19: Extended spectrum beta-lactamase urinary tract infections during pregnancy

Objectives

Extended spectrum beta-lactamases (ESBLs) are enzymes produced by gram-negative bacilli that result in resistance against most antibiotics. We sought to evaluate the epidemiology and impact of ESBL urinary tract infections (UTIs) during pregnancy.

Methods

We performed a case control study comparing outcomes in pregnant women with optimally treated ESBL UTIs, sub-optimally treated ESBL UTIs, and non-ESBL UTIs from 2012-2014. Sub-optimal treatment was defined as treatment without carbapenems or post-treatment negative urine culture. For those with ESBL UTIs, we identified antecedent infections, prior antibiotic use, and the treatment course.

Methods

We performed a case control study comparing outcomes in pregnant women with optimally treated ESBL UTIs, sub-optimally treated ESBL UTIs, and non-ESBL UTIs from 2012-2014. Sub-optimal treatment was defined as treatment without carbapenems or post-treatment negative urine culture. For those with ESBL UTIs, we identified antecedent infections, prior antibiotic use, and the treatment course.

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May 2, 2017 | Posted by in GYNECOLOGY | Comments Off on 19: Extended spectrum beta-lactamase urinary tract infections during pregnancy

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