”
Langerhans Histiocytosis, T-Bone
May be bilateral; centered around middle ear cavity, especially in mastoid; may present as postauricular mass
Alternative Differential Approaches
Otoscopic exam findings vs. diagnosis
White middle ear (ME) mass with associated ruptured or retracted pars flaccida TMStay updated, free articles. Join our Telegram channel
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