First Trimester Pelvic Pain
Roya Sohaey, MD
DIFFERENTIAL DIAGNOSIS
Common
Hemorrhagic Cyst
Corpus Luteum Cyst
Ectopic Pregnancy
Less Common
Adnexal Torsion
Appendicitis
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
First rule out ectopic pregnancy (EP)
Is there an intrauterine pregnancy (IUP)?
Presence of IUP best evidence against EP
Heterotopic ectopics are rare
Is the human chorionic gonadotropin (hCG) level high enough to see an IUP?
Should see IUP if hCG levels are > 2000 mIU/mL IRP (international reference preparation)
Lack of IUP at low hCG levels does not rule out EP
EP are not normal pregnancies and may have lower hCG levels
Look for blood in cul-de-sac
Look for an adnexal mass
EP itself or a hematoma
Look for EP on same side as the corpus luteum
Evaluate ovary on side of pain
Is the ovary enlarged?
Consider torsion
Is there a mass or mass-like lesion?
Characterize mass wall
Evaluate internal morphology
Doppler ultrasound
Variable findings with torsion
Compare with other ovary
Peripheral flow in EP (“ring of fire”) and ovarian cysts
Internal flow in neoplasm
Rule out other causes for pain
Gastrointestinal
Compression ultrasound for appendicitis
Inflamed bowel
Genitourinary
Hydronephrosis
Ureteral calculi
Pyelonephritis
Helpful Clues for Common Diagnoses
Hemorrhagic Cyst
Usually from hemorrhage into a corpus luteum
Acute and subacute findings
Reticular lace-like pattern
Fibrin strands not true septations
Retracting blood clot
Findings on follow-up
Fluid-fluid level
Anechoic cyst
Mass should resolve completely with time
6 week follow-up recommended
Role of Doppler
No internal flow
Rule out associated torsion
Corpus Luteum Cyst
Abbreviated CL
Variable wall appearance
Thick, hyperechoic wall most common
Thin wall if large cyst
Variable internal echoes
Anechoic
Complex if hemorrhagic
Solid appearing if thick wall and no fluid
Doppler findings
Low resistive vascular flow in cyst wall
No internal flow
Rule out associated torsion
Ectopic Pregnancy
Uterine findings
Thin or thick endometrial cavity
“Pseudogestational sac” from blood in endometrial cavity
Endometrial cysts can mimic early IUP
Rare heterotopic pregnancy (IUP + EP)
Variable adnexal findings with tubal EP
Tubal distention or hematoma
Tubal gestational sac separate from ovary
EP on same side as CL in 85%
Doppler findings
Low resistive, high velocity flow
“Ring of fire”
Peritoneal blood
Echogenic fluid in cul-de-sac
Look higher up for abdominal blood
Unusual EP locations
Interstitial/cornual
Cervical
Ovarian
Abdominal
Helpful Clues for Less Common Diagnoses
Adnexal Torsion
Usually involves both ovary and tube
Ovary is almost always enlarged
Right > left (3:2)
Peripheral cysts from central edema
Fluid-debris levels in cysts seen with high resolution scanning
Doppler findings
Venous flow lost first
Variable arterial findings secondary to dual blood supply to ovaries
Associated adnexal mass common
Dermoid
Corpus luteum
Tubal cyst
Serous cystadenoma
Free fluid in cul-de-sac
Mostly anechoic
Appendicitis
Appendix may be in an atypical position
Gravid uterus lifts appendix out of pelvis
Have patient point to focal area of tenderness
Graded compression ultrasound with high resolution linear probe
Blind-ending tubular structure
> 6 mm outer to outer wall diameter
Periappendiceal fluid
Echogenic fat surrounds inflamed appendix
Inflammatory mass if rupturedStay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree