Discussion: ‘Predicting spontaneous preterm birth’ by Esplin et al

In the roundtable that follows, clinicians discuss a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research. Article discussed:

Esplin MS, Merrell K, Goldenberg R, et al; the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units. Proteomic identification of serum peptides predicting subsequent spontaneous preterm birth. Am J Obstet Gynecol 2011;204:391.e1-8.

Discussion questions

  • Was the overall study design a good choice?

  • What was the Preterm Prediction Study?

  • Was it reasonable to use data from the early 1990s?

  • What were the main findings?

  • What does ITIH4 do?

  • What were the study’s strengths and weaknesses?

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May 31, 2017 | Posted by in GYNECOLOGY | Comments Off on Discussion: ‘Predicting spontaneous preterm birth’ by Esplin et al

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