39: Prognosis after preterm premature rupture of membranes (PPROM) for women with history of genital and non-genital infections




Objectives


Our intention was to query whether recent infection or antibiotic use influenced latency and risk of chorioamnionitis after preterm premature rupture of membranes.




Methods


The PPROM Study team conducted a prospective study of women presenting to a Canadian tertiary care center with PPROM between 24+0 and 33+6 weeks gestational age. Ruptured membranes were confirmed clinically and inclusion criteria included capacity to provide informed consent in English, singleton gestation, no iatrogenic PPROM and no known fetal anomalies. Cases of PPROM were managed according to local standard of care practices. Intake physical exam included vaginal and cervical swabs to rule out genital infection and screen for Group B streptococcus colonization. Demographic and clinical characteristics were collected from patient charts. Chorioamnionitis was identified both clinically and histopathologically. Both absolute and proportional pregnancy latency were calculated for each case.




Methods


The PPROM Study team conducted a prospective study of women presenting to a Canadian tertiary care center with PPROM between 24+0 and 33+6 weeks gestational age. Ruptured membranes were confirmed clinically and inclusion criteria included capacity to provide informed consent in English, singleton gestation, no iatrogenic PPROM and no known fetal anomalies. Cases of PPROM were managed according to local standard of care practices. Intake physical exam included vaginal and cervical swabs to rule out genital infection and screen for Group B streptococcus colonization. Demographic and clinical characteristics were collected from patient charts. Chorioamnionitis was identified both clinically and histopathologically. Both absolute and proportional pregnancy latency were calculated for each case.

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May 2, 2017 | Posted by in GYNECOLOGY | Comments Off on 39: Prognosis after preterm premature rupture of membranes (PPROM) for women with history of genital and non-genital infections
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