34: Incidence and predictors of re-infection with trichomoniasis based on nucleic acid amplification testing results in HIV-infected patients




Objectives


Trichomonas vaginalis, the most common non-viral sexually transmitted infection, may facilitate the transmission of HIV. The objective of this study was to determine the incidence and predictors of T. vaginalis re-infection among a cohort of HIV-infected patients.




Methods


This was a retrospective follow-up analysis of female and male HIV-infected patients at a large urban HIV clinic with at least one diagnosis of T. vaginalis based on nucleic acid amplification testing (NAAT) results. Re-infection was defined as having at least 2 positive T. vaginalis testing results during the study timeframe (August 2014-March 2016), including a positive result after metronidazole was prescribed for a first episode of infection and/or a positive result after an interval negative result following a first episode of infection. Time to first episode of T. vaginalis re-infection was evaluated using Kaplan-Meier survival curves while the association of various predictors was evaluated by univariate and multivariable Cox proportional hazards analyses.




Methods


This was a retrospective follow-up analysis of female and male HIV-infected patients at a large urban HIV clinic with at least one diagnosis of T. vaginalis based on nucleic acid amplification testing (NAAT) results. Re-infection was defined as having at least 2 positive T. vaginalis testing results during the study timeframe (August 2014-March 2016), including a positive result after metronidazole was prescribed for a first episode of infection and/or a positive result after an interval negative result following a first episode of infection. Time to first episode of T. vaginalis re-infection was evaluated using Kaplan-Meier survival curves while the association of various predictors was evaluated by univariate and multivariable Cox proportional hazards analyses.

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May 2, 2017 | Posted by in GYNECOLOGY | Comments Off on 34: Incidence and predictors of re-infection with trichomoniasis based on nucleic acid amplification testing results in HIV-infected patients

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