Objective
We aimed to utilize genome-wide expression analysis to identify molecular pathways that may contribute to endometrial cancer resistance to doxorubicin (DOX) and that also represent therapeutic targets to increase DOX sensitivity.
Study Design
Ten endometrial cancer cell lines were subjected to gene expression analysis. Sensitivity of each endometrial cell line to DOX was quantified by dimethylthiazoldiphenyltetrazoliumbromide cell proliferation assay. Pearson’s correlation test was used to identify genes associated with response to DOX. Genes associated with DOX responsiveness were analyzed, and identified pathways were subjected to targeted inhibition.
Results
Pearson’s correlation analysis identified 2871 genes associated with DOX resistance ( P < .05), which included members of the Src pathway. Targeted inhibition of the Src pathway increased DOX sensitivity in RL 95-2 ( P < .0001), HEC 1B ( P < .001), MEF 296 ( P < .05), and MEF 280 ( P = .14) cell lines.
Conclusion
Genomic analysis can identify therapeutic targets such as the Src pathway that may influence endometrial cancer DOX sensitivity.
The American Cancer Society estimates 42,160 new cases of endometrial cancer will be diagnosed in 2009 and about 7780 women will die from the disease. It represents the most common gynecologic malignancy. Most patients with endometrial cancer present with symptomatic, early-stage disease, such that primary surgical therapy is most frequently curative. Patients with nonlocalized, advanced, or recurrent disease are managed with systemic therapy but generally experience much less favorable survival. Although reported response rates to systemic hormonal and cytotoxic therapy for advanced and recurrent endometrial cancer vary dramatically, overall median survival is generally extremely poor.
Advanced or recurrent endometrial cancer is commonly treated with different combinations of cytotoxic chemotherapy including doxorubicin (DOX), cisplatin, and paclitaxel with or without hormonal agents. A recent metaanalysis of randomized controlled trials comparing chemotherapy regimens for patients with advanced or recurrent endometrial cancer demonstrated superiority of combination over single-agent chemotherapy, and furthermore, that paclitaxel in combination with cisplatin and DOX increased response rates and median survival but also increased toxicity.
Despite such data, in general, efficacy of systemic therapy for recurrent or advanced-stage endometrial cancer is suboptimal. Moreover, currently no reliable clinical tools exist to enable specific therapies to be directed at the individual patients most likely to benefit. As a result of subsequent empiric treatment decision making, many patients receive inactive, yet potentially toxic therapies, without substantial benefit. Such a dilemma, although unfortunately common in many aspects of clinical oncology today, underscores the importance of efforts to develop personalized-medicine approaches to gynecologic cancer.
We and others previously reported the development of genomic signatures associated with chemotherapy response to ovarian and other human cancers as well as the status of oncogenic signaling pathways. In the current study, we sought to utilize global gene expression analysis to identify pathways that not only contribute to endometrial cancer cell resistance to DOX but that may also represent therapeutic targets to increase sensitivity to the drug.
Materials and Methods
Cell lines
Endometrial cancer cell lines KLE, HEC 1B, HEC 1A, RL 95-2, and AN3-Ca were obtained from the American Type Culture Collection (Manassas, VA); Ishikawa cell lines from Sigma Aldrich (St Louis, MO); and EN, MEF 319, MEF 280, and MEF 296 from Deutsche Sammlung von Mikroorganismen und Zellkulturen, DSMZ (Braunschweig, Germany). Cell lines were maintained in RPMI 1640 supplemented with 10% fetal bovine serum, 1% sodium pyruvate, and 1% nonessential amino acids. All tissue culture reagents were obtained from Sigma Aldrich.
Cell proliferation assays
Methods describing drug sensitivity assays have been previously described. In brief, cells were seeded in 96 well plates 12 hours before treatment at a density of 5000 cells/well. After 96 hours of incubation with DOX at increasing doses (range, 10–1000 μg/mL), dimethylthiazoldiphenyltetra-zoliumbromide (MTT) was added to each well at a final concentration of 0.5 mg/ml and incubated further for 4 hours at 37°C.
To stop the reaction, the medium was removed and 100 μL dimethylsulfoxide was added. The absorbance at 570/650 nm was detected using a microplate enzyme-linked immunosorbent assay reader (SpectraMax 190; Molecular Devices, Sunnyvale, CA). In vitro cytotoxicity was determined by percent cell survival, which was expressed as percent control. The concentration at which proliferation was decreased by 50% was used to define the median inhibitory concentration (IC50).
All experiments were repeated in triplicate and mean IC50 values calculated. DOX sensitivity/resistance was thus quantified and genomic data analyzed to identify biologic pathways associated with DOX sensitivity/resistance. The effect of a targeted pathway inhibitor (SU6656) on cell proliferation as a single agent and in combination with DOX was evaluated using MTT assay as described before (SU6656 dose range, 10–1000 μg/mL). Sum-of-square F test was used to determine the statistical significance of differences in IC50 values for DOX ± SU6656.
RNA extraction for gene expression assessment
Ribonucleic acid (RNA) was extracted from all 10 endometrial cell lines using QIAGEN RNeasy minikit (QIAGEN, Valencia, CA). Approximately 1 × 10 7 cells from each endometrial cell line were disrupted, and deoxyribonucleic acid was sheared by passing the lysate through a 21-gauge needle 10 times.
Total RNA was extracted following the QIAGEN RNeasy minikit protocol. Quality of the RNA was measured using an Agilent 2100 bioanalyzer (Agilent, Santa Clara, CA). Approximately 54,000 well-substantiated human messenger RNA (mRNA) genes were analyzed using the Affymetrix 133 plus 2.0 GeneChip (Affymetrix, Santa Clara, CA). Messenger RNA and the target probes were prepared, hybridized, washed, and scanned according to the manufacturer’s instructions. The signal intensity measurements computed in the Affymetrix Microarray Analysis Suite (version 5.0; Affymetrix) served as a relative indicator of the level of expression.
Statistical analysis of gene expression
Gene expression data from the 10 endometrial cancer cell lines was generated using Affymetrix U133_2 Plus Genechips. Expression data were subject to background correction and normalization using the MAS5 algorithm implemented in Affymetrix Expression Console. A Pearson’s correlation test was utilized to evaluate gene expression data and cell line DOX IC50 data. The probe IDs with a P < .05 were considered to demonstrate significant differential expression and used further for pathway analysis.
Pathway analysis
In an effort to provide a relevant biologic context to the genes identified to be associated with in vitro DOX responsiveness, an analysis of biologic pathway relationships was performed using the commercially available software, Ingenuity Pathway Analysis (IPA; Ingenuity Systems, Redwood City, CA). This web-based, literature-curated application correlates gene expression array data to relevant biological pathways, such that one can identify the networks, molecular mechanisms, and biological processes most relevant to developed data.
IPA software uses genes provided for analysis by the user as seeds, from which it generates networks, which are scored based on the number of network-eligible study genes they contain, compared with the total number of genes in that network. The higher the score, the lower the probability that the observed number of network-eligible genes would be observed by random chance. Ingenuity pathway analysis was thus performed on the genes identified in our analysis to be associated with DOX sensitivity/resistance in an effort to identify potential activated molecular oncogenic pathway targets.
Results
DOX sensitivity/resistance was quantified by IC50 for all 10 endometrial cancer cell lines, enabling cells to be ranked from most sensitive to most resistant as follows: HEC 1B, EN, MEF 319, MEF 280, AN3-Ca, KLE, HEC 1A, Ishikawa, MEF 296, and RL95-2. Pearson’s correlation identified 2871 genes ( P < .05) associated with in vitro DOX sensitivity/resistance ( Supplementary Table ). The Src gene was represented among the genes associated with DOX sensitivity with a P value of .038 and a Pearson R score of 0.66.
In an effort to place gene expression findings into a relevant biologic contest, we used IPA (Ingenuity Systems). IPA analysis identified a series of biologic pathways (termed canonical pathways) within the 2871 genes. These canonical pathways represent previously reported signaling and/or metabolic systems and include gene networks that have previously been reported to interact biologically.
We identified 20 canonical pathways with P < .01 associated with DOX resistance. These canonical pathways ( Table ) include B cell receptor signaling ( P < .001), vitamin D receptor/retinoid X receptor activation ( P < .001), death receptor signaling ( P < .001), interleukin (IL)-6 signaling ( P < .01), IL-6 signaling ( P < .01), acute-phase response signaling ( P < .01), CD40 signaling ( P < .01), and G protein-coupled receptor signaling ( P < .01).
| Biologic/canonical pathway | P value |
|---|---|
| Role of PKR in interferon induction and antiviral response | .0001 |
| Antigen presentation pathway | .0001 |
| B cell receptor signaling | .0002 |
| IL-15 production | .0003 |
| VDR/RXR activation | .0005 |
| Role of pattern recognition receptors in recognition of bacteria and viruses | .0006 |
| Death receptor signaling | .0008 |
| IL-6 signaling | .0012 |
| PPAR signaling | .0018 |
| Interferon signaling | .0018 |
| 4-1BB signaling in T lymphocytes | .0019 |
| Acute phase response signaling | .0027 |
| Agrin interactions at neuromuscular junction | .0033 |
| IL-12 signaling and production in macrophages | .0033 |
| IL-10 signaling | .0033 |
| CD40 signaling | .0039 |
| Aryl hydrocarbon receptor signaling | .0039 |
| Role of RIG1-like receptors in antiviral innate immunity | .0050 |
| G protein-coupled receptor signaling | .0060 |
| Dendritic cell maturation | .0062 |
Of interest, the Src tyrosine-protein kinase gene network was overrepresented in 5 of 20 of these biologic/canonical pathways (25%), namely G protein-coupled receptor signaling ( P = .006), Wnt/β-catenin signaling ( P = .01), aryl hydrocarbon receptor signaling ( P = .004), thrombin signaling ( P = .03), and Fcγ receptor-mediated phagocytosis in macrophages and monocytes ( P = .04). Figure 1 illustrates 1 such Src gene network.
In light of the presence of Src gene networks in the genes associated with DOX resistance as well as the previously reported role of Src in proliferation, apoptosis, and oncogenesis, we elected to interrogate the pathway using an Src inhibitor (SU6656) as a potential therapeutic tool to increase endometrial cell sensitivity to DOX. We sought to evaluate the effect of targeted Src-pathway inhibition on DOX sensitivity/resistance in 4 endometrial cancer cell lines (MEF 280, MEF 296, RL95-2, and HEC 1B) that demonstrated a range of baseline sensitivities to DOX. To accomplish this, we used SU6656, a potent small-molecule Src family kinase inhibitor.
The effect of DOX in the presence and absence of SU6656 was evaluated using MTT proliferation assays. Inhibition of the Src pathway using SU6656 produced a statistically significant increase in DOX sensitivity (measured by IC50 value) in 3 of 4 cell lines, RL95-2 ( P < .0001), HEC 1B ( P < .001), and MEF 296 ( P < .001) ( Figures 2 , A-C). A left shift in the dose-response curve ( Figure 2 , D) was also noted in the DOX-sensitive cell line MEF 280, but this increase in sensitivity did not reach statistical significance ( P = .14).
Comment
Advanced-stage or recurrent endometrial cancer has a poor prognosis, and conventional empiric treatment strategies with single-agent and combination cytotoxic therapies have produced little improvement in survival despite the potential for significant toxicity. Throughout treatment for recurrent endometrial cancer, prolongation of survival and the successful maintenance of quality of life remain important goals. Improving our ability to manage the disease by optimizing the use of existing drugs and/or developing new agents is essential in this endeavor. To this end, individualizing treatments by identifying patients who will, and will not, respond to specific agents will potentially increase the response rates and limit the incidence and severity of toxicities that compromise not only the quality of life but also the ability to tolerate further therapies.
In the current study, we sought to identify genes and gene pathways related to DOX chemoresponse. Furthermore, we aimed to manipulate these pathways to increase endometrial cancer DOX sensitivity. We identified the Src-tyrosine kinase pathway to be associated with resistance to DOX, a commonly used cytotoxic chemotherapeutic drug used in the treatment of advanced endometrial cancer.
The Src kinases, including c-Src, are a family of nonreceptor tyrosine kinases involved in regulating pathways involved in cell proliferation, motility, adhesion, and survival in both normal and transformed cells. The Src kinase pathway has been demonstrated to be activated in many human cancers, such as lymphoma, gastric, breast, colon, ovarian, bladder, lung, and pancreatic cancer, and has been associated with cancer cell proliferation, motility, invasion, angiogenesis, and resistance to apoptosis.
In pancreatic cancer cells, insulin-like growth factor-1 is known to be overexpressed, activating the Src pathway leading to cell invasion, proliferation, and vascular permeability. The Src family kinases have also been linked to epidermal growth factor receptor, fibroblast growth factor receptor, hepatocyte growth factor/scatter factor receptor, colony-stimulating factor 1 receptor, stem cell factor receptor, and vascular permeability factor/vascular endothelial growth factors, all of which have been implicated in tumorigenesis. In colorectal adenocarcinoma, Src activation frequently has been reportedly high and has been associated with highly metastatic phenotypes and as an independent predictor of prognosis.
Activation of the Src pathway has been associated with resistance of several human cancer types to chemotherapy. Moreover, the pathway has also been shown to be a viable therapeutic target as evidenced by the increased chemosensitivity associated with pharmacologic Src-pathway inhibition. Specifically, activation of the Src pathway has been demonstrated to be associated with pancreatic adenocarcinoma cell resistance to gemcitabine, cholangiocarcinoma resistance to cisplatin, and ovarian cancer resistance to paclitaxel and cisplatin. In the current study, we inhibited the Src pathway with SU6656, which acts as an adenosine triphosphate (ATP) competitive inhibitor, blocking ATP binding and phosphotransferase activity, with significant selectivity for Src relative to other inhibitors in its class.
