Through treatment improvements, the number of adult survivors of childhood cancer continues to grow, with an estimated 420,000 survivors in the United States currently.¹ However, these increased cure rates are not without morbidity. Previous studies identified some adverse health outcomes in cancer survivors, but had small sample sizes. This study used the Childhood Cancer Survivor Study (CCSS) to survey thousands of survivors for over 3 decades and collect data on several health conditions.

To establish frequency and severity of chronic medical conditions in patients ≥5 years after treatment for childhood cancer and identify those at the highest risk for developing serious and incapacitating health conditions.

Retrospective cohort study using CCSS data of patients diagnosed at 26 US centers between 1970 and 1986.