35 HYPERCOAGULABLE STATES General Discussion Hypercoagulable conditions are classified as primary (an inherited condition) or secondary (an acquired state). The inherited disorders include factor V Leiden, prothrombin G20210A gene mutation, hyperhomocysteinemia, elevated factor VIII level, and the deficiencies of antithrombin, protein C, and protein S. Acquired hypercoagulable conditions include the antiphospholipid syndrome (lupus anticoagulant and anticardiolipin antibody), hyperhomocysteinemia, and the commonly known thrombosis risk factors of pregnancy, cancer, and estrogen-containing medications. There is no standardized approach to screening patients for hypercoagulability. The cost-effectiveness of performing the laboratory examination is unknown, and the work-up typically is expensive. Most clinicians take into consideration patient risk factors when deciding upon the need for an extensive work-up. Any one of the following indicators typically calls for further evaluation: thrombosis at a young age (less than 50 years), family history of thrombosis, recurrent thrombosis, idiopathic thrombosis, and thrombosis at an unusual site such as mesenteric, cerebral, or portal veins. Risk Factors for Venous Thrombosis Previous venous thromboembolism Inherited or acquired thrombophilias Surgical and nonsurgical trauma Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA HAIR LOSS INFERTILITY, MALE SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on HYPERCOAGULABLE STATES Full access? Get Clinical Tree
35 HYPERCOAGULABLE STATES General Discussion Hypercoagulable conditions are classified as primary (an inherited condition) or secondary (an acquired state). The inherited disorders include factor V Leiden, prothrombin G20210A gene mutation, hyperhomocysteinemia, elevated factor VIII level, and the deficiencies of antithrombin, protein C, and protein S. Acquired hypercoagulable conditions include the antiphospholipid syndrome (lupus anticoagulant and anticardiolipin antibody), hyperhomocysteinemia, and the commonly known thrombosis risk factors of pregnancy, cancer, and estrogen-containing medications. There is no standardized approach to screening patients for hypercoagulability. The cost-effectiveness of performing the laboratory examination is unknown, and the work-up typically is expensive. Most clinicians take into consideration patient risk factors when deciding upon the need for an extensive work-up. Any one of the following indicators typically calls for further evaluation: thrombosis at a young age (less than 50 years), family history of thrombosis, recurrent thrombosis, idiopathic thrombosis, and thrombosis at an unusual site such as mesenteric, cerebral, or portal veins. Risk Factors for Venous Thrombosis Previous venous thromboembolism Inherited or acquired thrombophilias Surgical and nonsurgical trauma Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA HAIR LOSS INFERTILITY, MALE SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on HYPERCOAGULABLE STATES Full access? Get Clinical Tree
