Herbals and Natural Products










































































































































































Herb Common Name/Rating * Synonyms Active Ingredient Uses Present in Milk Safety/Efficacy
Aloe vera
AAP –
H L3
W –

Asparagus
Aloe barbadensis , A. capensis, vera


Wild asparagus root
Polysaccharide, glucomannan



Asparagus racemosus
Wound healing and small burns Unknown, probably none when applied to skin Orally is a strong purgative; oral dosing not recommended during lactation. Dermal use ok.
Nourishing herb; used in those debilitated or conv galactagogue (1 g powdered root per day in milk or juice).
Blessed thistle
AAP –
H L3
W –
Borage
AAP –
H L5
W –
Botulism
AAP –
H L3
W –
Borage officinalis
Toxin
Many chemicals and volatile oils



Pyrrolizidine alkaloid
Gastrointestinal symptoms



Pain therapy
Unknown This is not a galactagogue. It is a different plant from milk thistle. No known toxicity.
Many uses.
Contraindicated in pregnancy and lactation.
In natural cases of botulism toxin does not get into the milk. Pharmaceutical product Botox treatment unlikely to reach milk.
Cannabis
AAP 2
H L5
W –
Capsaicin
AAP –
H L3
W –
Marijuana
Capsicum
Δ9-Tetrahydrocannabinol (THC)


Topical anesthesia
Sedative, hallucinogen Yes



Unknown
Remains in infant’s system for weeks, especially in fat.
Available as a cream, lotion, or oral tablets. Used where vasodilation or warmth is needed. Can cause burning, stinging. Do not use on breasts.
Chamomile
AAP –
H L3
W –
Matricaria recutita, Aster Aceae family Terpenoids (coumarins), flower heads Antiinflammatory, carminative, antiseptic, sedative (all unproved) Unknown Potential for allergic reaction. Animal studies question safety in pregnancy and lactation.
Cohosh (black)
AAP –
H L4
W –
Cimicifuga racemosa, black cohosh, black snakeroot, found in Lydia Pinkham’s compound Estrogenic compounds, tannins, terpenoids, use roots and rhizome Dysmenorrheal, dyspepsia, rheumatism, menopause Unknown May cause hypotension; could decrease milk production? Efficacy and safety in lactation.
Cohosh (blue)
AAP –
H L5
W –
Caulophyllum, blue cohosh, squaw root Roots and rhizome, methylcytosine, caulosaponin Uterine stimulant, emmenagogue, increased blood pressure, like nicotine, induces labor Safety of concern, can constrict coronary vessels; leaves and seeds are known to be toxic.
Can induce labor.
Comfrey
FDA banned
AAP –
H L5
W –
Symphytum officinale Roots and rhizome and leaves, allantoin, hepatotoxic, pyrrolizidine alkaloids “Wonder drug,” heals wounds, used as poultice, used as tea Yes Venoocclusive disease causing hepatic failure. Banned in many countries; unsafe.
Echinacea
AAP –
H L3
W –
Echinacea angustifolia, coneflower Whole plant, flowers, dried roots Immunostimulant, antiinfective, tested for upper respiratory infections Unknown Has been studied; effective in short courses, not continual use. No known toxicity; probably safe during lactation.
Evening primrose
AAP –
H L3
W –
Oenothera biennis Biennis, oil from seeds, cis-gamma-linoleic acid (GLA), a precursor of prostaglandin E 1 , essential fatty acids (EFA) Lower cholesterol, lower blood pressure, lower dysmenorrhea, mastalgia, eczema Yes Efficacy: conflicting reports. Safety: +/− probably in small amounts. Supplements increase EFA in milk ; increase bleeding time. Do not use with phenol thiazines.
Fennel
AAP –
H L4
W –
Foeniculum vulgare Dried ripe fruit, volatile oil, transanethole estrogenic effect Carminative, loosen phlegm, galactagogue, increase libido Probable Volatile oil can be toxic; use only fruits (seeds). Because of estrogenic effect, its reputation as a galactagogue is questioned.
Fenugreek
AAP –
H L3
W –



Feverfew
Not rated
Trigonella foenumgraecum, Greek hayseed


Chrysanthemum partenium
Bachelor’s button
Dried ripe seeds, diosgenin, and alkaloids smell like maple syrup