Although molecular markers of chemoresponse have been reported for many human cancers, the biologic determinants of endometrial cancer response to cytotoxic therapy remain relatively unclear. In the current study, we utilized microarray expression technology to identify genes and gene pathways associated with endometrial cancer cell line sensitivity and resistance to 1 of the most commonly used cytotoxic agents, DOX. In doing so, we have identified a specific biological pathway, Src tyrosine kinase, that appears to be activated in DOX resistant endometrial cancer. With manipulation of this pathway using a selective Src inhibitor, we have demonstrated the ability to increase DOX sensitivity in both resistant and more sensitive endometrial cell lines.
Our findings not only provide insights into the molecular basis to endometrial cancer sensitivity to cytotoxic therapy but also support our previous findings that implicate the Src pathway as an important determinant of human cancer chemosensitivity and also as a viable therapeutic target.
Appendix
| Gene symbol | Probe set ID | Pearson R score | P value |
|---|---|---|---|
| RHBDL2 | 1554895_a_at | 0.999 | 1.90E-11 |
| GJB5 | 206156_at | 0.998 | 9.15E-11 |
| H19 | 224646_x_at | 0.998 | 1.15E-10 |
| KRT15 | 204734_at | 0.998 | 1.33E-10 |
| CRABP2 | 202575_at | 0.998 | 1.40E-10 |
| C12orf59 | 236646_at | 0.998 | 1.43E-10 |
| CYP24A1 | 206504_at | 0.997 | 1.91E-10 |
| CXCL2 | 209774_x_at | 0.997 | 2.25E-10 |
| XYLT1 | 213725_x_at | 0.997 | 2.39E-10 |
| OLR1 | 210004_at | 0.997 | 2.46E-10 |
| HSD17B2 | 204818_at | 0.997 | 2.61E-10 |
| VGLL1 | 215729_s_at | 0.997 | 2.65E-10 |
| C10orf116 | 203571_s_at | 0.997 | 2.68E-10 |
| S100A8 | 202917_s_at | 0.997 | 2.74E-10 |
| OLFM4 | 212768_s_at | 0.997 | 2.74E-10 |
| VGLL1 | 205487_s_at | 0.997 | 2.81E-10 |
| H19 | 224997_x_at | 0.997 | 2.92E-10 |
| S100A9 | 203535_at | 0.997 | 3.15E-10 |
| TIMM13 | 231749_at | 0.997 | 3.16E-10 |
| ASCL2 | 229215_at | 0.997 | 3.35E-10 |
| CLEC7A | 1555214_a_at | 0.997 | 3.56E-10 |
| — | 224348_s_at | 0.997 | 3.80E-10 |
| GATA3 | 209604_s_at | 0.997 | 4.44E-10 |
| KRT13 | 207935_s_at | 0.997 | 4.91E-10 |
| PLAC8 | 219014_at | 0.997 | 5.23E-10 |
| GPR128 | 1553296_at | 0.997 | 5.25E-10 |
| KYNU | 210663_s_at | 0.997 | 6.13E-10 |
| CLEC7A | 221698_s_at | 0.997 | 6.14E-10 |
| CALB2 | 205428_s_at | 0.996 | 7.05E-10 |
| KYNU | 217388_s_at | 0.996 | 7.09E-10 |
| GPR87 | 219936_s_at | 0.996 | 7.14E-10 |
| EDG8 | 221417_x_at | 0.996 | 9.20E-10 |
| WNT4 | 208606_s_at | 0.996 | 9.95E-10 |
| DEFB1 | 210397_at | 0.996 | 1.03E-09 |
| ECAT8 | 215356_at | 0.996 | 1.04E-09 |
| ELF3 | 229842_at | 0.996 | 1.08E-09 |
| LAMB4 | 215516_at | 0.996 | 1.11E-09 |
| GATA3 | 209602_s_at | 0.996 | 1.17E-09 |
| VTCN1 | 219768_at | 0.996 | 1.29E-09 |
| XG | 1554062_at | 0.996 | 1.49E-09 |
| LCN2 | 212531_at | 0.996 | 1.52E-09 |
| COL17A1 | 204636_at | 0.996 | 1.59E-09 |
| EDG8 | 233743_x_at | 0.996 | 1.61E-09 |
| CLEC7A | 1555756_a_at | 0.995 | 1.80E-09 |
| LY6K | 223688_s_at | 0.995 | 1.87E-09 |
| FABP4 | 203980_at | 0.995 | 2.42E-09 |
| PSG1 | 208257_x_at | 0.995 | 2.46E-09 |
| RCSD1 | 225763_at | 0.995 | 2.49E-09 |
| CCND2 | 200951_s_at | 0.995 | 2.51E-09 |
| ELF3 | 210827_s_at | 0.995 | 2.53E-09 |
| TP73L | 209863_s_at | 0.995 | 2.59E-09 |
| HLA-DRA | 210982_s_at | 0.995 | 3.36E-09 |
| — | 229147_at | 0.995 | 3.48E-09 |
| LY6K | 223687_s_at | 0.995 | 3.57E-09 |
| NRXN2 | 209983_s_at | 0.994 | 4.38E-09 |
| CLCA2 | 217528_at | 0.994 | 4.97E-09 |
| LFNG | 228762_at | 0.994 | 5.31E-09 |
| — | 225328_at | 0.994 | 5.53E-09 |
| TP73L | 211194_s_at | 0.994 | 6.14E-09 |
| RNASE7 | 234700_s_at | 0.994 | 6.48E-09 |
| ELF3 | 201510_at | 0.993 | 8.82E-09 |
| FAM83A | 238741_at | 0.993 | 8.99E-09 |
| FAM83A | 239586_at | 0.993 | 1.29E-08 |
| PROM2 | 1552797_s_at | 0.992 | 1.65E-08 |
| — | 239089_at | 0.992 | 2.20E-08 |
| ATP8B1 | 226302_at | 0.992 | 2.23E-08 |
| IFIH1 | 219209_at | 0.991 | 2.52E-08 |
| APCDD1 | 225016_at | 0.991 | 2.93E-08 |
| LOC642587 | 1555942_a_at | 0.990 | 3.74E-08 |
| TFAP2C | 205287_s_at | 0.990 | 3.87E-08 |
| EDG8 | 230464_at | 0.990 | 4.39E-08 |
| ZNF750 | 219995_s_at | 0.990 | 4.57E-08 |
| SPRR3 | 218990_s_at | 0.990 | 4.86E-08 |
| HLA-DRB1 | 209312_x_at | 0.989 | 5.64E-08 |
| PSG4 | 208191_x_at | 0.989 | 5.68E-08 |
| FXYD3 | 202489_s_at | 0.989 | 6.66E-08 |
| PADI3 | 220779_at | 0.989 | 7.06E-08 |
| IRF6 | 1552477_a_at | 0.988 | 8.10E-08 |
| TMEM40 | 222892_s_at | 0.988 | 8.42E-08 |
| — | 1565701_at | 0.988 | 8.62E-08 |
| LOC440028 | 1562606_a_at | 0.988 | 9.60E-08 |
| CCND2 | 200953_s_at | 0.987 | 1.06E-07 |
| — | 1569663_at | 0.987 | 1.11E-07 |
| HLA-DRB1 | 208306_x_at | 0.987 | 1.14E-07 |
| — | 1558821_s_at | 0.987 | 1.26E-07 |
| GATA3 | 209603_at | 0.987 | 1.37E-07 |
| EYA2 | 209692_at | 0.986 | 1.43E-07 |
| RASSF6 | 235638_at | 0.986 | 1.47E-07 |
| GIMAP2 | 232024_at | 0.986 | 1.58E-07 |
| LAMB4 | 234334_s_at | 0.986 | 1.62E-07 |
| HOMER3 | 222222_s_at | 0.986 | 1.63E-07 |
| CLCA2 | 206164_at | 0.986 | 1.87E-07 |
| — | 233685_at | 0.985 | 1.90E-07 |
| RERG | 244745_at | 0.985 | 1.91E-07 |
| ADRB2 | 206170_at | 0.985 | 1.93E-07 |
| CSTA | 204971_at | 0.985 | 2.04E-07 |
| APOL3 | 221087_s_at | 0.985 | 2.13E-07 |
| — | 235350_at | 0.985 | 2.18E-07 |
| CTSB | 200838_at | 0.985 | 2.20E-07 |
| LOC440331 | 231164_at | 0.984 | 2.74E-07 |
| MAPK13 | 210058_at | 0.984 | 3.15E-07 |
| PDE5A | 206757_at | 0.984 | 3.16E-07 |
| — | 233482_at | 0.983 | 3.67E-07 |
| NTF5 | 231785_at | 0.983 | 3.94E-07 |
| TNNI2 | 206393_at | 0.982 | 4.07E-07 |
| PLXNA2 | 213030_s_at | 0.982 | 4.33E-07 |
| LOC642587 | 226755_at | 0.982 | 4.79E-07 |
| HLA-DRB1 /// HLA-DRB3 /// LOC730415 | 215193_x_at | 0.981 | 5.02E-07 |
| C4orf19 | 219450_at | 0.981 | 5.22E-07 |
| PLAC2 | 244374_at | 0.981 | 5.64E-07 |
| TFAP2C | 205286_at | 0.981 | 5.97E-07 |
| CTSB | 200839_s_at | 0.981 | 5.97E-07 |
| C21orf25 | 212875_s_at | 0.981 | 6.03E-07 |
| — | 231035_s_at | 0.981 | 6.06E-07 |
| TMPRSS13 | 223659_at | 0.980 | 7.34E-07 |
| FUT6 | 211882_x_at | 0.979 | 7.56E-07 |
| MLPH | 218211_s_at | 0.979 | 7.95E-07 |
| CTSB | 213274_s_at | 0.979 | 7.99E-07 |
| — | 229385_s_at | 0.979 | 8.12E-07 |
| — | 240034_at | 0.979 | 8.32E-07 |
| ARHGEF7 | 235412_at | 0.979 | 8.65E-07 |
| — | 1557796_at | 0.979 | 8.78E-07 |
| GPR110 | 238689_at | 0.979 | 8.95E-07 |
| B3GALT6 | 226427_s_at | 0.978 | 9.19E-07 |
| — | 243605_at | 0.978 | 9.38E-07 |
| SYCE2 | 237304_at | 0.978 | 9.38E-07 |
| CDH5 | 204677_at | 0.978 | 9.80E-07 |
| TAOK3 | 220761_s_at | 0.978 | 1.01E-06 |
| — | 237276_at | 0.978 | 1.07E-06 |
| HLA-DRB1 /// LOC730415 | 204670_x_at | 0.977 | 1.25E-06 |
| HBQ1 | 220807_at | 0.977 | 1.29E-06 |
| IRF6 | 202597_at | 0.977 | 1.29E-06 |
| SYT7 | 226167_at | 0.976 | 1.39E-06 |
| KLF4 | 221841_s_at | 0.976 | 1.50E-06 |
| MGAM | 206522_at | 0.975 | 1.53E-06 |
| TMEM40 | 219503_s_at | 0.975 | 1.54E-06 |
| LOC647836 /// LOC649279 /// WNT7B | 217681_at | 0.975 | 1.55E-06 |
| — | 1564789_at | 0.975 | 1.60E-06 |
| LIMA1 | 222457_s_at | 0.975 | 1.64E-06 |
| RHBDL2 | 1554897_s_at | 0.974 | 1.80E-06 |
| ZBP1 | 208087_s_at | 0.974 | 1.87E-06 |
| — | 1563485_at | 0.974 | 1.87E-06 |
| BDKRB2 | 205870_at | 0.974 | 1.87E-06 |
| — | 1561893_at | 0.974 | 1.88E-06 |
| SPRR1B | 205064_at | 0.974 | 1.93E-06 |
| CACNG4 | 221585_at | 0.974 | 2.00E-06 |
| RGS20 | 1569303_s_at | 0.974 | 2.04E-06 |
| CLCA2 | 206166_s_at | 0.974 | 2.04E-06 |
| LGALS9 | 203236_s_at | 0.973 | 2.13E-06 |
| NTN4 | 223315_at | 0.973 | 2.15E-06 |
| TNIP1 | 207196_s_at | 0.973 | 2.22E-06 |
| GPR115 | 237690_at | 0.973 | 2.36E-06 |
| SHH | 207586_at | 0.972 | 2.46E-06 |
| LY6E | 202145_at | 0.972 | 2.46E-06 |
| FAM84A | 234331_s_at | 0.972 | 2.48E-06 |
| LGP2 | 219364_at | 0.972 | 2.63E-06 |
| RPP25 | 219143_s_at | 0.972 | 2.78E-06 |
| GPSN2 | 231556_at | 0.971 | 2.83E-06 |
| CREG1 | 201200_at | 0.971 | 2.91E-06 |
| P2RY2 | 206277_at | 0.971 | 3.00E-06 |
| GRAMD2 | 229616_s_at | 0.971 | 3.06E-06 |
| MFNG | 204152_s_at | 0.971 | 3.08E-06 |
| FLJ33790 | 1553611_s_at | 0.970 | 3.34E-06 |
| MAPK13 | 210059_s_at | 0.970 | 3.48E-06 |
| NELL1 | 206089_at | 0.970 | 3.51E-06 |
| ADM | 202912_at | 0.970 | 3.52E-06 |
| LOC63928 | 206149_at | 0.970 | 3.62E-06 |
| PLAU | 205479_s_at | 0.969 | 3.84E-06 |
| — | 238725_at | 0.969 | 4.04E-06 |
| FCER1G | 1554899_s_at | 0.969 | 4.11E-06 |
| B4GALT5 | 221485_at | 0.969 | 4.13E-06 |
| PLAU | 211668_s_at | 0.968 | 4.28E-06 |
| OTUD1 | 238998_x_at | 0.968 | 4.34E-06 |
| IGSF3 | 1552672_a_at | 0.968 | 4.39E-06 |
| GRHL1 | 222830_at | 0.968 | 4.45E-06 |
| — | 227957_at | 0.968 | 4.53E-06 |
| OTUD1 | 226140_s_at | 0.968 | 4.53E-06 |
| — | 1564294_at | 0.968 | 4.54E-06 |
| MB | 204179_at | 0.968 | 4.55E-06 |
| PYHIN1 | 240413_at | 0.968 | 4.63E-06 |
