Hemolytic Disease, ABO Incompatibility
Basic Information
Definition
Hemolytic disease with ABO incompatibility is hemolysis of neonatal red blood cells (RBCs) secondary to incompatibility between a type O mother and a type A or B newborn.
Epidemiology & Demographics
• In one large series, 28% of ABO-incompatible babies had a weakly positive direct Coombs test and only 2% of these required an exchange transfusion.
