Patient Story
A 14-year-old girl presents with a red face and a history of easy facial flushing over the last two years (Figure 97-1). Her face has become persistently redder and she would like some treatment.
Her mom is in the room and has similar redness in her face. The family is from northern European heritage. The girl also has developed some “pimples.” Physical examination reveals some papules and erythema. No comedones are seen. She knows that the sun makes it worse but finds that many sunscreens are irritating to her skin. The patient is started on 0.75 percent metronidazole gel once daily. She agrees to wear a hat and stay out of the sun during the middle of the day. She will continue to look for a sunscreen she can tolerate. She knows that precipitating factors for her include hot and humid weather, alcohol, hot beverages, and spicy foods.
Introduction
Rosacea is an inflammatory condition of the face and eyes that mostly affects adults but can start in childhood. Most commonly the face becomes reddened over the cheeks and nose and this is often accompanied by telangiectasias and a papulopustular eruption (Figures 97-2 and 97-3).
Synonyms
Epidemiology
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Common in fair-skinned people of Celtic and northern European heritage.
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Women and girls are more often affected than men and boys.
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Men are more prone to the extreme forms of hyperplasia, which causes rhinophymatous rosacea. However, even young women can have rhinophymatous rosacea. (Figure 97-4).
Etiology and Pathophysiology
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Although the exact etiology is unknown, the pathophysiology involves nonspecific inflammation followed by dilation around follicles and hyperreactive capillaries. These dilated capillaries become telangiectasias (Figures 97-5).
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As rosacea progresses, diffuse hypertrophy of the connective tissue and sebaceous glands ensues (Figure 97-4).
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Alcohol may accentuate erythema, but does not cause the disease. Rosacea runs in families.
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Sun exposure may precipitate an acute rosacea flare, but flare-ups can happen without sun exposure.
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A significant increase in the hair follicle mite Demodex folliculorum is sometimes found in rosacea.1 It is theorized that these mites play a role because they incite an inflammatory or allergic reaction by mechanical blockage of follicles.
Risk Factors
Genetics, Demodex infestation,1 sun exposure.

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