| LITAF | 200706_s_at | 0.968 | 4.69E-06 |
| FAM83A | 238460_at | 0.967 | 4.80E-06 |
| CRISP3 | 207802_at | 0.967 | 4.87E-06 |
| GABARAPL1 | 208869_s_at | 0.967 | 4.97E-06 |
| HLA-DRA | 208894_at | 0.967 | 5.22E-06 |
| PRKD3 | 222565_s_at | 0.966 | 5.65E-06 |
| S100A8 | 214370_at | 0.966 | 5.67E-06 |
| — | 1565833_at | 0.966 | 5.69E-06 |
| HOMER3 | 204647_at | 0.966 | 5.77E-06 |
| — | 1560960_at | 0.966 | 5.90E-06 |
| DRAM | 218627_at | 0.965 | 6.01E-06 |
| ALPP | 204664_at | 0.965 | 6.14E-06 |
| GBP3 | 223434_at | 0.965 | 6.19E-06 |
| LOC645249 | 236967_at | 0.965 | 6.23E-06 |
| UBE1L | 203281_s_at | 0.965 | 6.37E-06 |
| PTK2 | 207821_s_at | 0.965 | 6.53E-06 |
| PTK2 | 208820_at | 0.965 | 6.62E-06 |
| SH3RF2 | 228892_at | 0.964 | 6.69E-06 |
| CLCA2 | 206165_s_at | 0.964 | 7.06E-06 |
| CTSB | 213275_x_at | 0.964 | 7.41E-06 |
| SLC1A6 | 206882_at | 0.963 | 7.49E-06 |
| CASQ2 | 207317_s_at | 0.963 | 7.53E-06 |
| — | 236346_at | 0.963 | 7.56E-06 |
| EVA1 | 230518_at | 0.963 | 7.66E-06 |
| — | 241207_at | 0.963 | 7.67E-06 |
| C14orf147 | 212460_at | 0.963 | 8.18E-06 |
| — | 234215_at | 0.962 | 8.32E-06 |
| LOC285954 | 1557850_at | 0.962 | 8.63E-06 |
| — | 233293_at | 0.962 | 8.79E-06 |
| LIMA1 | 217892_s_at | 0.962 | 8.86E-06 |
| RIPK4 | 221215_s_at | 0.962 | 8.92E-06 |
| — | 1566481_at | 0.962 | 8.94E-06 |
| KLF3 | 225140_at | 0.962 | 8.99E-06 |
| C1orf58 | 239078_at | 0.961 | 9.28E-06 |
| LOC375295 | 228564_at | 0.961 | 9.41E-06 |
| ATBF1 | 233751_at | 0.961 | 9.73E-06 |
| DHRS9 | 223952_x_at | 0.961 | 9.87E-06 |
| GJA5 | 214466_at | 0.961 | 9.99E-06 |
| JAG2 | 32137_at | 0.961 | 1.00E-05 |
| — | 227210_at | 0.961 | 1.01E-05 |
| PPP1R3D | 204555_s_at | 0.960 | 1.03E-05 |
| GDPD3 | 219722_s_at | 0.960 | 1.03E-05 |
| — | 1561967_at | 0.960 | 1.05E-05 |
| KAL1 | 205206_at | 0.960 | 1.06E-05 |
| ARTS-1 | 214012_at | 0.960 | 1.06E-05 |
| GRAMD2 | 230828_at | 0.960 | 1.08E-05 |
| IRF1 | 202531_at | 0.960 | 1.08E-05 |
| RNASE7 | 233488_at | 0.960 | 1.09E-05 |
| OSR2 | 213568_at | 0.960 | 1.09E-05 |
| DSC3 | 206033_s_at | 0.960 | 1.10E-05 |
| — | 231512_at | 0.960 | 1.11E-05 |
| NPR3 | 219790_s_at | 0.959 | 1.13E-05 |
| CFHR2 | 206910_x_at | 0.959 | 1.20E-05 |
| ARTN | 210237_at | 0.959 | 1.20E-05 |
| LRRC8B | 242038_at | 0.958 | 1.24E-05 |
| LOC346887 | 235205_at | 0.958 | 1.24E-05 |
| IGF1R | 203627_at | 0.958 | 1.25E-05 |
| RARB | 205080_at | 0.958 | 1.26E-05 |
| JAG2 | 209784_s_at | 0.958 | 1.26E-05 |
| FUT3 | 214088_s_at | 0.958 | 1.28E-05 |
| MARK1 | 226653_at | 0.958 | 1.30E-05 |
| PSG7 | 205602_x_at | 0.958 | 1.35E-05 |
| WFIKKN1 | 1552811_at | 0.957 | 1.42E-05 |
| CAPZA1 | 217392_at | 0.957 | 1.43E-05 |
| IL7 | 206693_at | 0.956 | 1.52E-05 |
| LDB3 | 213717_at | 0.956 | 1.52E-05 |
| — | 233991_at | 0.956 | 1.54E-05 |
| KLK6 | 204733_at | 0.956 | 1.56E-05 |
| LITAF | 200704_at | 0.956 | 1.57E-05 |
| — | 243348_at | 0.956 | 1.58E-05 |
| INHBA | 210511_s_at | 0.956 | 1.59E-05 |
| ABCA12 | 215465_at | 0.956 | 1.60E-05 |
| C1orf21 | 237098_at | 0.956 | 1.61E-05 |
| CTSB | 227961_at | 0.956 | 1.62E-05 |
| FAP | 209955_s_at | 0.955 | 1.66E-05 |
| CARD14 | 232608_x_at | 0.955 | 1.69E-05 |
| IFIH1 | 1555464_at | 0.954 | 1.78E-05 |
| HOMER3 | 215489_x_at | 0.954 | 1.82E-05 |
| RHBDL2 | 1552502_s_at | 0.954 | 1.83E-05 |
| NO145 | 236337_at | 0.954 | 1.85E-05 |
| BCAR1 | 232442_at | 0.954 | 1.87E-05 |
| IFIH1 | 216020_at | 0.954 | 1.87E-05 |
| C14orf147 | 213508_at | 0.954 | 1.90E-05 |
| ANKRD22 | 238439_at | 0.952 | 2.12E-05 |
| — | 239452_at | 0.952 | 2.13E-05 |
| TMEM16A | 218804_at | 0.952 | 2.20E-05 |
| C5orf23 | 219054_at | 0.952 | 2.22E-05 |
| ARTN | 216052_x_at | 0.952 | 2.24E-05 |
| FAM110A | 226584_s_at | 0.951 | 2.36E-05 |
| SRCAP | 213667_at | 0.951 | 2.39E-05 |
| HILS1 | 231229_at | 0.951 | 2.41E-05 |
| ANKRD15 | 238789_at | 0.951 | 2.44E-05 |
| — | 1561924_at | 0.950 | 2.52E-05 |
| EPN3 | 223895_s_at | 0.950 | 2.53E-05 |
| LMOD3 | 1555567_s_at | 0.950 | 2.54E-05 |
| — | 233088_at | 0.950 | 2.55E-05 |
| BLNK | 207655_s_at | 0.950 | 2.57E-05 |
| GABARAPL1 /// GABARAPL3 | 211458_s_at | 0.950 | 2.57E-05 |
| CARD14 | 220599_s_at | 0.950 | 2.61E-05 |
| TIGD2 | 229983_at | 0.950 | 2.62E-05 |
| KLF3 | 225133_at | 0.950 | 2.63E-05 |
| SOX7 | 224013_s_at | 0.950 | 2.64E-05 |
| TRIM6 | 223599_at | 0.950 | 2.65E-05 |
| LOC285740 | 1556859_a_at | 0.949 | 2.68E-05 |
| PTK2B | 203110_at | 0.949 | 2.80E-05 |
| SFN | 209260_at | 0.949 | 2.86E-05 |
| FREM2 | 230964_at | 0.948 | 2.91E-05 |
| PLEKHF2 | 218640_s_at | 0.948 | 2.93E-05 |
| UBL3 | 201534_s_at | 0.948 | 2.98E-05 |
| CLEC7A | 1554406_a_at | 0.948 | 3.02E-05 |
| LOC57228 | 209679_s_at | 0.948 | 3.05E-05 |
| — | 232254_at | 0.947 | 3.16E-05 |
| NFKBIA | 201502_s_at | 0.947 | 3.27E-05 |
| PDE5A | 227088_at | 0.947 | 3.29E-05 |
| — | 1559483_at | 0.946 | 3.40E-05 |
| DMRTB1 | 240313_at | 0.946 | 3.40E-05 |
| WBP5 | 217975_at | 0.946 | 3.43E-05 |
| KLF4 | 220266_s_at | 0.946 | 3.44E-05 |
| — | 235732_at | 0.946 | 3.47E-05 |
| SDC1 | 201287_s_at | 0.946 | 3.55E-05 |
| IKZF2 | 231929_at | 0.945 | 3.63E-05 |
| HLA-DQB1 | 210747_at | 0.945 | 3.71E-05 |
| PSMB10 | 202659_at | 0.945 | 3.77E-05 |
| RAB20 | 219622_at | 0.945 | 3.77E-05 |
| XDH | 241994_at | 0.945 | 3.86E-05 |
| PRKD3 | 218236_s_at | 0.945 | 3.86E-05 |
| ETS2 | 201328_at | 0.944 | 3.90E-05 |
| FGFBP1 | 205014_at | 0.944 | 3.90E-05 |
| RIPK4 | 234730_s_at | 0.944 | 3.90E-05 |
| SEMA4A | 219259_at | 0.944 | 4.05E-05 |
| — | AFFX-r2-Bs-dap-3_at | 0.944 | 4.12E-05 |
| SLC2A9 | 219991_at | 0.944 | 4.13E-05 |
| B3GALT2 | 210121_at | 0.943 | 4.26E-05 |
| ZNHIT4 | 221251_x_at | 0.943 | 4.29E-05 |
| IVD | 203681_at | 0.943 | 4.40E-05 |
| STS | 203768_s_at | 0.943 | 4.40E-05 |
| RUFY2 | 1569630_a_at | 0.942 | 4.59E-05 |
| — | 1558890_at | 0.942 | 4.72E-05 |
| — | 1563462_at | 0.941 | 4.82E-05 |
| DLL1 | 224215_s_at | 0.941 | 4.89E-05 |
| GM2A | 215891_s_at | 0.941 | 4.95E-05 |
| SFN | 33323_r_at | 0.941 | 5.02E-05 |
| GGT6 | 236225_at | 0.940 | 5.15E-05 |
| PTGER4 | 204897_at | 0.940 | 5.18E-05 |
| IFNA8 | 207932_at | 0.940 | 5.23E-05 |
| C18orf54 | 229442_at | 0.940 | 5.31E-05 |
| — | 239661_at | 0.940 | 5.35E-05 |
| HOXD13 | 207398_at | 0.939 | 5.52E-05 |
| SSX2IP | 203016_s_at | 0.939 | 5.55E-05 |
| OAS1 | 205552_s_at | 0.939 | 5.66E-05 |
| HES2 | 231928_at | 0.939 | 5.79E-05 |
| TRIM7 | 1554735_a_at | 0.938 | 5.87E-05 |
| FLJ41603 | 227717_at | 0.938 | 5.90E-05 |
| RERG | 227758_at | 0.938 | 5.97E-05 |
| — | 1556740_at | 0.938 | 6.01E-05 |
| PTAFR | 211661_x_at | 0.938 | 6.04E-05 |
| GPR110 | 235988_at | 0.938 | 6.10E-05 |
| PTK6 | 1553114_a_at | 0.937 | 6.22E-05 |
| TLR3 | 206271_at | 0.937 | 6.22E-05 |
| MGAT3 | 208058_s_at | 0.937 | 6.48E-05 |
| EHD2 | 221870_at | 0.937 | 6.49E-05 |
| NDRG2 | 206453_s_at | 0.937 | 6.52E-05 |
| — | 240178_at | 0.936 | 6.74E-05 |
| — | 242397_at | 0.936 | 6.79E-05 |
| PSG9 | 209594_x_at | 0.936 | 6.85E-05 |
| PLEKHF2 | 222699_s_at | 0.936 | 6.87E-05 |
| MBD2 | 202484_s_at | 0.936 | 6.91E-05 |
| NLRP4 | 242334_at | 0.936 | 6.91E-05 |
| IRF6 | 1552478_a_at | 0.935 | 7.02E-05 |
| BACE2 | 217867_x_at | 0.935 | 7.06E-05 |
| NRAP | 207089_at | 0.935 | 7.11E-05 |
| ASXL3 | 232838_at | 0.935 | 7.19E-05 |
| FAM84A /// LOC653602 | 225667_s_at | 0.935 | 7.23E-05 |
| MGC9712 | 1558281_a_at | 0.935 | 7.26E-05 |
| — | 233130_at | 0.935 | 7.38E-05 |
| CTSD | 200766_at | 0.934 | 7.47E-05 |
| DSC3 | 206032_at | 0.934 | 7.59E-05 |
| JUNB | 201473_at | 0.934 | 7.65E-05 |
| STK3 | 204068_at | 0.934 | 7.89E-05 |
| TMC1 | 1564591_a_at | 0.933 | 7.91E-05 |
| OR10D3P | 1567252_at | 0.933 | 7.92E-05 |
| TMBIM1 | 217730_at | 0.933 | 8.08E-05 |
| B4GALT5 | 221484_at | 0.933 | 8.22E-05 |
| DENND4C | 226867_at | 0.933 | 8.26E-05 |
| MAP3K7IP3 | 1552927_at | 0.933 | 8.27E-05 |
| — | 229670_at | 0.932 | 8.42E-05 |
| — | 232657_at | 0.932 | 8.60E-05 |
| BACE2 | 222446_s_at | 0.932 | 8.85E-05 |
| MMP14 | 202828_s_at | 0.931 | 8.94E-05 |
| — | 229937_x_at | 0.931 | 8.98E-05 |
| RGS12 | 205823_at | 0.931 | 9.06E-05 |
| GNA15 | 205349_at | 0.931 | 9.06E-05 |
| TP73L | 211834_s_at | 0.931 | 9.22E-05 |
| RYR1 | 205485_at | 0.930 | 9.65E-05 |
| MMP14 | 202827_s_at | 0.930 | 9.66E-05 |
| — | 236101_at | 0.930 | 9.70E-05 |
| KIAA1815 | 218342_s_at | 0.930 | 9.90E-05 |
| SPINK5 | 205185_at | 0.930 | 9.90E-05 |
| — | 244060_at | 0.929 | 9.95E-05 |
| CTSS | 202901_x_at | 0.929 | 9.96E-05 |
| NPR3 | 219789_at | 0.929 | .000102378 |
| SP6 | 228975_at | 0.929 | .00010341 |
| POLR3K | 222766_at | 0.929 | .000103622 |
| APOL6 | 1557236_at | 0.929 | .000104435 |
| BTN3A2 | 212613_at | 0.929 | .000104486 |
| NCOA3 | 209061_at | 0.928 | .000105466 |
| PSG3 | 215821_x_at | 0.928 | .000105592 |
| SH3YL1 | 1554198_at | 0.928 | .000105928 |
| C21orf122 | 223768_at | 0.928 | .000105953 |
| LOC388494 | 233064_at | 0.928 | .000110413 |
