The Healthy Newborn

Chapter 14 The Healthy Newborn









What Infectious Diseases Pose Risks to the Newborn?


Maternal infections may cause fetal or neonatal diseases, many of which can be treated or prevented by immunizations or prophylaxis (Table 14-1). HIV testing is now recommended for all pregnant women. Factors related to the risk of newborn infection include prematurity, prolonged rupture of membranes, maternal fever during labor, and chorioamnionitis. The mother’s group B streptococcus (GBS) status is important: To prevent transmission of GBS from a colonized mother to the newborn, National Institutes of Health (NIH) guidelines recommend that penicillin be administered to the mother at least 4 hours before birth. It is also important to note whether the mother received any other antibiotics during labor and why. For example, antibiotic prophylaxis may be given in labor for mitral valve prolapse.


Table 14-1 Maternal Infections That Can Affect the Newborn










































Organism Key Historical Information
Varicella-zoster Maternal and sibling history of disease or immunization. Active varicella in mother near term? Recent exposure by any nonimmune family members?
Herpes simplex I and II Genital herpes: frequency and treatment. Active lesions at the start of labor?
Rubella, measles, mumps Maternal immunization history or result of antibody screen
Hepatitis B History of maternal disease and mode of disease acquisition (IV drugs, multiple sexual partners). Current status of disease (active, carrier). Family tested, immunized?
HIV High-risk behaviors? Results of HIV testing, if done
Listeria Consumption of cold cuts, hot dogs, or unpasteurized cheese
Tuberculosis Immigrant from endemic country? BCG? History of contact or active disease? PPD status of mother and family members
Chlamydia High-risk behaviors. Other STDs?
Gonococcus High-risk behaviors. Other STDs?
Syphilis High-risk behaviors. RPR or VDRL status? Other STDs?
Toxoplasmosis History of exposure (cats, consumption or handling of raw meat or garden products)? Test results?
Group B streptococci Is mother colonized? Results of screening tests? Treatment history?

BCG, Bacille Calmette-Guérin; HIV, human immunodeficiency virus; IV, intravenous; PPD, purified protein derivative; RPR, rapid plasma reagin; STD, sexually transmitted disease; VDRL, Venereal Disease Research Laboratory.










What Transitional Issues Must I Consider?








< div class='tao-gold-member'>

Stay updated, free articles. Join our Telegram channel

Jun 19, 2016 | Posted by in PEDIATRICS | Comments Off on The Healthy Newborn

Full access? Get Clinical Tree

Get Clinical Tree app for offline access