54 PERIPHERAL NEUROPATHY General Discussion Peripheral neuropathy represents one of the most common neurologic disorders encountered by primary care physicians. Peripheral neuropathy may be the result of hereditary, toxic, infectious, inflammatory, metabolic, ischemic, or paraneoplastic causes. Diabetes and alcoholism are the most common etiologies of peripheral neuropathy in adults living in developed countries. Despite extensive evaluation, an etiology is not found in 13–22% of cases. Most patients can be diagnosed, classified, and managed based on the history and physical examination. Classifying the patient’s neuropathy clinically based upon time course (acute, subacute, chronic, or lifelong), functional modalities affected (motor or sensory) and the distribution (distal, proximal, or patchy) can assist in diagnosis. Other important information includes medication use, past medical history, age of onset, and family history. Medications Associated with Neuropathy Alfa interferon Amiodarone Amitriptyline Chloramphenicol Chloroquine Cimetidine Cisplatin Colchicine Dapsone Didanosine Dideoxycytidine Dideoxyinosine Disulfiram Docetaxel Ethambutol Gold Hydralazine Isoniazid Lithium Metronidazole Nitrofurantoin Nitrous oxide Paclitaxel Phenytoin Pyridoxine (vitamin B6) Simvastatin Suramin Thalidomide Vincristine Causes of Peripheral Neuropathy Acute pandysautonomia Alcoholism Amyloidosis Carcinomatous axonal sensorimotor polyneuropathy Chronic gluten enteropathy Chronic inflammatory demyelinating polyradiculopathy Crohn’s disease Churg–Strauss vasculitis Compressive neuropathies Critical illness polyneuropathy Cryoglobulinemia Diabetes mellitus Diphtheria Entrapment • Acromegaly • Amyloidosis Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA HAIR LOSS HYPOTHYROIDISM TRANSAMINASE ELEVATION Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on PERIPHERAL NEUROPATHY Full access? Get Clinical Tree
54 PERIPHERAL NEUROPATHY General Discussion Peripheral neuropathy represents one of the most common neurologic disorders encountered by primary care physicians. Peripheral neuropathy may be the result of hereditary, toxic, infectious, inflammatory, metabolic, ischemic, or paraneoplastic causes. Diabetes and alcoholism are the most common etiologies of peripheral neuropathy in adults living in developed countries. Despite extensive evaluation, an etiology is not found in 13–22% of cases. Most patients can be diagnosed, classified, and managed based on the history and physical examination. Classifying the patient’s neuropathy clinically based upon time course (acute, subacute, chronic, or lifelong), functional modalities affected (motor or sensory) and the distribution (distal, proximal, or patchy) can assist in diagnosis. Other important information includes medication use, past medical history, age of onset, and family history. Medications Associated with Neuropathy Alfa interferon Amiodarone Amitriptyline Chloramphenicol Chloroquine Cimetidine Cisplatin Colchicine Dapsone Didanosine Dideoxycytidine Dideoxyinosine Disulfiram Docetaxel Ethambutol Gold Hydralazine Isoniazid Lithium Metronidazole Nitrofurantoin Nitrous oxide Paclitaxel Phenytoin Pyridoxine (vitamin B6) Simvastatin Suramin Thalidomide Vincristine Causes of Peripheral Neuropathy Acute pandysautonomia Alcoholism Amyloidosis Carcinomatous axonal sensorimotor polyneuropathy Chronic gluten enteropathy Chronic inflammatory demyelinating polyradiculopathy Crohn’s disease Churg–Strauss vasculitis Compressive neuropathies Critical illness polyneuropathy Cryoglobulinemia Diabetes mellitus Diphtheria Entrapment • Acromegaly • Amyloidosis Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA HAIR LOSS HYPOTHYROIDISM TRANSAMINASE ELEVATION Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on PERIPHERAL NEUROPATHY Full access? Get Clinical Tree
