Lateral Ventricular Mass



Lateral Ventricular Mass


Bernadette L. Koch, MD



DIFFERENTIAL DIAGNOSIS


Common



  • Choroid Plexus Cyst


  • Intraventricular Hemorrhage (IVH)


Less Common



  • Subependymal Giant Cell Astrocytoma


  • Ependymal Cyst


  • Choroid Plexus Papilloma


Rare but Important



  • Choroid Plexus Carcinoma


  • Meningioma


  • Langerhans Cell Histiocytosis


  • Central Neurocytoma


  • Subependymoma


  • Ependymoma


ESSENTIAL INFORMATION


Helpful Clues for Common Diagnoses



  • Choroid Plexus Cyst



    • Key facts



      • Most common intraventricular mass in children and adults


      • Any age; adults > > children


      • Frequently bilateral


      • Usually incidental; rarely large enough to image obstructive hydrocephalus


      • Lateral ventricle > > > 3rd ventricle


    • Imaging findings



      • Cyst within or attached to choroid plexus


      • CE cyst wall and surrounding choroid


      • Hyperintense FLAIR and DWI common


      • ± irregular peripheral calcifications


      • Xanthogranuloma = laden degenerative cyst; more common in adults


  • Intraventricular Hemorrhage (IVH)



    • Key facts



      • 2° to germinal matrix hemorrhage, trauma, tumor, or vascular malformation


    • Imaging findings



      • Intraventricular hemorrhage initially hyperechoic and hyperdense


      • ± dependent fluid-fluid level


      • ± clotted blood adherent to choroid plexus


      • May → ventriculitis &/or hydrocephalus


      • Post-traumatic IVH: Frequently with SAH, and usually sequelae of severe injury


Helpful Clues for Less Common Diagnoses



  • Subependymal Giant Cell Astrocytoma



    • Key facts



      • Present in 15% of patients with tuberous sclerosis complex


    • Imaging findings



      • Heterogeneously enhancing mass near foramen of Monro


      • ± calcifications


      • + intraparenchymal hamartomas


      • ± obstructive hydrocephalus


      • ± globe hamartomas


      • Enhancement alone does not allow discrimination from hamartoma


      • Growth suggests subependymal giant cell astrocytoma rather than hamartoma


      • MRS: Less than expected ↓ NAA due to neuronal elements in tumor


  • Ependymal Cyst



    • Key facts



      • Synonym: Neuroepithelial cyst


      • Congenital, benign ependymal-lined cyst


      • Intraventricular, central WM of temporoparietal and frontal lobes, subarachnoid space, mesencephalon


    • Imaging findings



      • Lateral ventricle > > > 3rd and 4th ventricle


      • Nonenhancing, thin-walled cyst


      • Round or multiseptated


      • Similar to CSF on all imaging


      • ± hyperintensity on T2WI and FLAIR


  • Choroid Plexus Papilloma



    • Key facts



      • Lateral > 3rd and 4th ventricle in children


      • 4th ventricle most common site in adults


      • Usually < 1 year of age at diagnosis


      • Males > > > females


      • Rarely bilateral


      • Usually present with hydrocephalus secondary to obstruction, CSF overproduction by tumor or hemorrhage image impaired CSF resorption


      • Differentiation from choroid plexus carcinoma is histologic, not radiologic


    • Imaging findings



      • CT: Lobulated, isodense, or hyperdense


      • ± punctate foci calcification


      • T2 hypointense center


      • Intense contrast enhancement



      • MRS: Absent NAA and Cr/PhCr peak, increased lactate secondary to necrosis, not necessarily more aggressive


      • ± CSF metastases


Helpful Clues for Rare Diagnoses

Aug 10, 2016 | Posted by in PEDIATRICS | Comments Off on Lateral Ventricular Mass

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