Medication Versus Behavioral Treatment in Attention Deficit Hyperactivity Disorder
Rachel S. Sagor
Elizabeth Pinsky
A 14-Month Randomized Clinical Trial of Treatment Strategies for Attention-Deficit/Hyperactivity Disorder. The MTA Cooperative Group. Multimodal Treatment Study of Children With ADHD
Arch Gen Psychiatry. 1999;56(12):1073–1086
Background
Attention deficit hyperactivity disorder (ADHD), the most common psychiatric illness among children, has significant effects on social, familial, and academic functioning. Management typically includes medications, behavioral treatment, or a combination of these. Despite short-term data regarding efficacy of these 2 modalities, prior to this study there were no long-term (>4 months) studies comparing these time-intensive interventions.
Objectives
To compare long-term outcomes of different treatment modalities in the management of ADHD.
Methods
Randomized controlled trial at 6 US sites from 1994 to 1998.
Patients
579 children ages 7 to 9 years who met Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) criteria for ADHD, combined type. Select exclusion criteria: inability to participate in interventions, treatment requirements beyond study ability.
Intervention
Participants were randomized to one of four 14-month long treatments: intensive medication management (monthly 30-minute medication visits); intensive behavioral treatment (parent training, child-focused treatment, and school-based interventions); combination intensive management (all components of intensive medication management and behavioral treatment); or standard community care (formal initial evaluation and subsequent care at provider’s discretion). Side effects were monitored monthly using parent rating scales.