Chapter 519 Orthostatic (Postural) Proteinuria
Orthostatic proteinuria is the most common cause of persistent proteinuria in school-aged children and adolescents, occurring in up to 60% of children with persistent proteinuria. Children with this condition are usually asymptomatic, and the condition is discovered on routine urinalysis. Patients with orthostatic proteinuria excrete normal or minimally increased amounts of protein in the supine position. In the upright position, urinary protein excretion may be increased 10-fold, up to 1,000 mg/24 hr (1 g/24 hr). Hematuria, hypertension, hypoalbuminemia, edema, and renal dysfunction are absent.
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