(1)
Medical School, University of Porto, Porto, Portugal
7.1 Definition, Incidence and Main Risk Factors
Maternal cardiorespiratory arrest is estimated to occur in 0.003 % of pregnancies and manifests by loss of consciousness and central cyanosis. There are a number of possible aetiologies for this event (Table 7.1), but in high-resource countries, pulmonary thromboembolism and amniotic fluid embolism are among the leading causes. A detailed description of the maternal conditions that may lead to cardiorespiratory arrest is beyond the aim of this book, so this chapter will focus on the acute management of the situation and the initial treatment of the two most frequent causes.
Table 7.1
Major causes of maternal cardiorespiratory arrest
Obstetric complications | Major obstetric haemorrhage (abruption, uterine rupture, postpartum haemorrhage) |
Amniotic fluid embolism | |
Anaesthetic complications | High spinal anaesthesia |
Pulmonary aspiration of gastric contents | |
Toxicity of local anaesthetic agents | |
Medical complications | Pulmonary thromboembolism |
Myocardial infarction | |
Aortic dissection | |
Peripartum cardiomyopathy | |
Anaphylaxis | |
Sepsis/septic shock | |
Air embolus |
7.2 Consequences
Maternal cardiorespiratory arrest is associated with a high incidence of maternal deaths and long–term neurological sequelae. It is also associated with important perinatal mortality and long–term neurological sequelae for the child. Anticipation of the problem and early recognition allow prompt resuscitation and other support measures that have a profound impact on maternal and fetal prognosis.
7.3 Diagnosis
Maternal cardiorespiratory arrest manifests by loss of consciousness and central cyanosis. Absence of respiratory movements and lack of a carotid pulse confirm the diagnosis. The maternal electrocardiogram may display a continuous line representing asystole, or there may be ventricular fibrillation, ventricular tachycardia or any other type of electric activity without a carotid pulse.
7.4 Clinical Management
Whatever the cause of maternal cardiorespiratory arrest, the initial response is similar and involves the support of maternal oxygenation and circulation and rapid delivery of the fetus if the situation does not revert within 4 min. When both an anaesthetist and an obstetrician are present, the responsibility for these two aspects is usually divided among them. In the remaining cases, the most senior healthcare professional needs to take charge of the whole situation. Management of cardiorespiratory arrest occurring after delivery does not differ significantly from that occurring in the non-pregnant woman and is beyond the aim of this chapter.
7.4.1 Anticipating the Situation
The occurrence of sudden maternal shortness of breath (dyspnoea and tachypnoea) associated with central cyanosis suggests a serious respiratory complication that may be followed by cardiorespiratory arrest. When such symptoms occur, the woman should be placed in left lateral safety position (Fig. 7.1), and several of the aspects considered below can be anticipated, including maternal and fetal monitoring, vein catheterisation, summoning of appropriate staff and collection of equipment that may later be required (emergency trolley).
Fig. 7.1
Left lateral safety position
7.4.2 Clearly Verbalising the Diagnosis
It is important that all members of the healthcare team are aware of the diagnosis of maternal cardiorespiratory arrest, and therefore this needs to be clearly verbalised.
7.4.3 Asking for Help
One of the first measures should be to summon urgently at least two midwives, a senior obstetrician, an anaesthetist and the hospital resuscitation team. As stated above, the presence of an anaesthetist guarantees a safer management of respiratory and circulatory functions, as well as basic fluid balance. Care is however needed to maintain good communication between both sides at all times, so that there is coordinated management of the situation.
7.4.4 Maternal Monitoring
When cardiorespiratory arrest occurs in a hospital environment, maternal monitoring is a priority for objective assessment and response to treatment, so continuous evaluation of heart rate, oxygen saturation and electrocardiography should be started promptly and the blood pressure measured at least every 5–10 min.
7.4.5 Support of Maternal Oxygenation and Circulation
7.4.5.1 A (Airway): Guarantee the Patency of the Airway
To guarantee the patency of the airway, the patient should be turned onto her back, the head tilted backwards, the chin lifted and the mouth opened and inspected for objects that may cause obstruction. Secretions may be aspirated if abundant and a Mayo tube temporarily introduced to prevent the tongue from occluding the airway, if endotracheal intubation cannot be immediately performed.
7.4.5.2 B (Breathing): Maintain Oxygen Supply to the Lungs
To maintain oxygen supply to the lungs, ventilation with a bag–valve mask should be immediately started at 15 cycles/min, using 100 % oxygen and 15 l/min, and thereafter adapting according to oxygen saturation levels, which should be kept over 90 %. After obtaining the necessary material, early endotracheal intubation should be performed to improve the efficacy of ventilation and prevent aspiration of gastric contents. The ventilation cycles described above are maintained. If available, capnography should be used to confirm correct tube placement, as well as the adequacy of ventilation and cardiac massage. Pulmonary auscultation is necessary to evaluate proper endotracheal tube placement and the presence of additional respiratory sounds. As soon as possible, arterial blood gas sampling should be performed to evaluate whether the objective of maintaining partial pressure of oxygen above 60 mmHg is being achieved.
7.4.5.3 C (Circulation): Cardiac Massage and Vein Catheterisation
With maternal loss of consciousness and an absent carotid pulse, immediate external cardiac massage should be started, independently of whether or not cardiac activity is detected on the electrocardiogram. A hard board should be placed underneath the woman, and if pregnancy is above 20 weeks, a hard object is placed under this board to create a 30° left tilt (Fig. 7.2 – left). The objective is to avoid aorto-caval compression by the pregnant uterus and the resulting decreased venous return from the lower limbs. If this is not immediately available, an alternative is to shift the abdomen laterally and displace the uterus to the left (Fig. 7.2 – centre).
Fig. 7.2
Hard board and 30° left tilt (left), left lateral abdominal displacement (centre), positioning of the body and hands for external cardiac massage (right)
Cardiac massage is performed by placing two interlocked hands on the inferior portion of the patient’s sternum and with the arms fully stretched, applying rhythmic compressions at 100 cycles per minute, depressing the sternum by about 5 cm (Fig. 7.2 – right). There is ample evidence that appropriately applied cardiac massage causes respiratory movements, so this should be the prioritised manoeuvre if no one is available to guarantee ventilation. Cardiac massage is only stopped for brief seconds every 2 min, to re-evaluate cardiac rhythm and the carotid pulse. The procedure is only abandoned when an adequate cardiac rhythm and pulse are detected, or when death is declared.