Surgical treatment of cancer in any organ requires removal of the primary tumor and areas of potential spread. Cancer of the cervix spreads first by direct extension and second by lymph node metastasis. Direct extension is into the cervix, then to the parametria, and then to the pelvic sidewall. The radical hysterectomy and lymph node dissection performed by Meigs fulfilled these requirements. The high rate of bladder dysfunction and ureter injuries led surgeons to modify the radicality of the operation to avoid the autonomic nerves. Piver and Rutledge published five classes of extended hysterectomy in 1974 to address this modification of the Meigs radical hysterectomy. This classification became inadequate after the widespread adoption of nerve-sparing techniques. In 2007, an international conference in Kyoto organized by Shingo Fujii and Paul Morrow produced the Kyoto classification that is in wide use today. The two classification systems are shown in the tables (see Tables 17.1 and 17.2). The Piver class 2 and the Kyoto type B are similar, but the Kyoto classification includes both type B1 and type B2 to indicate when the parauterine fatty nodal tissue is removed from the ureter to the obturator space. The most significant difference is in the Piver class 3 and Kyoto type C. The Piver class 3 removes the entire cardinal ligament including the autonomic nerves, and the Kyoto type C is divided into C1 which removes just the paracervical tissue cranial to the autonomic nerves, and the type C2 removes the entire paracervix including the autonomic nerves. This book will use the Kyoto classification and the nerve-sparing radical hysterectomy (NSRH) will be type C1.
Table 17.1 Piver-Rutledge Classification of Extended Hysterectomy 1974 | ||||||||||||||||||||||||||||||||||||||||||
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The operative management of cervical cancer can be tailored to the amount of the disease in the cervix.
Stage IA1, less than 3-mm invasion, can be treated with a cone, trachelectomy, or simple hysterectomy. Lymph nodes are not removed unless lymph vascular space invasion (LVSI) is present.
Stage IA2, 3- to 5-mm invasion with negative LVSI, can be treated with radical trachelectomy and pelvic lymph node dissection (PLND), or type B radical hysterectomy and PLND (see Fig. 17.1).
Stage IB1 should be treated with type C1 radical hysterectomy and PLND.
Stage IB2 lesions may be treated with chemoradiation without surgery.
A subset of IB2 tumors that are located on the exocervix and are exophytic are candidates for type C1 radical hysterectomy.
IB2 tumors arising in the endocervix that expand the endocervical canal in a barrel shape will have a high incidence of positive nodes, parametrial involvement, and/or positive margins that will require radiation therapy. Therefore, most surgeons will recommend chemoradiation therapy instead of radical hysterectomy to avoid the complications of radical surgery combined with radiation.
Table 17.2 Querleu-Morrow Classification, Kyoto, Japan, 2007
Type
Ureter
Uterine Vessels
Paracervix (Cardinal Ligament)
Uterosacral Ligament
Vesicouterine Ligament
Vagina
Type A
Not exposed
Cut at the uterus
Cut at the uterus
Cut at the uterus
Not divided
At the cervix
Type B1
Unroofed
Cut at the ureteral tunnel
Cut at the ureteral tunnel
Between the cervix and the rectum
Between the cervix and the bladder
1 cm
Type B2
Unroofed
Cut at the ureteral tunnel or laterally
Cut at the ureter tunnel. Remove the lymphatic connective tissue to the origin of the uterine artery.
Between the cervix and rectum
Between the cervix and the bladder
1 cm
Type C1
Mobilized to the bladder
Divided at their origin from the internal iliac vessels
Divided at the internal iliac vessels. The autonomic nerves are preserved dorsal to deep uterine vein
Divided at the rectum
Divided at the bladder
1.5 to 2 cm
Type C2
Mobilized to the bladder
Divided at their origin from the internal iliac vessels
The entire paracervix including that dorsal to the deep uterine vein and includes the autonomic nerves
Divided at the rectum
Divided at the bladder
1.5 to 2 cm
Adapted from Morrow PC. Morrow’s Gynecologic Cancer Surgery. 2nd ed. Encinitas, CA: South Coast Medical Publishing; 2013:583, Table 10-16.
Type C2 radical hysterectomy is indicated when the tumor is found to be invading the paracolpos, and the patient has chosen radical surgery as treatment even if bladder dysfunction may result.
This chapter will discuss the surgical techniques for type B1 and type C2.
Type C1 will be discussed in Chapter 18, Nerve-Sparing Radical Hysterectomy.Stay updated, free articles. Join our Telegram channel
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