Methods
The PPROM Study team conducted a prospective study of women presenting to a Canadian tertiary care center with PPROM between 24+0 and 33+6 weeks gestational age. Ruptured membranes were confirmed clinically and inclusion criteria included capacity to provide informed consent in English, singleton gestation, no iatrogenic PPROM and no known fetal anomalies. Cases of PPROM were managed according to local standard of care practices. Intake physical exam included vaginal and cervical swabs to rule out genital infection and screen for Group B streptococcus colonization. Demographic and clinical characteristics were collected from patient charts. Chorioamnionitis was identified both clinically and histopathologically. Both absolute and proportional pregnancy latency were calculated for each case.
Methods
The PPROM Study team conducted a prospective study of women presenting to a Canadian tertiary care center with PPROM between 24+0 and 33+6 weeks gestational age. Ruptured membranes were confirmed clinically and inclusion criteria included capacity to provide informed consent in English, singleton gestation, no iatrogenic PPROM and no known fetal anomalies. Cases of PPROM were managed according to local standard of care practices. Intake physical exam included vaginal and cervical swabs to rule out genital infection and screen for Group B streptococcus colonization. Demographic and clinical characteristics were collected from patient charts. Chorioamnionitis was identified both clinically and histopathologically. Both absolute and proportional pregnancy latency were calculated for each case.
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