| GABARAPL1 | 208868_s_at | 0.927 | .000111154 |
| SSX2IP | 203015_s_at | 0.927 | .000114242 |
| SAMD9 | 228531_at | 0.927 | .000114344 |
| CAB39 | 224311_s_at | 0.927 | .000114739 |
| — | 235247_at | 0.927 | .00011518 |
| SPHK1 | 219257_s_at | 0.927 | .000115318 |
| KLF3 | 219657_s_at | 0.927 | .000115535 |
| LINCR | 232593_at | 0.926 | .000116921 |
| FXYD3 | 202488_s_at | 0.926 | .000117352 |
| S100P | 204351_at | 0.926 | .000117759 |
| ETS2 | 201329_s_at | 0.926 | .000117996 |
| C12orf60 | 243056_at | 0.926 | .000118562 |
| OVOL1 | 229396_at | 0.926 | .000118729 |
| GM2A | 212737_at | 0.926 | .000118844 |
| GM2A | 35820_at | 0.926 | .000119455 |
| MYLIP | 220319_s_at | 0.926 | .000119997 |
| C2orf33 | 223091_x_at | 0.926 | .000121373 |
| RAPGEFL1 | 218657_at | 0.926 | .000121704 |
| ACTL8 | 214957_at | 0.926 | .00012171 |
| UBE2G1 | 226005_at | 0.926 | .000122147 |
| BDKRB1 | 207510_at | 0.926 | .000122879 |
| FAM62B | 1555830_s_at | 0.925 | .000123188 |
| ETHE1 | 204034_at | 0.925 | .000123421 |
| EMP2 | 225079_at | 0.925 | .000123781 |
| CD82 | 203904_x_at | 0.925 | .000124273 |
| EHD2 | 45297_at | 0.925 | .000124427 |
| — | 242199_at | –0.925 | .00012838 |
| SNN | 218032_at | 0.925 | .000128839 |
| FLJ20366 | 218692_at | 0.924 | .000131103 |
| DENND4C | 205684_s_at | 0.924 | .000133131 |
| VAV3 | 224221_s_at | 0.924 | .000134543 |
| STS | 203767_s_at | 0.923 | .0001371 |
| NXT1 | 218708_at | 0.923 | .000137148 |
| CTSH | 202295_s_at | 0.923 | .000137216 |
| — | 229648_at | 0.923 | .000140509 |
| CSF2RA | 211286_x_at | 0.923 | .000141116 |
| — | 230751_at | 0.923 | .000141539 |
| TBC1D1 | 1569566_at | 0.923 | .000143183 |
| C1orf46 | 216718_at | 0.923 | .000143428 |
| GCM1 | 206269_at | 0.922 | .000145327 |
| — | 1559166_at | 0.922 | .000146825 |
| FAM62B | 224699_s_at | 0.922 | .000147643 |
| MDGA1 | 238543_x_at | 0.922 | .000150952 |
| LOC92017 | 225608_at | 0.921 | .000152311 |
| NDUFV1 | 227795_at | 0.921 | .000153387 |
| LOC728056 /// LOC731035 | 1553949_at | 0.920 | .000160349 |
| STAP2 | 221610_s_at | 0.920 | .000161932 |
| FAT3 | 1560490_at | 0.920 | .000162965 |
| — | 220726_at | 0.919 | .000166674 |
| ARFGEF1 | 202955_s_at | 0.919 | .000167288 |
| RAB26 | 50965_at | 0.919 | .00016895 |
| NCOA3 | 211352_s_at | 0.919 | .000170407 |
| — | 242321_at | 0.919 | .000171758 |
| ZNF706 | 218059_at | 0.919 | .000174359 |
| LOC439949 | 232001_at | 0.918 | .000175399 |
| C14orf135 | 235187_s_at | 0.918 | .000178396 |
| RAB9A | 221808_at | 0.918 | .000181206 |
| NCOA3 | 209060_x_at | 0.918 | .000183002 |
| ASAH1 | 213902_at | 0.917 | .000186163 |
| — | 235079_at | 0.917 | .000189672 |
| DLX3 | 231778_at | 0.917 | .000190329 |
| SAT1 | 210592_s_at | 0.917 | .000190588 |
| RIF1 | 214872_at | 0.917 | .000191633 |
| C1QB | 202953_at | 0.916 | .000195075 |
| MTA3 | 223311_s_at | 0.915 | .000201409 |
| TCIRG1 | 204158_s_at | 0.915 | .000201717 |
| LOC729013 | 235010_at | 0.915 | .000202186 |
| FAM13A1 | 202972_s_at | 0.915 | .000203 |
| C18orf54 | 1553651_at | 0.915 | .000205188 |
| LOC729659 /// LOC730278 /// LOC730558 | 208540_x_at | 0.915 | .000207005 |
| SLC2A9 | 232678_at | 0.915 | .000209009 |
| ORF1 | 234806_at | 0.915 | .000209084 |
| GM2A | 33646_g_at | 0.915 | .000209102 |
| MGC40069 | 243602_at | 0.915 | .000209171 |
| ZNF704 | 1558941_at | 0.915 | .000210222 |
| DST | 216918_s_at | 0.914 | .000211105 |
| AIM1 | 212543_at | 0.914 | .000218021 |
| PAK6 | 1555310_a_at | 0.914 | .00021839 |
| PRKD3 | 211084_x_at | 0.914 | .000219882 |
| CASP1 | 211367_s_at | 0.913 | .00022067 |
| LAMB4 | 216622_at | 0.913 | .000220762 |
| — | 1570221_at | 0.913 | .000224456 |
| DKFZp547J222 | 234769_at | 0.913 | .000227197 |
| — | 229716_at | 0.913 | .000227531 |
| C12orf60 | 229888_at | 0.913 | .000227923 |
| — | 1567059_at | 0.913 | .000228919 |
| — | 233055_at | 0.913 | .000229293 |
| ELF2 | 210361_s_at | 0.913 | .000229426 |
| IL4R | 203233_at | 0.913 | .000229836 |
| — | 1557669_at | 0.912 | .000232684 |
| SSX2IP | 203017_s_at | 0.912 | .000234383 |
| C21orf84 | 239968_at | 0.912 | .000234914 |
| TRPS1 | 224218_s_at | 0.912 | .000235419 |
| CFH | 213800_at | 0.912 | .00023664 |
| TNKS1BP1 | 224792_at | 0.912 | .000240558 |
| IKBKB | 211027_s_at | 0.912 | .000240597 |
| STS | 203770_s_at | 0.912 | .000240703 |
| SHOX2 | 208443_x_at | 0.911 | .000241466 |
| BRWD1 | 214820_at | 0.911 | .000241537 |
| — | 1562245_a_at | 0.911 | .000242526 |
| SOX7 | 228698_at | 0.911 | .000243326 |
| SAT1 | 213988_s_at | 0.911 | .00024655 |
| FAM62B | 1558511_s_at | 0.911 | .000249443 |
| FAM125A | 1556643_at | 0.911 | .000250042 |
| CEBPB | 212501_at | 0.911 | .000250933 |
| APOL6 | 241869_at | 0.911 | .000251108 |
| MTMR1 | 213511_s_at | 0.910 | .000252239 |
| CNGB1 | 207342_at | 0.910 | .000259111 |
| HNRNPG-T | 207208_at | 0.910 | .000261409 |
| — | 243813_at | 0.909 | .000262964 |
| SFN | 33322_i_at | 0.909 | .000267629 |
| C15orf48 | 223484_at | 0.909 | .000268805 |
| PIAS1 | 217864_s_at | 0.909 | .000272514 |
| EMP2 | 204975_at | 0.909 | .000273728 |
| C10orf47 | 230051_at | 0.908 | .000281836 |
| HLA-DRB1 | 221491_x_at | 0.908 | .000283225 |
| MFSD3 | 227296_at | 0.908 | .000283377 |
| TRPS1 | 234351_x_at | 0.908 | .000285863 |
| UBA7 | 1294_at | 0.907 | .000287114 |
| KCNN4 | 204401_at | 0.907 | .000287492 |
| SERPIND1 | 205576_at | 0.907 | .000288697 |
| NSMAF | 232149_s_at | 0.907 | .000293631 |
| EPAS1 | 200878_at | 0.907 | .000296617 |
| — | 241440_at | 0.906 | .000299286 |
| HGFAC | 207027_at | 0.906 | .00030017 |
| SNCG | 209877_at | 0.906 | .00030041 |
| FLJ12684 | 219987_at | 0.906 | .000302935 |
| JARID1B | 201548_s_at | 0.905 | .00031118 |
| SYTL4 | 229991_s_at | 0.905 | .000311748 |
| MOBKL2B | 219265_at | 0.905 | .000317105 |
| ARTN | 207675_x_at | 0.905 | .000321258 |
| — | 234652_at | 0.904 | .000326503 |
| EGFR | 201984_s_at | 0.904 | .000327301 |
| CFH /// CFHR1 | 215388_s_at | 0.904 | .00033111 |
| — | 223366_at | 0.904 | .000332981 |
| C20orf42 | 60474_at | 0.904 | .000335928 |
| SIX5 | 241822_at | 0.903 | .000337412 |
| PDK4 | 1562321_at | 0.903 | .00033864 |
| DST | 204455_at | 0.903 | .000339003 |
| — | 1562158_at | 0.903 | .000341269 |
| — | 244107_at | 0.903 | .0003415 |
| ANKRD2 | 221232_s_at | 0.903 | .000346342 |
| CAB39 | 217873_at | 0.903 | .000348325 |
| — | 238902_at | 0.903 | .000348751 |
| RAP2B | 214488_at | 0.903 | .000350175 |
| SSX2IP | 203018_s_at | 0.902 | .000351269 |
| FLJ33630 | 228686_at | 0.902 | .000358114 |
| — | 236297_at | 0.902 | .000359169 |
| UBL3 | 201535_at | 0.902 | .000364721 |
| DGKA | 211272_s_at | 0.901 | .000366856 |
| ENOX1 | 219501_at | 0.901 | .000367074 |
| MR1 | 207566_at | 0.901 | .000371433 |
| PAK6 | 219461_at | 0.901 | .000373233 |
| CLEC2B | 209732_at | 0.901 | .000377605 |
| CCNYL1 | 228810_at | 0.901 | .000378212 |
| EVA1 | 203779_s_at | 0.900 | .000384346 |
| C12orf25 | 224039_at | 0.900 | .000384356 |
| TMC8 | 236554_x_at | 0.900 | .000384732 |
| — | 1560721_at | 0.900 | .000387435 |
| PSG5 | 204830_x_at | 0.900 | .000387467 |
| APOL6 | 219716_at | 0.900 | .00039114 |
| TP73L | 207382_at | 0.899 | .000396604 |
| C4orf28 | 235260_s_at | 0.899 | .000396996 |
| PRSS22 | 205847_at | 0.899 | .000399453 |
| MAP3K7IP3 | 227357_at | 0.899 | .00040365 |
| ARPC2 | 207988_s_at | 0.899 | .000405133 |
| — | 230356_at | 0.898 | .000410689 |
| PLXDC2 | 227276_at | 0.898 | .000415876 |
| PSMB9 | 204279_at | 0.898 | .000416619 |
| SDC1 | 201286_at | 0.898 | .000419102 |
| BRE | 1568768_s_at | 0.898 | .000420968 |
| — | 1555852_at | 0.898 | .000423408 |
| — | 1556496_a_at | 0.898 | .000424191 |
| EFNA1 | 202023_at | 0.898 | .000424845 |
| EMP2 | 225078_at | 0.897 | .000426223 |
| C1orf107 | 214193_s_at | 0.897 | .000427363 |
| JARID1B | 201549_x_at | 0.897 | .000429935 |
| GPR37 | 209631_s_at | 0.897 | .000431219 |
| — | 1560109_s_at | 0.897 | .000434149 |
| ALOX5 | 204446_s_at | 0.896 | .000449923 |
| LYPD3 | 204952_at | 0.896 | .00045334 |
| KIAA0251 | 1560014_s_at | 0.896 | .000453858 |
| HYDIN2 | 1563529_at | 0.896 | .000454943 |
| C9orf40 | 218904_s_at | 0.896 | .00045522 |
| PRO2012 | 1553546_at | 0.895 | .000459541 |
| PSG6 | 209738_x_at | 0.895 | .000459644 |
| ARNTL | 209824_s_at | 0.895 | .000461495 |
| MCTP2 | 1554833_at | 0.895 | .000465398 |
| RY1 | 212438_at | –0.895 | .000468611 |
| CCND2 | 200952_s_at | 0.895 | .000474268 |
| LILRB3 | 210784_x_at | 0.894 | .000477113 |
| — | 230606_at | 0.894 | .000480607 |
| S100A11 | 200660_at | 0.894 | .0004807 |
| PSMB8 | 209040_s_at | 0.894 | .000481605 |
| LOC55565 | 242704_at | 0.894 | .000485747 |
| EPN3 | 220318_at | 0.894 | .000491211 |
| IGH@ /// IGHD /// IGHG1 /// IGHV4-31 | 217198_x_at | 0.894 | .000491307 |
| KIAA1815 | 222603_at | 0.894 | .000491501 |
| — | 244035_at | 0.893 | .000494278 |
