Dysgerminoma

Chapter 126 Dysgerminoma



INTRODUCTION



Description: A dysgerminoma is an ovarian tumor made up of germ cells and stroma that appears analogous in structure to the seminomas found in the male testes. Although rare, these tumors are the most common malignant germ cell tumors.

Prevalence: Rare, 1% to 2% of ovarian malignancies.

Predominant Age: Older than 30 (10% in prepubertal girls).

Genetics: No genetic pattern.


ETIOLOGY AND PATHOGENESIS



Causes: Unknown. (May differentiate from primitive germ cells.)

Risk Factors: None known.


CLINICAL CHARACTERISTICS



Signs and Symptoms



• Asymptomatic

• Adnexal mass (bilateral in 5% to 10%), lobulated, solid and soft or firm, with a gray–white or cream-colored cut surface.


DIAGNOSTIC APPROACH



Differential Diagnosis



• Benign adnexal masses (corpus luteum, follicular cyst)

• Endometriosis

• Hydrosalpinx

• Paratubal cyst

• Appendiceal abscess

• Ectopic pregnancy

• Pedunculated leiomyomata

• Pelvic or horseshoe kidney

• Nongynecologic pelvic masses


Associated Conditions: None.


WORKUP AND EVALUATION



Laboratory:

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Jun 6, 2016 | Posted by in GYNECOLOGY | Comments Off on Dysgerminoma

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