Characteristic
HCG trigger alone (n = 55)
Dual trigger (n = 52)
P value
Age at the time of the cycle (y)
38.36 ± 3.92
39.50 ± 3.05
0.10
Body mass index (kg/m2)
26.39 ± 5.21
25.99 ± 5.43
0.70
Anti-Mullerian hormone (ng/mL)
0.74 ± 0.76
0.97 ± 0.92
0.16
Total antral follicle count (n)
7.78 ± 3.79
7.83 ± 5.17
0.96
Characteristics and outcomes of ovarian stimulation (mean ± SD or % where applicable)
Variable | HCG trigger alone (n = 55) | Dual trigger (n = 52) | P value |
---|---|---|---|
Days of stimulation | 10.13 ± 1.29 | 10.98 ± 2.21 | 0.016 |
Total gonadotropins (IU) | 500.45 ± 138.49 | 600.96 ± 229.71 | 0.007 |
Total antagonist dose (vial) | 1.65 ± 0.89 | 2.66 ± 1.10 | <0.001 |
Peak follicle size (mm) | 21.99 ± 3.77 | 20.27 ± 2.88 | 0.009 |
No of follicles ≥ 10 mm | 4.25 ± 1.97 | 3.81 ± 1.92 | 0.24 |
No of follicles ≥ 14 mm | 2.98 ± 1.41 | 2.81 ± 1.43 | 0.53 |
No follicles ≥ 16 mm | 2.31 ± 1.25 | 2.13 ± 1.11 | 0.45 |
Pre-trigger E2 (pg/mL) | 1082.56 ± 608.33 (n = 54) | 926.35 ± 455.47 | 0.14 |
Pre-trigger LH (IU/L) | 6.66 ± 4.23 (n = 54) | 5.60 ± 3.16 | 0.15 |
Pre-trigger P4 (ng/mL) | 0.54 ± 0.35 (n = 38) | 0.41 ± 0.21 | 0.033 |
No of oocytes | 2.69 ± 1.75 | 2.23 ± 1.35 | 0.10 |
No of MII | 2.16 ± 1.27 (n = 24) | 2.10 ± 1.27 (n = 42) | 0.83 |
No of 2PN fertilization | 2.09 ± 1.42 | 1.75 ± 1.33 | 0.20 |
ICSI (the remaining with conventional insemination) | 43.60% | 80.80% | <0.001 |
No of day 3 embryos frozen | 1.57 ± 0.78 (n = 7) | 1.13 ± 0.84 (n:8) | 0.87 |
No of blastocyst stage embryos frozen | 1.15 ± 1.13 (n = 48) | 0.91 ± 1.18 (n:45)a | 0.187 |
Any embryo frozen | 67.27% | 51.92% | 0.12 |