| RPP25 | 223415_at | 0.893 | .000495834 |
| — | 215372_x_at | 0.893 | .000500395 |
| STON2 | 235852_at | 0.893 | .00050174 |
| DNAH14 /// LOC127602 | 1567862_at | 0.893 | .000510256 |
| WEE1 | 215711_s_at | 0.892 | .000512917 |
| NCOA3 | 207700_s_at | 0.892 | .000514313 |
| C10orf118 | 229399_at | 0.892 | .000515285 |
| ARPC2 | 213513_x_at | 0.892 | .000518686 |
| NLRP14 | 1553523_at | 0.892 | .00052317 |
| C7orf45 | 1553330_at | 0.892 | .000525445 |
| PTPN22 | 206060_s_at | 0.892 | .000527274 |
| HSPB1 | 201841_s_at | 0.891 | .000531302 |
| HAR1A | 1557098_s_at | 0.891 | .000537285 |
| ADRB1 | 229309_at | 0.891 | .000539234 |
| MAP3K7IP3 | 1552928_s_at | 0.891 | .000539976 |
| MMP28 | 239273_s_at | 0.891 | .000544681 |
| CXCL2 | 1569203_at | 0.891 | .000548695 |
| FCAMR | 231496_at | 0.891 | .0005498 |
| — | 242708_at | –0.890 | .000551952 |
| SNN | 218033_s_at | 0.890 | .00055469 |
| MGC42157 | 239104_at | 0.890 | .00056834 |
| CROCC | 216419_at | 0.889 | .000570934 |
| ADRA1A | 211492_s_at | 0.889 | .000571963 |
| PLXNA2 | 227032_at | 0.889 | .000572623 |
| MOBKL2B | 229568_at | 0.889 | .00058339 |
| TAOK3 | 221508_at | 0.889 | .000584789 |
| NMI | 203964_at | 0.888 | .000592474 |
| — | 236429_at | 0.888 | .000593139 |
| MYCL1 | 214058_at | 0.888 | .000593393 |
| TH | 208291_s_at | 0.888 | .000597319 |
| CRB1 | 244403_at | 0.888 | .000597471 |
| — | 229296_at | 0.888 | .000600431 |
| LRP4 | 212850_s_at | 0.888 | .000600982 |
| WNK2 | 1560866_at | 0.887 | .000611796 |
| RICS | 203431_s_at | 0.887 | .000612614 |
| C10orf54 | 225373_at | 0.887 | .000614576 |
| PPP1R9A | 228494_at | –0.887 | .000624714 |
| KCNAB2 | 211791_s_at | 0.886 | .000640257 |
| — | 227184_at | 0.886 | .000647715 |
| USP31 | 226033_at | 0.885 | .00065659 |
| — | 1569740_at | 0.885 | .000659072 |
| SLC26A1 | 220733_at | 0.885 | .000661677 |
| TPP1 | 214195_at | 0.885 | .000661918 |
| — | 1561240_at | 0.885 | .000662579 |
| NEUROG2 | 215632_at | 0.884 | .000676861 |
| KIAA1614 | 215367_at | 0.884 | .000679788 |
| NPAL2 | 220128_s_at | 0.884 | .000682334 |
| TIGD5 | 229758_at | 0.884 | .00068423 |
| ARFGEF1 | 216266_s_at | 0.884 | .000686889 |
| PSTPIP2 | 219938_s_at | 0.884 | .000687695 |
| EVA1 | 203780_at | 0.883 | .000700832 |
| FAM46B | 229518_at | 0.883 | .000701527 |
| — | 1565929_s_at | 0.883 | .000701793 |
| — | 229641_at | 0.883 | .000713149 |
| AMOTL1 | 225459_at | 0.883 | .000714903 |
| HP /// HPR | 208470_s_at | 0.883 | .000717757 |
| LOC550113 | 1556992_at | 0.883 | .000719801 |
| FLJ38377 | 1553350_at | 0.882 | .00072515 |
| ATP8B1 | 214594_x_at | 0.882 | .000728856 |
| YWHAZ | 200639_s_at | 0.882 | .000731689 |
| PTPN14 | 205503_at | 0.882 | .000736584 |
| TKT | 228205_at | 0.881 | .000747251 |
| CBFA2T3 | 208056_s_at | 0.881 | .000747961 |
| CCBP2 | 1559432_at | 0.881 | .000749939 |
| ZNF331 | 227613_at | 0.881 | .000750519 |
| RAB26 | 219562_at | 0.881 | .000752827 |
| — | 1568870_at | 0.881 | .000753617 |
| FBLN1 | 201787_at | 0.881 | .00075382 |
| RABEP2 | 74694_s_at | 0.881 | .000753872 |
| ZNF704 | 241963_at | 0.881 | .000754828 |
| — | 233683_at | 0.881 | .000762247 |
| RDX | 212397_at | 0.881 | .000765416 |
| KIAA0317 | 244137_at | 0.881 | .000765954 |
| CSF2RA | 210340_s_at | 0.881 | .000770359 |
| ATP6V1E2 | 1552286_at | 0.880 | .000771003 |
| NRXN2 | 209982_s_at | 0.880 | .000773288 |
| ZBED1 | 203043_at | 0.880 | .000776136 |
| ARNTL | 210971_s_at | 0.880 | .000780424 |
| — | 240844_at | 0.880 | .000780678 |
| MYLIP | 228098_s_at | 0.880 | .00078139 |
| SERPINB5 | 204855_at | 0.880 | .000789504 |
| HOXD13 | 207397_s_at | 0.880 | .000792999 |
| CTSS | 202902_s_at | 0.879 | .000799363 |
| RPS24 | 1555878_at | 0.879 | .00080173 |
| — | 237547_at | 0.879 | .00080228 |
| PDE5A | 1553175_s_at | 0.879 | .000803359 |
| CABLES1 | 225532_at | 0.879 | .000809243 |
| SLC16A3 | 202856_s_at | 0.879 | .000811605 |
| CTNND2 | 209618_at | 0.878 | .000824556 |
| DHRS9 | 224009_x_at | 0.878 | .000827211 |
| NUP133 | 233421_s_at | 0.878 | .000830936 |
| CSF2RA | 211287_x_at | 0.878 | .000843121 |
| TRAF3IP3 | 213888_s_at | 0.878 | .000843574 |
| — | 231259_s_at | 0.878 | .000844385 |
| — | 1565834_a_at | 0.877 | .000849562 |
| LOC284274 | 1556288_at | 0.877 | .00085111 |
| PDGFA | 205463_s_at | 0.877 | .000862145 |
| C11orf17 | 242515_x_at | 0.877 | .000868138 |
| REL | 206036_s_at | 0.877 | .00087303 |
| ZNF83 | 221645_s_at | 0.877 | .000873261 |
| CNR1 | 1560225_at | –0.877 | .000873522 |
| REC8L1 | 229536_at | 0.876 | .000877735 |
| — | 238305_at | 0.876 | .00088085 |
| IRF2BP2 | 225854_x_at | 0.876 | .000881005 |
| TAPBPL | 218747_s_at | 0.876 | .000886154 |
| LOC284454 | 1555847_a_at | 0.876 | .000889104 |
| NSMAF | 1558775_s_at | 0.876 | .000892381 |
| GIYD1 /// GIYD2 /// SULT1A3 /// SULT1A4 | 233334_x_at | 0.876 | .000892407 |
| COL23A1 | 229168_at | 0.876 | .00089859 |
| FRY | 204072_s_at | 0.876 | .000899526 |
| — | 236489_at | 0.876 | .000900246 |
| VPS28 | 218679_s_at | 0.875 | .000905948 |
| — | 1559800_a_at | 0.875 | .00090678 |
| — | 233356_at | 0.875 | .000915682 |
| CACNA1C | 242973_at | 0.875 | .000918358 |
| GIYD1 /// GIYD2 | 218317_x_at | 0.875 | .000923065 |
| BTN3A2 | 209846_s_at | 0.874 | .000932479 |
| — | 217220_at | 0.874 | .000933169 |
| MYO1B | 212365_at | 0.874 | .000943197 |
| FBXO32 | 225803_at | 0.874 | .000950496 |
| C20orf42 | 218796_at | 0.874 | .000954459 |
| CABP3 /// CABP5 | 221160_s_at | 0.873 | .00096705 |
| FLJ39739 | 1556456_at | 0.873 | .000971118 |
| MAPKAP1 | 229845_at | 0.873 | .000979896 |
| DOK6 | 241729_at | 0.873 | .000981178 |
| ZHX1 | 223214_s_at | 0.873 | .000985554 |
| PHLPP | 212719_at | 0.872 | .000995107 |
| TTC33 | 219421_at | 0.872 | .00100281 |
| JARID1B | 211202_s_at | 0.872 | .001012586 |
| — | 222303_at | 0.872 | .001014155 |
| PCGF1 | 210023_s_at | 0.872 | .001017842 |
| NDRG2 | 214279_s_at | 0.871 | .0010221 |
| SLC9A9 | 242587_at | 0.871 | .001028576 |
| — | 1569270_at | 0.871 | .001032063 |
| — | 236228_at | 0.871 | .001034653 |
| — | 241126_at | 0.871 | .001038633 |
| C2orf33 | 223354_x_at | 0.871 | .001043545 |
| MOBKL2B | 226844_at | 0.871 | .001045608 |
| CCNYL1 | 227280_s_at | 0.871 | .001047352 |
| — | 1562669_at | 0.870 | .001059319 |
| BCL9L | 228065_at | 0.870 | .001063061 |
| PAQR7 | 242123_at | 0.870 | .001071001 |
| GPR175 | 218855_at | 0.870 | .001076951 |
| C9orf14 | 1559292_s_at | 0.869 | .001086056 |
| KRT9 | 208188_at | 0.869 | .001090476 |
| PVRL1 | 225211_at | 0.869 | .001103789 |
| VAV3 | 218807_at | 0.869 | .001106499 |
| — | 239817_at | 0.869 | .00110947 |
| FRAP1 | 215381_at | 0.869 | .001112727 |
| — | 215662_at | 0.868 | .001113304 |
| SMYD2 | 212922_s_at | 0.868 | .001124003 |
| BTG1 | 200920_s_at | 0.868 | .001127037 |
| THSD1 /// THSD1P | 219477_s_at | 0.868 | .001131878 |
| — | 233692_at | 0.868 | .001137789 |
| ICMT | 1568728_s_at | 0.867 | .001149115 |
| EFEMP1 | 201843_s_at | 0.867 | .001166972 |
| KRT19 | 228491_at | 0.867 | .001169292 |
| MARVELD1 | 234917_at | 0.866 | .001182725 |
| — | 235752_at | 0.866 | .001187297 |
| ITGA6 | 215177_s_at | 0.866 | .001196924 |
| NFIL3 | 203574_at | 0.866 | .00120141 |
| ALDH3B2 | 204942_s_at | 0.864 | .001258136 |
| LAMB1 | 201505_at | 0.864 | .001261498 |
| IGF1R | 203628_at | 0.864 | .001263989 |
| SAT1 | 203455_s_at | 0.864 | .00127467 |
| CTNND1 | 1557944_s_at | 0.864 | .001283223 |
| — | 231979_at | 0.863 | .001286538 |
| GRHL1 | 1552685_a_at | 0.863 | .001288051 |
| MEG3 | 210795_s_at | 0.863 | .001298715 |
| — | 241166_at | 0.862 | .001324378 |
| RERE | 1557349_at | 0.862 | .001329004 |
| ECAT1 | 231474_at | 0.862 | .001332501 |
| UBE2G1 | 209142_s_at | 0.862 | .001334267 |
| — | 227765_at | 0.862 | .001335945 |
| — | 230711_at | 0.861 | .001358259 |
| IBRDC2 | 235549_at | 0.861 | .001372554 |
| PAG1 | 225622_at | 0.861 | .001394496 |
| WEE1 | 212533_at | 0.860 | .001407603 |
| C8orf56 | 1554228_a_at | 0.860 | .001407979 |
| FBXW7 | 218751_s_at | 0.860 | .001408415 |
| — | 1564620_at | 0.860 | .001427892 |
| — | 1561419_at | 0.859 | .001439943 |
| HBB | 217232_x_at | 0.859 | .001457139 |
| MYLIP | 223130_s_at | 0.859 | .001463404 |
| HERC4 | 225989_at | 0.859 | .001466417 |
| — | 240811_at | 0.858 | .001478301 |
| FUT6 | 210398_x_at | 0.858 | .0014839 |
| — | 1555982_at | 0.858 | .001488229 |
| HOXD13 | 236681_at | 0.858 | .001490771 |
| CIT | 242872_at | 0.858 | .001495072 |
| TMCO1 | 211098_x_at | –0.858 | .001496216 |
| PTK2B | 203111_s_at | 0.858 | .00149931 |
| PAG1 | 225626_at | 0.857 | .001517918 |
| RHOC | 200885_at | 0.857 | .001525723 |
| — | 1557551_at | 0.857 | .001526948 |
| TWIST2 | 229404_at | 0.857 | .001533674 |
| MPP7 | 238778_at | 0.857 | .001541364 |
| VAV3 | 218806_s_at | 0.857 | .001548536 |
| — | 239587_at | 0.857 | .001548678 |
