Blood banking/immunohematology is an area of laboratory medicine that involves the preparation of blood and blood components for transfusion as well as the selection and monitoring of those components following transfusion. The preparation, modification, and indications of both traditional and newer products are described in this review, along with special considerations for neonates, patients undergoing hematopoietic stem cell transplantation, those with sickle cell disease, and others. Immunohematological techniques are critical in the provision of blood and blood products and are briefly discussed.
Key points
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Transfusion is part of the treatment plan of many children and adolescents.
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Pediatric licensed care providers should have a basic understanding of different components, including storage conditions, indications and contraindications, and procedures for administration.
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The rationale and indications for product modifications are necessary to provide appropriate blood and blood components.
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Immunohematological testing is critically important in providing appropriate blood and blood components for children.
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The decision to transfuse should involve careful consideration of the risks versus benefits.
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