Peanut Allergy
Katherine S. L. Tuttle
Tanya M. Laidlaw
The Natural Progression of Peanut Allergy: Resolution and Possibility of Recurrence
Fleischer DM, Conover-Walker MK, Christie L, et al. J Allergy Clin Immunol. 2003;112(1):183–189
Background
Peanut allergy was once thought to be a lifelong condition, but current literature estimates that 20% of children actually outgrow their allergy.1 However, there are several reported cases of children who passed an oral peanut challenge (OPC) and later exhibited allergic symptoms to peanut, suggesting ongoing assessment is crucial. This study sought to describe the natural history of peanut allergy to provide accurate prognostic information.
Objectives
To describe the natural progression of peanut allergy and characterize dietary patterns and allergy recurrence in patients who passed an OPC.
Methods
Retrospective chart review in 2 US centers from 2000 to 2002.
Patients
Chart review included 84 patients ages 4 to 15 years with peanut allergy and peanut-specific Immunoglobulin (Ig) E levels of <5 kU/L. Survey included 64 patients ages 4 to 20 years who passed an OPC. Select exclusion criteria: history of multiple peanut challenges.
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