Dysgerminoma

Chapter 126 Dysgerminoma

INTRODUCTION

Description: A dysgerminoma is an ovarian tumor made up of germ cells and stroma that appears analogous in structure to the seminomas found in the male testes. Although rare, these tumors are the most common malignant germ cell tumors.
Prevalence: Rare, 1% to 2% of ovarian malignancies.
Predominant Age: Older than 30 (10% in prepubertal girls).
Genetics: No genetic pattern.

ETIOLOGY AND PATHOGENESIS

Causes: Unknown. (May differentiate from primitive germ cells.)
Risk Factors: None known.

CLINICAL CHARACTERISTICS

Signs and Symptoms

• Asymptomatic
• Adnexal mass (bilateral in 5% to 10%), lobulated, solid and soft or firm, with a gray–white or cream-colored cut surface.

DIAGNOSTIC APPROACH

Differential Diagnosis

• Benign adnexal masses (corpus luteum, follicular cyst)
• Endometriosis
• Hydrosalpinx
• Paratubal cyst
• Appendiceal abscess
• Ectopic pregnancy
• Pedunculated leiomyomata
• Pelvic or horseshoe kidney
• Nongynecologic pelvic masses

Associated Conditions: None.

WORKUP AND EVALUATION

Laboratory:

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Jun 6, 2016 | Posted by in GYNECOLOGY | Comments Off on Dysgerminoma

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