Abnormal Placental Cord Insertion
Roya Sohaey, MD
DIFFERENTIAL DIAGNOSIS
Common
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Marginal Cord Insertion
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Velamentous Cord Insertion (VCI)
Less Common
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Umbilical Cord Cyst
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Vasa Previa (VP)
Rare but Important
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Umbilical Cord Aneurysms
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
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Placental cord insertion (PCI) identification
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Easily achievable
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Seen in almost 100% 2nd trimester cases
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More difficult if posterior placenta and 3rd trimester fetus
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Use grayscale first
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Find general area of PCI
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Less motion artifact than Doppler
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Use color Doppler to confirm
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Rule out adjacent cord
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Show insertion and branching vessels
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All vessels should be on fetal surface of placenta
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Rule out submembranous vessels
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Use pulsed Doppler to show fetal flow
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Low resistive arterial flow
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Document fetal heart rate
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Look for PCI routinely in high risk cases
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Monochorionic twins
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Placenta previa
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Succenturiate lobe
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Abnormally large or small placenta
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Intrauterine growth restriction
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Anomalous fetus
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Use Doppler to make a specific diagnosis
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Look for submembranous vessels
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Velamentous cord
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Vasa previa
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Cyst versus aneurysm
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Identical appearance without color Doppler
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Use pulse Doppler
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Differentiate maternal from fetal vessels
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Helpful Clues for Common Diagnoses
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Marginal Cord Insertion
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PCI is within 2 cm of placental edge
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Good prognosis if isolated finding
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Sometimes associated with other placental abnormalities
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Small placenta
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Unusually thick placenta (Battledore)
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Monochorionic twinning
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Abruption
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Intrauterine growth restriction
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Progression to velamentous cord insertion
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Rare complication
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More likely if PCI is < 5 mm from margin
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Follow-up scans indicated
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Velamentous Cord Insertion (VCI)
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Membranous cord insertion
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VCI is often adjacent to placenta
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Some or all vessels are submembranous
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VCI may be seen between two placental lobes
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Atypical vessel appearance from lack of placental support
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Dilated vessels
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Excessively separated vessels
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Doppler essential for diagnosis
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Helps identify VCI
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Shows vessels extending from VCI to placenta
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Pulsed Doppler proves vessels are fetal
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Helpful Clues for Less Common Diagnoses
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Umbilical Cord Cyst
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33% of all UC cysts are at PCI
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Other 2/3 are mid cord or near fetus
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Often multiple and clustered at PCI
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PCI cysts are less likely to resolve
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First trimester UC cysts often resolve
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Rare complication includes intracystic hemorrhage
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May lead to cord compromise
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Rarely associated with fetal anomalies and aneuploidy
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Genitourinary anomalies
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Trisomy 18
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Amniocentesis probably not necessary if isolated finding in low risk patient
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Vasa Previa (VP)
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Submembranous fetal vessels near internal cervical os
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Within 2 cm of os considered VP
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VP from succenturiate lobe
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Vasa previa from VCI
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Low lying placenta with VCI
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Velamentous vessels near internal cervical os
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Prenatal diagnosis is imperative
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60-80% fetal mortality associated with missed diagnosis
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Fetal exsanguination with cervical dilatation
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Helpful Clues for Rare Diagnoses
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Umbilical Cord Aneurysms
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Umbilical artery (UA) aneurysm
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Most common location is at PCI
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Saccular dilatation of UA
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May have arteriovenous fistula to umbilical vein
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Associated with single umbilical artery, fetal anomalies and trisomy 18
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Best prognosis if isolated finding
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Umbilical vein (UV) varix
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Most common location is intraabdominal in fetus
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Rarely in free floating loops of cord
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Associated with increased venous pressure and hydrops
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Rarely can thrombose or rupture
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Other Essential Information
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Do not confuse VP with marginal sinus previa (MSP)
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MSP definition
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Low lying placenta
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Marginal placental vessels < 2 cm from internal cervical os
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MSP vessels are maternal
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Pulse Doppler shows placental venous flow
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No fetal arterial flow detectable
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Bleeding from MSP is maternal blood
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