Characteristic
HCG trigger alone (n = 55)
Dual trigger (n = 52)
P value
Age at the time of the cycle (y)
38.36 ± 3.92
39.50 ± 3.05
0.10
Body mass index (kg/m2)
26.39 ± 5.21
25.99 ± 5.43
0.70
Anti-Mullerian hormone (ng/mL)
0.74 ± 0.76
0.97 ± 0.92
0.16
Total antral follicle count (n)
7.78 ± 3.79
7.83 ± 5.17
0.96
Characteristics and outcomes of ovarian stimulation (mean ± SD or % where applicable)
|
Variable |
HCG trigger alone (n = 55) |
Dual trigger (n = 52) |
P value |
|---|---|---|---|
|
Days of stimulation |
10.13 ± 1.29 |
10.98 ± 2.21 |
0.016 |
|
Total gonadotropins (IU) |
500.45 ± 138.49 |
600.96 ± 229.71 |
0.007 |
|
Total antagonist dose (vial) |
1.65 ± 0.89 |
2.66 ± 1.10 |
<0.001 |
|
Peak follicle size (mm) |
21.99 ± 3.77 |
20.27 ± 2.88 |
0.009 |
|
No of follicles ≥ 10 mm |
4.25 ± 1.97 |
3.81 ± 1.92 |
0.24 |
|
No of follicles ≥ 14 mm |
2.98 ± 1.41 |
2.81 ± 1.43 |
0.53 |
|
No follicles ≥ 16 mm |
2.31 ± 1.25 |
2.13 ± 1.11 |
0.45 |
|
Pre-trigger E2 (pg/mL) |
1082.56 ± 608.33 (n = 54) |
926.35 ± 455.47 |
0.14 |
|
Pre-trigger LH (IU/L) |
6.66 ± 4.23 (n = 54) |
5.60 ± 3.16 |
0.15 |
|
Pre-trigger P4 (ng/mL) |
0.54 ± 0.35 (n = 38) |
0.41 ± 0.21 |
0.033 |
|
No of oocytes |
2.69 ± 1.75 |
2.23 ± 1.35 |
0.10 |
|
No of MII |
2.16 ± 1.27 (n = 24) |
2.10 ± 1.27 (n = 42) |
0.83 |
|
No of 2PN fertilization |
2.09 ± 1.42 |
1.75 ± 1.33 |
0.20 |
|
ICSI (the remaining with conventional insemination) |
43.60% |
80.80% |
<0.001 |
|
No of day 3 embryos frozen |
1.57 ± 0.78 (n = 7) |
1.13 ± 0.84 (n:8) |
0.87 |
|
No of blastocyst stage embryos frozen |
1.15 ± 1.13 (n = 48) |
0.91 ± 1.18 (n:45)a |
0.187 |
|
Any embryo frozen |
67.27% |
51.92% |
0.12 |
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