52 OSTEOPOROSIS General Discussion Primary osteoporosis results from deterioration of bone mass that is related to aging and decreased gonadal function but is not associated with any chronic illness. Because primary osteoporosis results from decreased gonadal function, early menopause or premenopausal estrogen deficiency may hasten the development of osteoporosis. Other risk factors for primary osteoporosis include female gender, white or Asian ancestry, sedentary lifestyle, tobacco use, low calcium intake, and low body weight. Secondary osteoporosis results from chronic conditions that contribute to accelerated bone density loss. Chronic conditions that may contribute to secondary osteoporosis include acromegaly, alcoholism, anorexia nervosa, chronic liver disease, diabetes mellitus type I, glycogen storage diseases, hemochromatosis, homocystinuria, hyperadrenocorticism, hyperparathyroidism, hyperprolactinemia, hypophosphatasia, malabsorption syndromes and gastric operations, Marfan syndrome, osteogenesis imperfecta, renal disease, thyrotoxicosis, and vitamin D deficiency. Long-term glucocorticoid therapy is a common cause of osteoporosis. A list of medications that may cause osteoporosis is listed below. Men are more likely than women to have a secondary cause of osteoporosis. In the patient with osteoporosis, initial evaluation should begin with a risk factor assessment (see risk factors below) and a history and physical examination focusing on signs of chronic disease. If secondary osteoporosis is suspected based upon findings from the history and physical examination, a work-up should be performed. Medications Associated with Osteoporosis Cyclosporine Furosemide Glucocorticoids GnRH agonists Heparin (prolonged treatment) Methotrexate Phenobarbital Phenothiazines Phenytoin Thyroid hormone excess Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA HAIR LOSS HYPOTHYROIDISM SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on OSTEOPOROSIS Full access? Get Clinical Tree
52 OSTEOPOROSIS General Discussion Primary osteoporosis results from deterioration of bone mass that is related to aging and decreased gonadal function but is not associated with any chronic illness. Because primary osteoporosis results from decreased gonadal function, early menopause or premenopausal estrogen deficiency may hasten the development of osteoporosis. Other risk factors for primary osteoporosis include female gender, white or Asian ancestry, sedentary lifestyle, tobacco use, low calcium intake, and low body weight. Secondary osteoporosis results from chronic conditions that contribute to accelerated bone density loss. Chronic conditions that may contribute to secondary osteoporosis include acromegaly, alcoholism, anorexia nervosa, chronic liver disease, diabetes mellitus type I, glycogen storage diseases, hemochromatosis, homocystinuria, hyperadrenocorticism, hyperparathyroidism, hyperprolactinemia, hypophosphatasia, malabsorption syndromes and gastric operations, Marfan syndrome, osteogenesis imperfecta, renal disease, thyrotoxicosis, and vitamin D deficiency. Long-term glucocorticoid therapy is a common cause of osteoporosis. A list of medications that may cause osteoporosis is listed below. Men are more likely than women to have a secondary cause of osteoporosis. In the patient with osteoporosis, initial evaluation should begin with a risk factor assessment (see risk factors below) and a history and physical examination focusing on signs of chronic disease. If secondary osteoporosis is suspected based upon findings from the history and physical examination, a work-up should be performed. Medications Associated with Osteoporosis Cyclosporine Furosemide Glucocorticoids GnRH agonists Heparin (prolonged treatment) Methotrexate Phenobarbital Phenothiazines Phenytoin Thyroid hormone excess Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA HAIR LOSS HYPOTHYROIDISM SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on OSTEOPOROSIS Full access? Get Clinical Tree
