Chapter 329 Eosinophilic Gastroenteritis
Eosinophilic gastroenteritis consists of a group of rare and poorly understood disorders that have in common gastric and small intestine infiltration with eosinophils and peripheral eosinophilia. The esophagus and large intestine may also be involved. Tissue eosinophilic infiltration can be seen in mucosa, muscularis, or serosa. Mucosal involvement can produce nausea, vomiting, diarrhea, abdominal pain, gastrointestinal bleeding, protein-losing enteropathy, or malabsorption. Involvement of the muscularis can produce obstruction (especially of the pylorus), whereas serosal activity produces eosinophilic ascites.
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