We thank Ms Rolfe for her comments. With respect to her suggestion of a need for increasing the number of data collection points, we agree and did mention this limitation within the article. Unfortunately, the length of time required to recruit, obtain informed consent, set-up, and complete data collection was nearly 30 minutes long. Given that the patients all volunteered for the study and were not compensated, coupled with balancing the time/financial burden on the participants, we chose to perform only this exploratory/hypothesis generating evaluation at one time point. Future studies undoubtedly will benefit from a longitudinal design.

With respect to her second suggestion regarding potential confounders, we must note that, before this study, our group has examined the role of such factors (eg, obesity, diabetes mellitus) not only in transcranial Doppler studies of the middle cerebral artery, but also with respect to the autoregulation index, to ensure that we understood their impact in designing our protocol. These examinations are under consideration for publication but did not alter the findings of our study. However, the patients with diabetes mellitus represent a significant part of all patients with preeclampsia. Nevertheless, we agree that future studies should take into account potential confounders.