| NDRG1 | 200632_s_at | 0.856 | .001561433 |
| SLC1A3 | 202800_at | 0.856 | .001562445 |
| ASPM | 239002_at | 0.856 | .001563223 |
| ZC3H11A | 205788_s_at | 0.856 | .001573965 |
| LHX6 | 224556_s_at | 0.856 | .00157495 |
| INHBB | 205258_at | 0.856 | .001585332 |
| — | 1561313_at | 0.855 | .001607113 |
| SOX13 | 209736_at | 0.855 | .001613984 |
| CST2 | 208555_x_at | 0.855 | .00162315 |
| LOC388135 | 230475_at | 0.855 | .001633666 |
| BTN3A2 /// BTN3A3 | 204820_s_at | 0.855 | .001636357 |
| YWHAZ | 200640_at | 0.854 | .00163913 |
| PCDH1 | 203918_at | 0.854 | .00165226 |
| — | 1565921_a_at | 0.854 | .001663428 |
| MPP7 | 1564308_a_at | 0.854 | .001668615 |
| — | 214388_at | 0.854 | .001679183 |
| RIF1 | 214700_x_at | 0.853 | .001687399 |
| — | 243220_at | 0.853 | .001694024 |
| ARMC9 | 219636_s_at | 0.853 | .001699631 |
| PDGFA | 216867_s_at | 0.853 | .001705773 |
| — | 238455_at | 0.853 | .001715305 |
| PHF11 | 221816_s_at | 0.853 | .001719709 |
| RNASE7 | 234699_at | 0.852 | .001728383 |
| LOC221710 | 1564651_at | 0.852 | .001730281 |
| APOH | 231359_at | 0.852 | .001731768 |
| C6orf145 | 212923_s_at | 0.852 | .001735491 |
| RAB27B | 207018_s_at | 0.852 | .001739089 |
| HEMK1 | 218621_at | 0.852 | .001742428 |
| — | 234360_at | 0.852 | .001749024 |
| — | 1560706_at | 0.852 | .00175273 |
| RHOV | 241990_at | 0.852 | .001755418 |
| ACSL1 | 201963_at | 0.851 | .001772222 |
| ATXN10 | 208833_s_at | 0.851 | .001772641 |
| LAMB1 | 211651_s_at | 0.851 | .001777407 |
| FLYWCH1 | 223950_s_at | 0.851 | .001788366 |
| MT1H /// MT1P2 | 206461_x_at | 0.851 | .001795372 |
| DRD3 | 214559_at | 0.851 | .001806848 |
| IGHG1 | 231668_x_at | 0.851 | .001814036 |
| IGHG1 | 216892_at | 0.850 | .00183644 |
| ITGA6 | 201656_at | 0.850 | .001843156 |
| — | 1564545_a_at | 0.850 | .001857061 |
| — | 244299_at | 0.849 | .001869308 |
| — | 227559_at | –0.849 | .001877652 |
| SUFU | 224201_s_at | 0.849 | .001881111 |
| CTNND1 | 208862_s_at | 0.849 | .001887411 |
| OR1J4 | 1567282_at | 0.849 | .001896405 |
| WDSOF1 | 231784_s_at | 0.849 | .001909808 |
| GPR115 | 1553031_at | 0.849 | .001910415 |
| KYNU | 204385_at | 0.849 | .001910833 |
| CD163L1 | 223655_at | 0.848 | .00191887 |
| SLC2A3 | 202498_s_at | 0.847 | .001965926 |
| MKX | 239468_at | 0.847 | .001968037 |
| IL20RA | 222828_at | 0.847 | .001968434 |
| IRF2 | 203275_at | 0.847 | .00196972 |
| LOC283454 | 229552_at | 0.847 | .001987359 |
| OAS1 | 202869_at | 0.846 | .002011152 |
| ACSL1 | 207275_s_at | 0.846 | .002013069 |
| FMO6P | 215174_at | 0.846 | .002047645 |
| UBE2G1 | 209141_at | 0.846 | .002048458 |
| — | 1561665_at | 0.845 | .002062751 |
| — | 1559776_at | 0.845 | .002068145 |
| ARID3A | 205865_at | 0.845 | .002070365 |
| RAB1B | 220964_s_at | 0.845 | .002073368 |
| COMT | 208817_at | 0.845 | .002073531 |
| — | 241824_at | 0.845 | .002083978 |
| SERINC2 | 224762_at | 0.845 | .002084422 |
| MYO1B | 212364_at | 0.845 | .002089921 |
| — | 217402_at | 0.845 | .002090959 |
| KIAA0892 | 217652_at | 0.845 | .002093004 |
| — | 1561546_at | 0.845 | .002101138 |
| C8orf42 | 230903_s_at | 0.845 | .002109804 |
| CLIC3 | 219529_at | 0.844 | .002117141 |
| C10orf47 | 229801_at | 0.844 | .002124408 |
| TAF6L | 213209_at | –0.844 | .002124674 |
| — | 244533_at | 0.844 | .002156908 |
| NRXN3 | 205795_at | 0.844 | .002157418 |
| SWAP70 | 210369_at | 0.844 | .002161039 |
| — | 232580_x_at | –0.843 | .002165243 |
| CMTM7 | 240737_at | 0.843 | .002168088 |
| ARHGDIB | 1555812_a_at | 0.843 | .002182013 |
| ARVCF | 216204_at | 0.843 | .002185495 |
| ZHX1 | 223213_s_at | 0.843 | .002193957 |
| NDE1 | 218414_s_at | 0.842 | .002220596 |
| MT2A | 212185_x_at | 0.842 | .002231013 |
| HRNBP3 | 240975_x_at | 0.842 | .002259245 |
| SLC2A3 | 222088_s_at | 0.842 | .002263084 |
| ZNF395 | 232694_at | 0.841 | .002278503 |
| IL22 | 222974_at | 0.841 | .002282871 |
| CAMSAP1L1 | 217196_s_at | 0.841 | .002297925 |
| KIAA1875 | 233344_x_at | 0.840 | .002330568 |
| GAB4 | 1563816_at | 0.840 | .002335582 |
| BTG1 | 200921_s_at | 0.840 | .002337142 |
| LOC284244 | 214162_at | 0.840 | .0023415 |
| TMEM154 | 238063_at | 0.840 | .002347062 |
| CTNND1 | 208407_s_at | 0.840 | .00234959 |
| LST1 | 210629_x_at | 0.840 | .002351243 |
| — | 1563635_at | 0.840 | .002353984 |
| FBXO21 | 214891_at | 0.840 | .002354999 |
| ARFGEF1 | 202956_at | 0.840 | .002371545 |
| BST2 | 201641_at | 0.840 | .002372959 |
| LOC221710 | 235707_at | 0.839 | .002381449 |
| — | 242888_at | 0.839 | .002387283 |
| GMPPB | 219920_s_at | 0.839 | .002392535 |
| DDX59 | 228386_s_at | 0.839 | .002396877 |
| PRB1 /// PRB2 | 207752_x_at | 0.839 | .002397744 |
| RMND5A | 212479_s_at | 0.839 | .002400299 |
| — | 240138_at | 0.839 | .0024068 |
| SPTLC3 | 227752_at | 0.839 | .002415579 |
| LOC90246 | 233835_at | 0.839 | .002417259 |
| AVIL | 1568706_s_at | 0.839 | .002420725 |
| — | 216401_x_at | 0.839 | .00242863 |
| — | 235952_at | 0.838 | .002440143 |
| SREBF1 | 202308_at | 0.838 | .002450327 |
| CADPS | 234220_at | 0.838 | .002492762 |
| MTMR1 | 214975_s_at | 0.838 | .002492801 |
| ASF1A | 213561_at | –0.837 | .002495471 |
| — | 241964_at | 0.837 | .00250385 |
| PLD1 | 226636_at | 0.837 | .002542909 |
| ZNF238 | 207164_s_at | 0.837 | .002544841 |
| RAC2 | 213603_s_at | 0.836 | .002558114 |
| TRPS1 | 222651_s_at | 0.836 | .002585149 |
| NFKBIL1 | 209973_at | 0.836 | .002600642 |
| DAZAP2 | 235704_at | 0.836 | .002610583 |
| GLDC | 204836_at | 0.835 | .002623627 |
| — | 1556229_at | 0.835 | .002627759 |
| MT1G | 204745_x_at | 0.834 | .002683067 |
| COMMD5 | 223819_x_at | 0.834 | .002684565 |
| ZBED1 | 1554821_a_at | 0.834 | .00269151 |
| FUT9 | 216185_at | 0.834 | .002702537 |
| RASSF6 | 233463_at | 0.833 | .002741102 |
| TMCO1 | 208716_s_at | –0.833 | .00274808 |
| NOTCH3 | 203238_s_at | 0.833 | .002752581 |
| WDR68 | 221745_at | –0.833 | .00275266 |
| SYT8 | 232802_at | 0.833 | .002756566 |
| — | 244421_at | 0.833 | .002784603 |
| MT1X | 208581_x_at | 0.833 | .002793893 |
| TAPBPL | 218746_at | 0.832 | .002843953 |
| GM2A | 209727_at | 0.831 | .002876698 |
| ZFP91 | 224636_at | 0.831 | .002893686 |
| PAK2 | 205962_at | 0.831 | .002895651 |
| HERC4 | 208055_s_at | 0.831 | .002902154 |
| RARB | 208530_s_at | 0.831 | .002909419 |
| MRPL19 | 232071_at | –0.831 | .002922548 |
| KIF1B | 209234_at | –0.830 | .002938703 |
| — | 1563115_at | 0.830 | .002953767 |
| — | 226865_at | 0.830 | .002954056 |
| ARHGDIB | 201288_at | 0.830 | .00295674 |
| DHRS9 | 219799_s_at | 0.830 | .002956858 |
| PTK2 | 241453_at | 0.830 | .002960065 |
| KCNJ10 | 228581_at | 0.830 | .002986919 |
| MMAA | 239852_at | 0.830 | .00299167 |
| PCTK1 | 208824_x_at | 0.829 | .002999509 |
| SLC31A2 | 204204_at | 0.829 | .003018161 |
| — | 213929_at | 0.829 | .003034086 |
| LOC440498 | 232594_at | 0.828 | .003075457 |
| — | 216472_at | 0.828 | .00309135 |
| — | 238608_at | 0.828 | .003092874 |
| SPRR3 | 232082_x_at | 0.828 | .003096419 |
| PPIL6 | 1560910_at | –0.828 | .003123918 |
| RAB25 | 218186_at | 0.827 | .003138768 |
| LOC653390 | 243124_at | 0.827 | .003140286 |
| HFE | 235754_at | 0.827 | .003140489 |
| ZG16 | 214142_at | 0.827 | .003148968 |
| KLK5 | 222242_s_at | 0.827 | .003181985 |
| MPHOSPH6 | 203740_at | 0.827 | .003184455 |
| EEFSEC | 227540_at | –0.827 | .003184589 |
| SAMD9 | 219691_at | 0.827 | .00318901 |
| FLJ11171 | 222811_at | 0.827 | .003190498 |
| — | 243642_x_at | 0.826 | .003200007 |
| — | 238910_at | 0.826 | .003210044 |
| SQSTM1 | 213112_s_at | 0.826 | .003215899 |
| CISH | 223961_s_at | 0.826 | .003219288 |
| 214858_at | 0.826 | .003226501 | |
| HLA-DRB6 | 217362_x_at | 0.826 | .003238648 |
| — | 242496_at | 0.826 | .003242663 |
| SEMA6D | 226492_at | 0.825 | .00327047 |
| IFNG | 210354_at | –0.825 | .003283621 |
| — | 233238_s_at | 0.825 | .003301358 |
| CCL17 | 207900_at | 0.825 | .0033044 |
| FAM119A | 235177_at | 0.825 | .003315215 |
| DUSP11 | 202703_at | 0.825 | .003316907 |
| C17orf64 | 1555985_at | 0.825 | .00331853 |
| CCNA2 | 203418_at | 0.824 | .00333941 |
| SRCAP | 38766_at | 0.824 | .003342189 |
| MAST4 | 243575_at | 0.824 | .003371137 |
| CSF2RA | 207085_x_at | 0.824 | .003380971 |
| FZD10 | 219764_at | 0.824 | .003385397 |
| LOC400258 | 1558421_a_at | 0.824 | .003389472 |
| C1orf74 | 229933_at | 0.824 | .003408177 |
| — | 1570082_x_at | 0.823 | .003413136 |
| TMEM63A | 202699_s_at | 0.823 | .003417679 |
| OR10A5 | 1555651_at | 0.823 | .003423201 |
| STK3 | 211078_s_at | 0.823 | .003441828 |
| PROM2 | 1562378_s_at | 0.823 | .003463437 |
| SNX16 | 219793_at | 0.822 | .003500403 |
| GRTP1 | 229377_at | 0.822 | .003519159 |
| RNF128 | 219263_at | 0.822 | .003533434 |
| KCNAB2 | 203402_at | 0.822 | .003533466 |
| C7orf16 | 220231_at | 0.822 | .00354666 |
| — | 236571_at | 0.822 | .003556566 |
| KLHL6 | 1560397_s_at | 0.821 | .003588152 |
