From Bench to Bedside: T1 Translation of Basic Behavioral Science into Novel Pediatric Obesity Interventions









Sylvie Naar, PhD, Editor
As 40% of premature deaths can be attributed to preventable behavioral factors, the single greatest opportunity to improve health lies in changing personal behavior such as diet and physical activity. Yet, one out of every three US children is overweight or obese, and obesity rates have not declined among minority youth. There are many reasons for this lack of progress in incorporating successful healthy lifestyle treatments into pediatric care and community settings, and one critical concern involves the limited “pool” of efficacious behavioral treatments available. There are limited efficacious pediatric obesity interventions available for clinical and community settings, and successful weight loss trials for minority youth are rare. Even fewer interventions have been shown to significantly improve clinical health outcomes such as adiposity, glucose intolerance, blood pressure, and cholesterol level, and maintenance of behavior change over the long term remains a challenge.


According to the Institute of Medicine, the first stage of translational research (T1) focuses on “the transfer of new understandings of disease mechanisms gained in the laboratory into the development of new methods for diagnosis, therapy, and prevention and their first testing in humans.” T1 research in which “bench” findings are applied to the “bedside” is less common in the behavioral arena. Thus, advances in our understanding of fundamental human processes, such as motivation, emotion, cognition, self-regulation, communication, stress, and social networks, are not being optimally applied to our most pressing behavioral health problems. This issue focuses on promising behavioral treatments for pediatric obesity “in the pipeline” that have been translated from basic behavioral science and are the process of refinement and proof of concept testing. In this issue, Czajkowski and colleagues describe the ORBIT model for behavioral intervention development, and the first eight articles in this issue describe studies that address designing and preliminary testing of new interventions per the ORBIT model. The last article (Resnicow and colleagues) describes new directions in the implementation of an evidence-based practice in primary care settings. We thank the authors for their commitment to the dissemination of promising strategies to curb the obesity epidemic.


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Oct 2, 2017 | Posted by in PEDIATRICS | Comments Off on From Bench to Bedside: T1 Translation of Basic Behavioral Science into Novel Pediatric Obesity Interventions

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