and Janesh Gupta2
(1)
Fetal Medicine, Rainbow Hospitals, Hyderabad, Telangana, India
(2)
University of Birmingham Birmingham Women’s Hospital, Birmingham, UK
SFE1
All of the following are causes of premature ovarian failure except:
A.
Fragile X syndrome
B.
Kallmans syndrome
C.
Mumps oophoritis
D.
Pelvic irradiation
E.
Turner’s syndrome
SFE2
Among the following, select the strongest prognostic factor associated with recurrent miscarriages:
A.
Fibroids
B.
Increasing maternal age
C.
Polycystic ovarian disease
D.
Positive anticardiolipin antibodies
E.
Smoking
SFE3
All of the following may adversely affect male fertility except:
A.
Anabolic steroids
B.
Cannabis addiction
C.
Moderate alcohol consumption
D.
Tobacco consumption
E.
Varicoceles
SFE4
Post testicular causes account for the following percentage of male infertility:
A.
10 %
B.
20 %
C.
30 %
D.
40 %
E.
50 %
SFE5
Choose the first option of management for mild male factor infertility:
A.
In vitro fertilisation
B.
Six cycles of IUI along with clomiphene citrate
C.
Six cycles of IUI alone
D.
Three cycles of IUI with clomiphene citrate
E.
Three cycles of IUI alone
SFE6
Average pregnancy rated with ICSI (intracytoplasmic sperm injection)
A.
10–15 %
B.
15–25 %
C.
30–40 %
D.
50–60 %
E.
60–70 %
SFE7
The growth factor implicated in mediating the effects of ovarian hyperstimulation is:
A.
Insulin-like growth factor
B.
Placental growth factor
C.
Transforming growth factor α
D.
Transforming growth factor β
E.
Vascular endothelial growth factor
SFE8
Which one of the following statements is correct regarding recurrent miscarriage?
A.
Antiphospholipid syndrome, if found to be the cause of recurrent miscarriage, is untreatable.
B.
Antiphospholipid antibodies are present in 15 % of women with recurrent miscarriage.
C.
Cervical weakness (incompetence) is a recognised cause of first-trimester recurrent miscarriage.
D.
One of the partners carries a chromosomal abnormality in at least 25 % of couples with recurrent miscarriage.
E.
Recurrent miscarriage is defined as the loss of two or more consecutive pregnancies before 24 weeks gestation.
SFE9
Which ONE of the following is correct in relation to the prevalence of the main causes of infertility in the UK?
A.
Factors in the male causing infertility (10 %)
B.
Fibroids (30 %)
C.
Ovulatory disorders (10 %)
D.
Tubal damage (50 %)
E.
Unexplained infertility (no identified male or female cause) (25 %)
SFE10
Which ONE of the following clinical scenarios is considered diagnostic of polycystic ovarian syndrome?
A.
Infrequent periods, elevated testosterone
B.
Infrequent periods, infertility, low day 21 serum progesterone
C.
Infrequent periods, impaired glucose tolerance, obesity
D.
Polycystic ovaries, obesity, low day 21 serum progesterone
E.
Polycystic ovaries, elevated LH:FSH ratio, obesity
SFE11
A 34-year-old woman, who has been trying to conceive for 3 years, is referred to the infertility clinic for further management. Which ONE of the following is an appropriate discussion issue during her clinic counselling?
A.
Altering smoking, alcohol or caffeine intake has no impact on spontaneous or IVF pregnancy success.
B.
Despite having regular monthly menstrual cycles, a mid-luteal serum progesterone test is recommended in order to confirm ovulation.
C.
Laparoscopy is the only reliable method to screen for tubal abnormalities.
D.
Low serum progesterone in the mid-luteal phase of their cycle confirms ovulation.
E.
There is a need for an endometrial biopsy to exclude luteal phase defect.
SFE12
A 40-year-old woman, who has been trying to conceive for 3 years, is offered IVF (in vitro fertilisation) as a treatment option by her fertility specialist. Which ONE of the following is an appropriate discussion issue during her clinic counselling?
A.
Ovarian volume, ovarian blood flow and inhibin B usefully predict IVF success rate.
B.
Preimplantation genetic diagnosis (PGD) of the embryo is required prior to its uterine transfer.
C.
Progesterone administration is not required following embryo transfer.
D.
Salpingectomy prior to IVF is beneficial in women with hydrosalpinges.
E.
The chance of a live birth following IVF treatment increases with rising female age.
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