| CASP1 | 211368_s_at | 0.821 | .003592691 |
| COMT | 208818_s_at | 0.821 | .003594844 |
| FOXF2 | 206377_at | 0.821 | .003626729 |
| CAMSAP1L1 | 212763_at | 0.820 | .003635295 |
| BRWD1 | 219280_at | 0.820 | .003657695 |
| EFEMP1 | 201842_s_at | 0.820 | .003658 |
| SOX13 | 38918_at | 0.820 | .003658608 |
| NFKB2 | 209636_at | 0.820 | .003659676 |
| — | 1569578_at | 0.820 | .00366939 |
| — | 1563833_at | 0.820 | .00367425 |
| C2orf3 | 237531_at | 0.820 | .003688268 |
| SMS | 202043_s_at | 0.820 | .0036952 |
| ACE2 | 219962_at | 0.820 | .003704505 |
| MKX | 241902_at | 0.820 | .003704767 |
| URP2 | 223303_at | 0.819 | .003727986 |
| C2orf33 | 222832_s_at | 0.819 | .003744867 |
| AMOTL1 | 228840_at | 0.819 | .003745656 |
| — | 238261_at | –0.819 | .003750427 |
| GAD1 | 206670_s_at | 0.819 | .003755456 |
| ASB4 | 237720_at | 0.818 | .003799135 |
| FLJ32447 | 1553485_at | 0.818 | .003806517 |
| ABCA7 | 219577_s_at | 0.818 | .003807457 |
| — | 224249_at | 0.818 | .003860095 |
| AUP1 | 220525_s_at | 0.817 | .003875864 |
| ERG | 241926_s_at | 0.817 | .003881375 |
| FLJ11506 | 202852_s_at | 0.817 | .003889338 |
| CARD14 | 220598_at | 0.817 | .003898417 |
| ERP27 | 227450_at | 0.817 | .003934642 |
| RICS | 210791_s_at | 0.817 | .003944083 |
| — | 222371_at | 0.816 | .003958272 |
| — | 241445_at | 0.815 | .004061525 |
| FAM13A1 | 217047_s_at | 0.815 | .004063488 |
| — | 207879_at | 0.815 | .004094788 |
| MMP28 | 219909_at | 0.815 | .004105559 |
| SAMD9L | 226603_at | 0.815 | .004106379 |
| — | 244236_at | 0.814 | .004114938 |
| LOC727869 /// LOC730704 | 239241_at | 0.814 | .004134163 |
| MYOM2 | 205826_at | 0.814 | .004137715 |
| TAPT1 | 242318_at | 0.814 | .004141651 |
| C8orf38 | 230016_at | 0.814 | .004143303 |
| — | 224999_at | 0.814 | .004151581 |
| ZNF706 | 227132_at | 0.814 | .004154386 |
| IKBKB | 209341_s_at | 0.814 | .004159844 |
| HNRPA3P1 | 206808_at | 0.814 | .004162142 |
| PXMP4 | 224210_s_at | 0.814 | .004167983 |
| GATAD2A | 236932_s_at | 0.813 | .004203776 |
| FNTA | 209471_s_at | 0.813 | .004236758 |
| ARHGEF10 | 1554703_at | 0.813 | .004255433 |
| — | 238059_at | 0.813 | .004269389 |
| PIAS1 | 217863_at | 0.812 | .004288345 |
| EEA1 | 204840_s_at | 0.812 | .004291171 |
| FLJ25801 | 1552580_at | 0.812 | .004311859 |
| SPECC1 | 223498_at | 0.812 | .004317165 |
| — | 1556942_at | 0.812 | .004339552 |
| ISYNA1 | 228417_at | 0.811 | .004386638 |
| GYPA | 205838_at | 0.811 | .004396409 |
| LOC652526 /// LOC727927 /// PDE4DIP | 212392_s_at | 0.811 | .004405774 |
| CAPN1 | 200752_s_at | 0.811 | .004419665 |
| LOC442142 | 240325_x_at | 0.811 | .004429915 |
| EPB41L4B | 220161_s_at | 0.811 | .004442948 |
| TKT | 208700_s_at | 0.810 | .00446237 |
| LOC56755 | 239802_at | 0.810 | .004468293 |
| TMEM65 | 238045_at | 0.810 | .004495792 |
| HADHA | 208631_s_at | 0.810 | .004533718 |
| WWP1 | 212637_s_at | 0.809 | .004558126 |
| C1orf170 | 224501_at | 0.809 | .004569907 |
| — | 244154_at | –0.809 | .004586537 |
| NAV3 | 204823_at | 0.809 | .004612525 |
| C6orf105 | 229070_at | 0.809 | .004615649 |
| ILK | 235906_at | –0.809 | .004623782 |
| IFIT3 | 204747_at | 0.809 | .004635508 |
| LOC283508 | 227415_at | 0.808 | .004649986 |
| C10orf118 | 219844_at | 0.808 | .004678258 |
| ZNF331 | 219228_at | 0.808 | .004688435 |
| OXR1 | 238409_x_at | 0.808 | .004717622 |
| EIF3S3 | 201592_at | 0.807 | .004742921 |
| METTL4 | 219698_s_at | 0.807 | .004757206 |
| INTS6 | 218819_at | 0.807 | .004766066 |
| — | 236180_at | 0.807 | .004785638 |
| ARHGDIB | 1555811_at | 0.807 | .004801594 |
| CASP7 | 207181_s_at | 0.806 | .004831391 |
| TTBK1 | 240643_at | 0.806 | .004833173 |
| S100B | 209686_at | 0.806 | .004852485 |
| IL24 | 206569_at | 0.806 | .004857251 |
| RIN2 | 209684_at | 0.806 | .004885855 |
| TRIM16 /// TRIM16L | 204341_at | 0.805 | .004927125 |
| DOCK8 | 232843_s_at | 0.805 | .00494154 |
| MTMR1 | 216095_x_at | 0.805 | .004944024 |
| MICALL1 | 55081_at | 0.805 | .004992872 |
| MARK1 | 1560407_at | 0.805 | .005004958 |
| EML3 | 212969_x_at | 0.805 | .005010214 |
| CCNA2 | 213226_at | 0.804 | .005017077 |
| TRAF3IP3 | 231932_at | 0.804 | .005018958 |
| KIF14 | 206364_at | 0.804 | .005029019 |
| ITPK1 | 217710_x_at | 0.804 | .005053834 |
| PXMP4 | 219428_s_at | 0.804 | .005063347 |
| EGFR | 211607_x_at | 0.804 | .005085003 |
| MTHFSD | 222769_at | 0.804 | .005091792 |
| — | 238671_at | 0.804 | .005093148 |
| — | 244851_at | 0.803 | .005115363 |
| TBC1D8B | 219771_at | 0.803 | .005116375 |
| ZCCHC6 | 242776_at | 0.803 | .005185463 |
| TKT | 208699_x_at | 0.803 | .005186386 |
| — | 240529_at | 0.803 | .005202653 |
| SLC2A3 | 202499_s_at | 0.803 | .005204794 |
| ST3GAL3 | 231659_at | 0.802 | .005273228 |
| LGI1 | 206349_at | 0.802 | .005274536 |
| LHFP | 218656_s_at | 0.802 | .005276132 |
| PWWP2 | 227999_at | 0.802 | .005276218 |
| MUPCDH | 219796_s_at | 0.802 | .005301213 |
| HNRPM | 233605_x_at | –0.801 | .005312163 |
| PTAFR | 206278_at | 0.801 | .005325715 |
| SUGT1 | 223330_s_at | 0.801 | .005335855 |
| C17orf69 | 1553399_a_at | 0.801 | .005336322 |
| IVL | 214599_at | 0.801 | .005349155 |
| TRIP10 | 202734_at | 0.801 | .00536423 |
| — | 239546_at | 0.801 | .005371975 |
| — | 243159_x_at | 0.800 | .005412221 |
| C8orf38 | 235509_at | 0.800 | .005416723 |
| AFTPH | 217939_s_at | 0.800 | .005421917 |
| RNF141 | 219104_at | 0.800 | .005439594 |
| GM2A | 235678_at | 0.800 | .005485109 |
| CCDC132 | 207045_at | 0.800 | .005493997 |
| AMN | 1563792_at | 0.800 | .005503057 |
| KIAA1602 | 231865_at | –0.799 | .005511781 |
| CAMK2G | 212757_s_at | 0.799 | .005530217 |
| IFI35 | 209417_s_at | 0.799 | .005541108 |
| TRIOBP | 202795_x_at | 0.799 | .005548676 |
| — | 240872_at | 0.799 | .005549347 |
| — | 1569898_a_at | 0.799 | .005553831 |
| GRIN2D | 207036_x_at | 0.799 | .005577057 |
| ERCC4 | 210158_at | –0.799 | .005579169 |
| RRAGA | 201628_s_at | –0.799 | .005584498 |
| CXCL16 | 223454_at | 0.799 | .005605795 |
| — | 236962_at | 0.798 | .00561684 |
| — | 226187_at | 0.798 | .005621204 |
| USP45 | 224441_s_at | –0.798 | .00562458 |
| MARVELD3 | 239350_at | 0.798 | .00563971 |
| TMEM65 | 241342_at | 0.798 | .005665423 |
| NFKB1 | 209239_at | 0.798 | .005670009 |
| — | 1560775_at | 0.798 | .005710928 |
| TCF7L1 | 221016_s_at | 0.797 | .005723249 |
| CD38 | 205692_s_at | 0.797 | .005730065 |
| CD40 | 35150_at | 0.797 | .005735148 |
| LOC727893 /// PDE4DIP | 212390_at | 0.797 | .005738131 |
| CREBL2 | 201990_s_at | –0.797 | .005750415 |
| DPP6 | 1554796_at | 0.797 | .005751264 |
| CXorf18 | 1564491_at | 0.797 | .005764147 |
| NRXN3 | 215021_s_at | 0.797 | .005775305 |
| JAKMIP2 | 205889_s_at | 0.796 | .005854345 |
| GEMIN8 | 222854_s_at | 0.796 | .005866105 |
| NAV3 | 1552658_a_at | 0.796 | .005881443 |
| — | 228910_at | 0.796 | .005912611 |
| RAP2B | 238622_at | 0.796 | .005916464 |
| SMAD1 | 210993_s_at | 0.796 | .005927736 |
| DCT | 205338_s_at | 0.795 | .005929617 |
| PSME2 | 201762_s_at | 0.795 | .005944051 |
| ZNF100 | 1569637_at | –0.795 | .005950837 |
| PLD1 | 177_at | 0.795 | .005957137 |
| — | 240076_at | 0.795 | .006003698 |
| TCAP | 205766_at | 0.794 | .006046255 |
| 240059_at | 0.794 | .00606078 | |
| SYNGR3 | 205691_at | 0.794 | .006078721 |
| — | 225896_at | 0.794 | .006079495 |
| C4orf21 | 231204_at | 0.794 | .00607978 |
| FAM78A | 227002_at | 0.794 | .006084997 |
| ADK | 204120_s_at | 0.794 | .006094341 |
| ARMC1 | 218185_s_at | 0.794 | .006118243 |
| MDGA1 | 232237_at | 0.793 | .006174679 |
| VPS37B | 221704_s_at | 0.793 | .006222846 |
| CTNND1 | 211240_x_at | 0.793 | .006224248 |
| — | 241454_at | 0.793 | .006235244 |
| NT5C1B | 243100_at | 0.792 | .006260471 |
| — | 216421_at | 0.792 | .006263971 |
| — | 228951_at | 0.792 | .006276046 |
| C17orf66 | 1553378_a_at | 0.792 | .006280574 |
| C2orf33 | 219137_s_at | 0.792 | .006289352 |
| REV3L | 238736_at | –0.792 | .006294689 |
| WDR22 | 224697_at | –0.792 | .00633677 |
| — | 238201_at | –0.792 | .006361852 |
| TRPV6 | 206827_s_at | 0.792 | .006368952 |
| AFM | 206840_at | 0.791 | .006397914 |
| — | 243328_at | 0.791 | .006426838 |
| CAMSAP1L1 | 212765_at | 0.791 | .006464974 |
| CHD3 | 208807_s_at | 0.791 | .006465844 |
| — | 1556753_s_at | 0.791 | .006471437 |
| CA5B | 214082_at | 0.790 | .006504198 |
| RAD23B | 201223_s_at | 0.790 | .006523727 |
| ZNF469 | 230440_at | 0.790 | .006525491 |
| — | 244045_at | 0.790 | .006555826 |
| LOC401320 | 233732_at | 0.790 | .006559155 |
| B4GALNT4 | 238080_at | 0.790 | .006575281 |
| FNTA | 200090_at | 0.790 | .006576471 |
| CD164 | 208405_s_at | –0.790 | .006580873 |
| TPST2 | 204079_at | 0.790 | .006590405 |
| MTERFD1 | 219363_s_at | 0.789 | .006635776 |
| — | 217372_at | 0.789 | .006648665 |
| MYEF2 | 229464_at | –0.789 | .006695533 |
| PTPRN2 | 203029_s_at | 0.789 | .00670284 |
