Learning Objectives
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Identify the contents and indications for various blood component therapies.
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Recognize and manage transfusion reactions.
In the event of a hemorrhage, blood transfusion can be lifesaving. The obstetric team must be well-versed in when to transfuse which products as well as how to respond to transfusion reactions ( Fig. 18.1 ).
Blood Components
Tables 18.1 shows the components of blood products and the expected clinical response to each product.
Table 18.1
Blood Product | Contents | Volume | Expected Effect |
---|---|---|---|
Packed red blood cells (RBCs) | Red blood cells | 250–350 mL | Raise hemoglobin by 1 g/dL |
Platelets (given as “superpack” of 6 units) | Platelets | 250–300 mL | Raise platelets by 30,000/mm 3 |
Fresh frozen plasma (FFP) | All clotting factors | 200–300 mL | Raise fibrinogen by 8–10 mg/dL |
Cryoprecipitate (given as pool of five bags) | Fibrinogen, vWF, factor VIII, factor XIII | 100 mL | Raise fibrinogen by 50 mg/dL |
Time | Comments | ||
---|---|---|---|
Initial response | Recognized transfusion reaction | ||
Stopped blood transfusion | |||
Notified physician | |||
Airway | Checked for airway compromise, anaphylaxis | ||
Breathing | Checked breathing | ||
Circulation | Maintained patency of IV with normal saline | ||
Took blood pressure | |||
Interventions | Checked urine for hematuria | ||
Sent sample of patient’s blood to blood bank | |||
Bolused normal saline | |||
Documentation | Timing of events | ||
Notification of blood bank | |||
Persons present | |||
Communication | Directed communication | ||
Closed-loop communication |