Adnexal Mass in Pregnancy
Karen Y. Oh, MD
DIFFERENTIAL DIAGNOSIS
Common
Corpus Luteum Cyst
Teratoma
Theca Lutein Cysts
Less Common
Other Ovarian Masses
Endometrioma
Cystadenoma
Epithelial Ovarian Carcinoma
Sex-Cord Stromal Tumor
Non-Ovarian Adnexal Masses
Paraovarian Cyst
Pedunculated Fibroid
Ectopic Pregnancy
Hydrosalpinx
Abscess
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
Adnexa should be routinely evaluated during pregnancy
Usually with transvaginal ultrasound in the first trimester
Identify and characterize ovaries
If not visible in pelvis, use transabdominal approach
Ovary can be displaced by large associated mass or torsion
If mass present, characterize as ovarian versus paraovarian in location
Ovarian mass
Cystic ovarian mass usually related to corpus luteum
Most often simple cyst of varying sizes
Can be complicated or even solid-appearing
If large, consider close follow-up and postpartum ultrasound to exclude benign ovarian tumor
Solid ovarian mass most often a dermoid
Should have classic appearance
May be bilateral
If ovarian mass is suspicious with cystic and solid components, consider removal during pregnancy
Paraovarian cysts will not change over time and may have been seen on prior pelvic ultrasounds
If in the right lower quadrant, assess for appendicitis/appendiceal abscess
Adnexal mass in 1st trimester
Could this be an ectopic or heterotopic pregnancy?
Correlate with any history of in vitro fertilization or reproductive assistance
Helpful Clues for Common Diagnoses
Corpus Luteum Cyst
May be anechoic or hemorrhagic
Commonly complicated by hemorrhage
Can have thick, vascular, hyperechoic cyst wall
May be mistaken for ectopic gestational sac with decidual reaction
Ovarian ectopic pregnancy is exceedingly rare
Should decrease in size over pregnancy
Some functional cysts may persist
Can follow expectantly if no malignant features
Postpartum pelvic ultrasound to exclude benign ovarian neoplasm
Check for any prior pelvic ultrasounds to see if present before pregnancy
Teratoma
Most common incidental ovarian mass seen in pregnancy
10% bilateral
May see hair, teeth, osseous structures which gives characteristic complex sonographic appearance
Dermoid plug often present
Echogenic keratin “plug”
Posterior acoustic shadowing
If large, risk of ovarian torsion
Theca Lutein Cysts
Multiple cysts within enlarged ovaries bilaterally
May see typical “spoke-wheel” appearance
Occasionally unilateral
Reaction of ovaries to elevated hormone levels
Multiple gestation pregnancies
Assisted reproduction patients
Rarely singleton pregnancy with underlying high level of beta hCG
Associated pregnancy may be abnormal
Molar pregnancy – partial or complete mole
Hydrops – skin edema, ascites, pleural effusions
Triploidy – multiple fetal anomalies, IUGR
Look for signs of hyperstimulation syndrome
Maternal effusions, ascites, oliguria
Seen in the setting of in vitro fertilization due to hormonal stimulation
May occur before intrauterine pregnancy identified
Helpful Clues for Less Common Diagnoses
Endometrioma
Homogeneous, low-level echoes
Cystadenoma
Serous – unilocular anechoic cyst, thin septations
Mucinous – hypoechoic with internal mucin, more often multilocular with thicker septations
Epithelial Ovarian Carcinoma
Complex cystic ovarian mass
Vascularized, thick, irregular septations with soft tissue masses
Look for ascites or other indications of peritoneal spread
Sex-Cord Stromal Tumor
Solid, homogeneous ovarian mass
May be hormonally active
Non-Ovarian Adnexal Masses
Paraovarian Cyst
Located in broad ligament
Does not change in size with hormonal fluctuationsStay updated, free articles. Join our Telegram channel
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