Celiac disease (CD) is an autoimmune enteritis caused by gluten ingestion. It affects up to 3.5% of those with GI symptoms or a positive family history.¹ Genetic susceptibility plays a strong role as nearly all patients with CD carry a high-risk HLA allele (HLA-DQ2 or HLA-DQ8). Prior studies suggested a window of tolerance between 4 to 6 months of age, during which infants may achieve immune tolerance through early gluten introduction due to potential protective effects of breastfeeding.^2,3 Some groups suggested gluten introduction during this period while others avoided making specific recommendations. This trial investigated the impact of timing of gluten introduction on CD development.