40 HYPOGLYCEMIA General Discussion Symptoms of hypoglycemia begin at plasma glucose levels of approximately 60 mg/dL, and impairment of nervous system function begins at approximately 50 mg/dL. Clinical hypoglycemia is identified by modified Whipple’s criteria: (1) CNS symptoms, including confusion, aberrant behavior, or coma; (2) a simultaneous blood glucose level equal to or less than 40 mg/dL; and (3) relief of these symptoms by the administration of glucose. The causes of hypoglycemia may be categorized into three main groups for the purposes of evaluation. These categories are medication- or toxin-induced hypoglycemia, disorders associated with fasting hypoglycemia, and disorders associated with postprandial hypoglycemia. Each of these categories is outlined in detail below. The list of medications associated with hypoglycemia is also listed below. Four simultaneous criteria should be present to establish the diagnosis of insulinoma: 1. Blood glucose less than 40 mg/dL 2. Symptoms of neuroglycopenia 3. Plasma insulin greater than 5 muU/mL 4. Plasma C-peptide greater than 0.6 ng/mL Medications Associated with Hypoglycemia ACE inhibitors Acetazolamide Acetohexamide Aspirin Azapropazone Benzodiazepines Buformin Carbutamide Chloroquine Chlorpromazine Chlorpropamide Cibenzoline Cimetidine Ciprofloxacin Clipizide Cycloheptolamide Dicumarol Diphenhydramine Disopyramide Doxepin Ecstasy (MDMA) Enflurane Ethionamide Etomidate Fenoterol Fluoxetine Formestane Furosemide Glibenclamide Gliclazide Glipizide Glyburide Haloperidol Halothane Herbal extracts Imipramine Indomethacin Insulin Interferon-α Isoniazid Isoxsuprine Lidocaine Lithium Maprotiline Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA HAIR LOSS INFERTILITY, MALE SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on HYPOGLYCEMIA Full access? Get Clinical Tree
40 HYPOGLYCEMIA General Discussion Symptoms of hypoglycemia begin at plasma glucose levels of approximately 60 mg/dL, and impairment of nervous system function begins at approximately 50 mg/dL. Clinical hypoglycemia is identified by modified Whipple’s criteria: (1) CNS symptoms, including confusion, aberrant behavior, or coma; (2) a simultaneous blood glucose level equal to or less than 40 mg/dL; and (3) relief of these symptoms by the administration of glucose. The causes of hypoglycemia may be categorized into three main groups for the purposes of evaluation. These categories are medication- or toxin-induced hypoglycemia, disorders associated with fasting hypoglycemia, and disorders associated with postprandial hypoglycemia. Each of these categories is outlined in detail below. The list of medications associated with hypoglycemia is also listed below. Four simultaneous criteria should be present to establish the diagnosis of insulinoma: 1. Blood glucose less than 40 mg/dL 2. Symptoms of neuroglycopenia 3. Plasma insulin greater than 5 muU/mL 4. Plasma C-peptide greater than 0.6 ng/mL Medications Associated with Hypoglycemia ACE inhibitors Acetazolamide Acetohexamide Aspirin Azapropazone Benzodiazepines Buformin Carbutamide Chloroquine Chlorpromazine Chlorpropamide Cibenzoline Cimetidine Ciprofloxacin Clipizide Cycloheptolamide Dicumarol Diphenhydramine Disopyramide Doxepin Ecstasy (MDMA) Enflurane Ethionamide Etomidate Fenoterol Fluoxetine Formestane Furosemide Glibenclamide Gliclazide Glipizide Glyburide Haloperidol Halothane Herbal extracts Imipramine Indomethacin Insulin Interferon-α Isoniazid Isoxsuprine Lidocaine Lithium Maprotiline Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA HAIR LOSS INFERTILITY, MALE SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on HYPOGLYCEMIA Full access? Get Clinical Tree