| M-RIP | 214771_x_at | 0.789 | .006703526 |
| GATA6 | 210002_at | 0.789 | .006707294 |
| NDUFA10 | 1554719_at | –0.789 | .006710476 |
| MT1P2 | 211456_x_at | 0.789 | .006721614 |
| SSH3 | 219919_s_at | 0.788 | .006722508 |
| DDX42 | 1559953_at | 0.788 | .006727047 |
| TAF6L | 230049_at | 0.788 | .006753029 |
| CHN2 | 213385_at | 0.788 | .006762142 |
| KRT40 | 1562629_a_at | 0.788 | .00676946 |
| TULP1 | 206705_at | 0.788 | .006778479 |
| LTBR | 243400_x_at | 0.788 | .006784405 |
| RHOBTB3 | 225202_at | 0.788 | .006785471 |
| — | 1563822_at | 0.788 | .00681172 |
| CENPA | 204962_s_at | 0.788 | .006813064 |
| SLC5A10 | 239707_at | 0.788 | .006820087 |
| NUCKS1 | 222424_s_at | 0.787 | .006849448 |
| BICD2 | 212702_s_at | –0.787 | .006865855 |
| FCER1A | 211734_s_at | –0.787 | .006868829 |
| DDX59 | 228385_at | 0.787 | .006902606 |
| MMRN2 | 236262_at | 0.787 | .006911925 |
| MGC9712 | 235817_at | 0.787 | .006927719 |
| PROM2 | 239528_at | 0.787 | .006945973 |
| PLAC9 | 227419_x_at | 0.787 | .006950863 |
| PRDX5 | 1560587_s_at | 0.786 | .006965344 |
| — | 227092_at | 0.786 | .006966347 |
| SLC45A2 | 220245_at | 0.786 | .006967479 |
| CASP4 | 209310_s_at | 0.786 | .007058382 |
| CCNC | 201955_at | –0.785 | .007087437 |
| JUP | 201015_s_at | 0.785 | .007108058 |
| CAMK2G | 212669_at | 0.785 | .007114348 |
| HOXC13 | 219832_s_at | 0.785 | .007150384 |
| HAL | 206643_at | –0.785 | .007161649 |
| ZNF335 | 221890_at | 0.785 | .007165635 |
| MTMR3 | 202197_at | 0.785 | .00716983 |
| — | 243494_at | 0.785 | .007173611 |
| RGS12 | 214361_s_at | 0.784 | .007237184 |
| IER5 | 218611_at | 0.784 | .007254477 |
| LTBP4 | 227989_at | 0.784 | .007278941 |
| TAL2 | 231759_at | 0.784 | .007282788 |
| — | 238233_at | 0.784 | .007299283 |
| LY9 | 215967_s_at | 0.784 | .007307315 |
| FAM13A1 | 202973_x_at | 0.783 | .007346237 |
| FLJ20581 | 220061_at | 0.783 | .007347289 |
| — | 226002_at | 0.783 | .007363657 |
| TCF21 | 204931_at | 0.783 | .007367266 |
| Kua /// Kua-UEV /// LOC730052 /// LOC732137 /// RNPEP /// UBE2V1 | 201003_x_at | 0.783 | .007381836 |
| SLC29A3 | 219344_at | 0.783 | .007387299 |
| C3orf41 | 228721_at | 0.783 | .007389528 |
| NPC1L1 | 224306_at | 0.783 | .007398687 |
| LOC90925 | 210450_at | 0.783 | .007406019 |
| HADH | 201035_s_at | 0.783 | .007421586 |
| PRDM6 | 230311_s_at | 0.782 | .007466048 |
| CDC42BPG | 1569044_at | 0.782 | .007481495 |
| — | 1557599_a_at | 0.782 | .007496622 |
| CAB39L | 225914_s_at | 0.782 | .007500117 |
| — | 236440_at | 0.782 | .007502711 |
| RNF24 | 204669_s_at | 0.782 | .007509366 |
| SH2D1A | 210116_at | 0.782 | .007514443 |
| CSNK1A1 | 213086_s_at | 0.782 | .007522973 |
| HERC4 | 225988_at | 0.782 | .007552986 |
| C8orf42 | 226778_at | 0.782 | .007573915 |
| C13orf18 | 44790_s_at | 0.782 | .007576146 |
| SPRR1A | 214549_x_at | 0.782 | .007586237 |
| — | 222260_at | 0.781 | .007591809 |
| EXPH5 | 214734_at | 0.781 | .007609064 |
| PAIP2 | 222983_s_at | –0.781 | .007630822 |
| MCTP2 | 220603_s_at | 0.781 | .007633993 |
| FLCN | 1552664_at | 0.781 | .007657708 |
| ATR | 209903_s_at | 0.781 | .007674296 |
| RELA | 230202_at | 0.780 | .00772333 |
| — | 240142_at | 0.780 | .007740633 |
| OXR1 | 222553_x_at | 0.780 | .007744367 |
| BHLHB2 | 201169_s_at | 0.780 | .007762154 |
| MAP3K13 | 1562440_at | 0.780 | .007785454 |
| TMSB10 | 217733_s_at | –0.780 | .007788609 |
| TGM6 | 233983_at | 0.780 | .007790516 |
| KIAA1604 | 226588_at | 0.780 | .007792747 |
| DNM1DN8-2 | 1561249_a_at | 0.780 | .007815858 |
| SLC35D1 | 209711_at | 0.779 | .007849198 |
| RAC2 | 207419_s_at | 0.779 | .007856687 |
| MYEF2 | 222772_at | –0.779 | .007863126 |
| CDKL1 | 207766_at | 0.779 | .007898575 |
| KRT5 | 201820_at | 0.779 | .007934021 |
| SSX2IP | 203019_x_at | 0.779 | .007941753 |
| PAX6 | 205646_s_at | 0.779 | .007944583 |
| SLC4A7 | 210286_s_at | 0.779 | .007971765 |
| ZNF396 | 1570030_at | 0.778 | .008011268 |
| EML5 | 1570393_at | 0.778 | .008026755 |
| — | 1566487_at | 0.778 | .008033756 |
| IMPAD1 | 222654_at | 0.778 | .008065384 |
| DAPP1 | 222858_s_at | 0.778 | .008085896 |
| CREBL2 | 201989_s_at | –0.778 | .008094564 |
| PRR4 | 204919_at | –0.777 | .008123782 |
| — | 232198_at | –0.777 | .008134346 |
| — | 1566994_at | 0.777 | .0081721 |
| FUT6 | 210399_x_at | 0.777 | .008204959 |
| TRIM29 | 202504_at | 0.777 | .008209 |
| — | 1562260_at | 0.776 | .008262687 |
| — | 1557521_a_at | 0.776 | .008280327 |
| DGKH | 1553300_a_at | 0.776 | .008311519 |
| PSG3 | 203399_x_at | 0.776 | .008343066 |
| HDAC2 | 201833_at | –0.776 | .008362896 |
| SLK | 206875_s_at | 0.776 | .008372311 |
| PCDH8 | 206935_at | 0.776 | .008384849 |
| IKBKB | 209342_s_at | 0.775 | .008394042 |
| — | 241431_at | 0.775 | .008401163 |
| RDX | 212398_at | 0.775 | .008411054 |
| VWA1 | 225983_s_at | 0.775 | .008417863 |
| — | 244889_at | 0.775 | .008445237 |
| B3GNTL1 | 215055_at | 0.775 | .008468302 |
| KRIT1 | 216713_at | 0.775 | .008514058 |
| C9orf85 | 238579_at | 0.774 | .008550295 |
| — | 244393_x_at | 0.774 | .008560579 |
| IL1RN | 212659_s_at | –0.774 | .008571989 |
| — | 1564389_at | 0.774 | .008574094 |
| CCNE2 | 205034_at | 0.774 | .008579356 |
| FKSG83 | 224289_s_at | 0.774 | .008582851 |
| JDP2 | 226267_at | 0.774 | .008587395 |
| NUDT6 | 220183_s_at | 0.774 | .008590425 |
| — | 1561103_at | 0.774 | .008595799 |
| ZDHHC13 | 219296_at | 0.774 | .008612982 |
| PPP2R2C | 228025_s_at | 0.774 | .008615137 |
| — | 1565617_at | 0.774 | .00861515 |
| PPBPL2 | 208346_at | 0.774 | .008640884 |
| LOC116236 | 226796_at | 0.774 | .008664417 |
| MMRN2 | 219091_s_at | 0.774 | .008666795 |
| GJB2 | 223278_at | 0.773 | .008672809 |
| SCIN | 222272_x_at | 0.773 | .008674919 |
| SCD5 | 220232_at | 0.773 | .008679686 |
| — | 242035_at | –0.773 | .008710971 |
| — | 243730_at | 0.773 | .008716576 |
| MOBK1B | 201297_s_at | 0.773 | .008740967 |
| COL4A3 | 216367_at | 0.773 | .008773554 |
| LOC51252 | 223812_at | 0.772 | .008817172 |
| TIFA | 226117_at | 0.772 | .008828231 |
| RAD21 | 200607_s_at | 0.772 | .00884052 |
| ZFP36L2 | 201367_s_at | 0.772 | .008840894 |
| FLJ33590 | 1560035_at | 0.772 | .008866062 |
| MTHFSD | 1554495_s_at | –0.772 | .008878666 |
| — | 1561912_at | 0.771 | .008982852 |
| CSNK1A1 | 1556006_s_at | 0.771 | .009003047 |
| GLYATL2 | 1554712_a_at | 0.771 | .009006409 |
| CA5B | 207129_at | 0.771 | .009032829 |
| GABRE | 204537_s_at | 0.771 | .009042537 |
| PCMTD1 | 226119_at | 0.771 | .009063088 |
| RAB27B | 207017_at | 0.770 | .00911161 |
| RGS1 | 216834_at | 0.770 | .009118744 |
| — | 228120_at | –0.770 | .009127662 |
| LHX9 | 1565407_at | 0.770 | .009148302 |
| EXOSC7 | 213648_at | –0.770 | .009152021 |
| C1orf174 | 238010_at | 0.770 | .009155857 |
| — | 232413_at | 0.770 | .009215494 |
| CCDC9 | 206257_at | 0.770 | .009229145 |
| PRDM16 | 220928_s_at | 0.769 | .009265498 |
| TJP3 | 213412_at | 0.769 | .009266725 |
| DAOA | 1555662_s_at | 0.769 | .009338148 |
| SLC25A37 | 221920_s_at | 0.769 | .009347573 |
| IL16 | 1555016_at | –0.769 | .009362772 |
| CAPZA1 | 208374_s_at | 0.769 | .009368262 |
| UTP14A | 221098_x_at | –0.768 | .009401998 |
| GCNT2 | 211020_at | 0.768 | .009403367 |
| PTGER4 | 204896_s_at | 0.768 | .009407667 |
| MAPK3 | 212046_x_at | 0.768 | .009417769 |
| GPR37 | 214586_at | 0.768 | .009424663 |
| ENOSF1 | 213645_at | –0.768 | .009438197 |
| MYLIP | 223129_x_at | 0.768 | .009443719 |
| MT1X | 204326_x_at | 0.768 | .009447529 |
| — | 233900_at | 0.768 | .009449878 |
| TNFRSF21 | 214581_x_at | 0.768 | .009506355 |
| KIR2DS2 | 211532_x_at | 0.768 | .00951985 |
| TPM3 | 222976_s_at | –0.768 | .009521457 |
| KHDRBS2 | 215527_at | –0.767 | .00957987 |
| IL1F7 | 221470_s_at | 0.767 | .009586593 |
| TNRC18 | 1558238_at | 0.767 | .009592464 |
| TMED7 | 209404_s_at | 0.767 | .009613045 |
| — | 1569127_at | 0.767 | .009624543 |
| — | 225159_s_at | 0.767 | .00964604 |
| — | 242495_at | 0.767 | .009651069 |
| — | 234328_at | 0.767 | .009655258 |
| — | 236830_at | –0.767 | .009686237 |
| FUT6 | 211885_x_at | 0.766 | .00970477 |
| LGALS3 | 208949_s_at | 0.766 | .00971114 |
| TRIM34 /// TRIM6-TRIM34 | 224175_s_at | 0.766 | .00972372 |
| LOC130576 | 228360_at | 0.766 | .009741608 |
| MUC3B | 214898_x_at | 0.766 | .009742131 |
| SCAMPER | 1555722_at | 0.766 | .009752813 |
| GRHL2 | 219388_at | 0.766 | .009756076 |
| LZTR2 | 1555289_at | 0.766 | .009763046 |
| MAP7D2 | 228262_at | 0.766 | .009774944 |
| DKFZP564J0863 | 223452_s_at | 0.766 | .009803515 |
| TRIOBP | 210276_s_at | 0.766 | .00980739 |
| LGI4 | 227821_at | 0.765 | .00987066 |
| NXPH1 | 232377_at | 0.765 | .009881309 |
| PLK4 | 211088_s_at | 0.765 | .009887287 |
| ESRRB | 207726_at | 0.765 | .009913306 |
| — | 231098_at | 0.765 | .009978027 |
| — | 1557026_at | 0.765 | .009995907 |
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