Unilateral Hyperlucent Lung
Daniel J. Podberesky, MD
DIFFERENTIAL DIAGNOSIS
Common
Endobronchial Obstruction/Foreign Body
Asthma
Pneumothorax
Less Common
Swyer-James Syndrome
Extrinsic Airway Compression by Mass Lesion
Vascular Ring/Sling
Scimitar Syndrome
Bulla
Rare but Important
Pulmonary Agenesis/Aplasia
Poland Syndrome
Pulmonary Embolus
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
Appearance can result from variety of sources
Technical factors (rotation)
Chest wall abnormalities
Lung parenchymal abnormalities
Airway issues
Vascular abnormalities
Appearance of unilateral hyperlucent lung may be result of compensatory hyperinflation due to contralateral lung abnormality
Decubitus views can be helpful
Chest CT may be necessary in confusing cases
Helpful Clues for Common Diagnoses
Endobronchial Obstruction/Foreign Body
Food is most common aspirated foreign body
Peanuts most common food aspirated
Frequency of right vs. left bronchial tree involvement equal in young children
In adults, right > left
Air-trapping occurs distal to obstruction more commonly than atelectasis in children
Lateral decubitus radiographs helpful
Persistent air-trapping in obstructed lung
Fluoroscopy or expiratory images can also be utilized
Asthma
Most common chronic childhood disease
Airway inflammation results in intermittent airflow obstruction
Chest radiograph typically obtained to rule out other etiologies or complications
May be normal
May show bilateral hyperinflated, hyperlucent lungs
When lungs are asymmetrically involved, unilateral hyperlucent lung appearance may result
Must consider aspirated foreign body in these situations
Pneumothorax
Wide spectrum of etiologies in pediatric population
Can mimic appearance of unilateral hyperlucent lung
Radiolucent space lacking pulmonary markings
White pleural line visible
Helpful Clues for Less Common Diagnoses
Swyer-James Syndrome
Postinfectious obliterative bronchiolitis
Viral
Bacterial
Mycoplasma
Arrest of progressive normal lung growth secondary to vascular compromise
Small hyperlucent lung
Attenuated pulmonary vascularity
Air-trapping during expiration on high-resolution chest CT
Extrinsic Airway Compression by Mass Lesion
Any mass lesion in mediastinum or hila may compress tracheobronchial tree
Lymphadenopathy
Foregut duplication cysts
Neoplasm
Causative mass may not be apparent on plain radiograph
Chest CT may be necessary
3D reformations can be helpful in identifying area of narrowing of tracheobronchial tree
Vascular Ring/Sling
Common forms that cause tracheobronchial compression
Results in air-trapping and hyperlucency
CT or MR angiography diagnostic
Scimitar Syndrome
a.k.a. hypogenetic lung syndrome, pulmonary venolobar syndrome
Involved lung is hypoplastic
Systemic arterial supply
Venous return, typically to IVC
Resembles scimitar (Turkish sword)
Compensatory hyperinflation of contralateral lung
Appears hyperlucent
Bulla
Thin-walled pulmonary parenchymal air-filled space
Commonly seen with emphysema
α-1-antitrypsin in children/adolescents
Idiopathic
Can be seen with connective tissue disorders, such as Marfan syndromeStay updated, free articles. Join our Telegram channel
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