Leaves extract tincture
Hypoglycemia, galactagogue, anticoagulant, see text



Associated with migraines. Menstrual irregularity antiinflammatory
Probable
Unknown
Risk: cross allergy to chrysanthemum family. Probably in milk; infants smell of maple syrup. No studies of efficacy.
Enhances effect of warfarin contraindicated during pregnancy. Value as galactagogue undocumented; decreases platelet aggregation.
Garlic (Supplement form)
AAP –
H L3
W –
Lily family: Allium sativum, poor man’s treacle, clove garlic, common garlic, allium, stinking rose Alliin, ajoens Has 125 different uses, some contradictory, both high and low blood pressure, antibacterial, antithrombotic, lower cholesterol Yes Can cause colic in breastfed infants. Can enhance warfarin. Not tolerated by some infants.
Galactagogues: increase milk supply
Fenugreek (Greek hayseed)
Goats rue (Galega officinalis)
Alfalfa (member pea family) seeds can be toxic
Borage contains amabilene/relieves pain can cause venoocclusive disease
Antigalactagogues: decrease milk supply. Fennel and estrogenic effects; oil is toxic. Peppermint, sage, parsley (tabbouleh salad) agnus castus (monk’s pepper)
Jasmine flowers applied to breast
Ginkgo
AAP –
H L3
W –
Ginkgo biloba Flavones and glycosides, seeds, ginkgotoxin, ginkgo biloba extract (GBE), leaves for tea Herbal antioxidant Unknown Placebo-controlled studies suggest no efficacy in young adults. Use in elderly more effective. Conflicting reports of safety. Not recommended in lactation.
Enhances the effect of warfarin. Can cause bleeding even alone.
Ginseng
AAP –
H L3
W –
Panax ginseng ( P. quinquefolius ), Asian ginseng Root and extracts Panacea, cure-all, adaptogen, strengthening, increasing mental capacity Unknown Too much has been written, with considerable conflict of opinion. Ginseng abuse syndrome; research done mostly by manufacturers. Safety: not long-term use; efficacy questionable. Not recommended in lactation. Reduces effect of warfarin.
Grapefruit seed extract
AAP –
H –
W –
Grape seed
AAP –
H –
W –
Flavonols
Capsules, tablets (50-100 mg daily supplementation/150-300 mg daily therapeutic
Antimicrobial inhibits intestinal cytochrome 450 Noted to have autoinfection, antiviral, antibacterial, and antifungal effects. Grapefruit is known to contain quinine, especially in the bitter skin and section fibers. Recommended as an extract for use by direct application on sore nipples. If it has antiinfectious properties, it should be effective when traumatized nipples have become infected.
Antioxidant, anticancer agent for varicose veins, circulatory problems. May increase risk for bleeding.
Herbal teas Tablets, powders, tea leaves May include Gerry mander, comfrey, mistletoe, skull cap, pennyroyal, all of which are toxic. Always check constituents. Many cause hepatotoxicity and/or venous occlusive disease. Many associated with hemorrhagic disease.
Kava
AAP –
H L5
W –


Licorice root
Piper methysticum, Kew, tonga



Glycyrrhiza glabra family
Roots/rhizomes, dihydropyrones with central nervous system activity, kavapyrones
Glycyrrhizin acid rhizomes and roots
Inebriation, muscle relaxants, alternative to penzodiapams


Laxative and cure for gastritis
Unknown
Laxative, gastritis, hypokalemia
Unsafe in pregnancy and lactation. Numbs the mouth; nauseating. Causes yellow discoloration of the skin, hair, nails.
Known for 4000 years; large doses: weakness, edema, weight loss, hypertension, hypokalemia, and confusion. Consumption should be avoided in pregnancy and lactation.
Milk thistle (holy thistle) (not blessed thistle)
AAP –
H L3
W –
Raspberry root
AAP –
H –
W –
Silybum marianum, St. Mary’s thistle
Rubis idaeus leaves
Fruits, flavolignans, inhibits oxidative damage to cells
Promote diverse urinary tract infections, morning sickness, ease labor
Protective effect, concentrates in the liver Unknown Galactagogue. Problem: can cause allergy; low oral bioavailability. Probably safe. Poor oral bioavailability.
Safe in pregnancy and lactation.
Sage
AAP –
H L4
W –
Salvia officinalis Fresh leaves and fresh flowering aerial parts, dried leaves, and oils prepared as extracts and teas Loss of appetite, inflammation of mouth and pharynx, excessive perspiration Unknown Contraindicated in pregnancy. Suppresses lactation. Okay as a flavoring.
St. John’s wort
AAP –
H L2
W –







Silymarin (micronized)
AAP –
H L3
W –
Hypericum perforatum
Hyperforin
Flavonolignans seeds
Silybum marianum,
Milk thistle,
BIO-C
Naphthodianthrones, phloroglucinols
Antioxidant








Liver protectant possibly
Depression Not detected
Galactagogue
Can cause photosensitivity. Risk for self-medication for a serious psychiatric problem. Can reduce the effect of warfarin, induce cytochrome P-450 enzyme system. Dose variable in different products.
Poorly soluble in water micronized for oral use as galactagogue.
Valerian root
AAP –
H L3
W –
Valeriana officinalis, all-heal, Amantilla, setwell, setewale, capon’s tail, heliotrope, vandal root Liquid, tablets, tea, volatile oil Nervousness and insomnia Unknown Not recommended in lactation. Used as a sedative, hypnotic.

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Jul 13, 2019 | Posted by in PEDIATRICS | Comments Off on Herbals and Natural Products

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