Chapter 19 Diverticular Disease
INTRODUCTION
Description: Diverticular disease involves herniation of the colon mucosa through the muscular wall. These herniations are most common in the sigmoid and distal colon, increase in prevalence with age, and can lead to significant morbidity when rupture or abscess formation occurs. Diverticulosis is the presence of these herniations, whereas diverticulitis is the symptomatic state.
ETIOLOGY AND PATHOGENESIS
Causes: Speculative, not clearly established. Proposed—defect in colon motility with increased intraluminal pressure, exacerbated by a low-fiber diet or an intrinsic defect in the colon wall.