The article below summarizes a roundtable discussion of a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research. Article discussed:
Berrébi A, Assouline C, Bessières M-H, et al. Long-term outcome of children with congenital toxoplasmosis. Am J Obstet Gynecol 2010;203:552.e1-6.
The full discussion appears at www.AJOG.org , pages e1-3.
Discussion Questions
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What was the study design?
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Why is France a good study site?
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What were the key findings?
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What does this study mean to us?
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What are the study’s strengths and weaknesses?
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How might future research be conducted?
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Should we implement prenatal toxoplasmosis screening?
Congenital toxoplasmosis is rare in the United States, but other countries with a higher incidence have adopted universal prenatal screening for infection. In France, where consumption of raw meat likely boosts the number of cases, pregnant women have long undergone routine periodic testing. Therefore, the country is an ideal site for the study of long-term outcomes among those infected in utero. This month, Journal Club members discussed a study by Berrébi and colleagues, who accumulated data on congenital disease over a 20-year period.
See related article, page 552
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