Fetal Growth and Well-Being
18.1 Fetal Biometry and Growth
Description and Clinical Features
Fetal measurements play an important role in second and third trimester ultrasound. Two of the key uses of measurements are assessment of gestational age and estimation of fetal weight.
Sonographic assessment of gestational age becomes progressively less accurate as pregnancy progresses because of increasing biologic variability in fetal size. Thus, fetal measurements should be used to determine gestational age only at the initial sonogram during the pregnancy. At subsequent scans, the best estimate of gestational age is the age determined at the initial scan plus the number of intervening weeks.
Fetal weight estimation is generally reserved for scans done during the third trimester. Once the weight has been estimated, it is then compared to norms for gestational age in order to determine whether the fetus is appropriate in size (generally taken to be a weight between the 10th and 90th percentiles), small, or large for gestational age. Small fetal size may indicate growth restriction due to placental, chromosomal, or infectious causes and should prompt further assessment. Large fetal size may affect decisions regarding route of delivery.
The fetal body parts whose measurements are generally used for these purposes in the second and third trimesters are the head, abdomen, and femur. The method for measuring these structures is presented below. While measurements of other fetal parts are used for several diagnostic purposes, including diagnosis of urinary tract dilation, cerebral ventriculomegaly, skeletal dysplasias, and aneuploidy, these applications of fetal biometry are covered in other sections of this book and are not discussed here.
Sonography
Measurements of the fetal head (Figure 18.1.1) are obtained on an image in the axial plane that includes the thalami and cavum septum pellucidum, with the falx in the midline. The head should lie horizontally on the image, with its long axis at or close to 90 degrees to the ultrasound beam. The measurements that can be obtained from this image include:
Biparietal diameter (BPD): Measurement of the width of the head from the outer edge of the skull closest to the transducer to the inner edge of the distal skull (leading edge to leading edge).
Occipitofrontal diameter (OFD): Measurement of the length of the head from the middle of the anterior skull to the middle of the posterior skull.
Head circumference (HC): Measurement of the outer perimeter of the skull.
Measurements of the fetal abdomen (Figure 18.1.2) are obtained on a transverse plane through the upper abdomen that includes the stomach and a portion of the intrahepatic umbilical vein, ideally at its junction with the left portal vein. The abdomen should be round, with its width equal or close to the anterior-to-posterior diameter. The measurements that can be obtained on this image include:
Anteroposterior diameter: Measurement from the anterior skin surface to the skin surface behind the fetal spine.
Transverse diameter: Measurement from one lateral skin surface to the opposite skin surface, in a direction perpendicular to the anteroposterior diameter.
Abdominal circumference: Measurement of the periphery of the abdomen around the outer edge of the skin surface.
Measurement of the fetal femur (Figure 18.1.3) is performed on an image in which the bone lies horizontally, with the ends of the ossified portion (representing the diaphysis) clearly seen. The femur length is measured with calipers placed at the ends of the diaphysis. It is important not to include the cartilaginous epiphysis at the proximal femur or the cartilaginous condyles at the distal femur, whose surfaces may be seen as a linear projection from the diaphysis.
Figure 18.1.2 Fetal abdominal measurements. A: Transverse image of the fetal abdomen at 28 weeks gestation at the correct level and plane for obtaining measurements. The junction of the umbilical vein (long arrow) and left portal vein (short arrow) is seen, as is the stomach (*). B: Anteroposterior diameter (calipers 1) is measured from the anterior skin surface to the posterior skin surface. Transverse diameter (calipers 2) is measured from one lateral skin surface to the opposite skin surface. C: Abdominal circumference (elliptical calipers) is measured around the outer perimeter of the abdomen.
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