CHAPTER 12 Common drugs and infusions Mark Davies, David Cartwright Common drug doses • Aminophylline (IV) or theophylline (oral/NG) — loading……5 mg/kg — maintenance…2 mg/kg/dose…every 8 hours • Ampicillin (IV)…50 mg/kg/dose…every 12 hours • Caffeine citrate (IV/oral/NG) — loading…20 mg/kg — maintenance…5–10 mg/kg/dose…daily • Cefotaxime (IV)…50 mg/kg/dose…every 12 hours • Chloral hydrate (oral/NG) — hypnotic…50 mg/kg/dose…STAT — sedation…6 mg/kg/dose…every 6 hours • Dexamethasone…see pages 86–8 • Iron (oral/NG)…see page 76 • Flucloxacillin (IV)…50 mg/kg/dose — first week of life…every 12 hours — 2–4 weeks old…every 8 hours — >4 weeks old…every 6 hours • Frusemide (IV/oral/NG)…1–2 mg/kg/dose…every 12 hours • Gentamicin (IV)…2.5 mg/kg/dose — <30 weeks…every 36 hours — ≥30 weeks…daily — trough level, prior to third dose, <2 mg/L is OK • Hydrocortisone (IV)…1–2.5 mg/kg…every 4–6 hours initially • Indomethacin (IV) — a number of regimens exist: — prophylaxis…0.1 mg/kg/dose…daily for 3 days — treatment #1 (usual)…0.1 mg/kg/dose…daily for 6 days — treatment #2…0.2 mg/kg/dose…every 12 hours for 3 doses — treatment #3…0.2 mg/kg STAT…then 2 doses of 0.1 mg/kg…every 12 hours — treatment #4…0.2 mg/kg/dose every 12 hours for 3 doses…then 0.1 mg/kg/dose daily for 4 or 5 days • Midazolam (IV)…50–100 μg/kg/dose (i.e. 0.05–0.1 mg/kg) • Morphine (IV)…50–100 μg/kg/dose (i.e. 0.05–0.1 mg/kg) • Penicillin (IV)…60 mg/kg/dose… every 12 hours • Phenobarbitone (IV/oral/NG) — loading…20–30 mg/kg/dose — further bolus…10 mg/kg/dose — maintenance…2.5 mg/kg/dose…every 12 hours • Phosphate (NG)…see page 76 • Ranitidine (oral/NG)…3–6 mg/kg/dose…every 8 hours • Spironolactone (oral/NG)…1–2 mg/kg/dose…every 12 hours • Theophylline see aminophylline • Vancomycin (IV)…15 mg/kg/dose — <1200 g…every 24 hours Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Fluids and nutrition Cranial ultrasounds Maternal thyroid disease Withdrawal of treatment Stay updated, free articles. Join our Telegram channel Join Tags: Pocket Notes on Neonatology Jul 18, 2016 | Posted by admin in PEDIATRICS | Comments Off on Common drugs and infusions Full access? Get Clinical Tree
CHAPTER 12 Common drugs and infusions Mark Davies, David Cartwright Common drug doses • Aminophylline (IV) or theophylline (oral/NG) — loading……5 mg/kg — maintenance…2 mg/kg/dose…every 8 hours • Ampicillin (IV)…50 mg/kg/dose…every 12 hours • Caffeine citrate (IV/oral/NG) — loading…20 mg/kg — maintenance…5–10 mg/kg/dose…daily • Cefotaxime (IV)…50 mg/kg/dose…every 12 hours • Chloral hydrate (oral/NG) — hypnotic…50 mg/kg/dose…STAT — sedation…6 mg/kg/dose…every 6 hours • Dexamethasone…see pages 86–8 • Iron (oral/NG)…see page 76 • Flucloxacillin (IV)…50 mg/kg/dose — first week of life…every 12 hours — 2–4 weeks old…every 8 hours — >4 weeks old…every 6 hours • Frusemide (IV/oral/NG)…1–2 mg/kg/dose…every 12 hours • Gentamicin (IV)…2.5 mg/kg/dose — <30 weeks…every 36 hours — ≥30 weeks…daily — trough level, prior to third dose, <2 mg/L is OK • Hydrocortisone (IV)…1–2.5 mg/kg…every 4–6 hours initially • Indomethacin (IV) — a number of regimens exist: — prophylaxis…0.1 mg/kg/dose…daily for 3 days — treatment #1 (usual)…0.1 mg/kg/dose…daily for 6 days — treatment #2…0.2 mg/kg/dose…every 12 hours for 3 doses — treatment #3…0.2 mg/kg STAT…then 2 doses of 0.1 mg/kg…every 12 hours — treatment #4…0.2 mg/kg/dose every 12 hours for 3 doses…then 0.1 mg/kg/dose daily for 4 or 5 days • Midazolam (IV)…50–100 μg/kg/dose (i.e. 0.05–0.1 mg/kg) • Morphine (IV)…50–100 μg/kg/dose (i.e. 0.05–0.1 mg/kg) • Penicillin (IV)…60 mg/kg/dose… every 12 hours • Phenobarbitone (IV/oral/NG) — loading…20–30 mg/kg/dose — further bolus…10 mg/kg/dose — maintenance…2.5 mg/kg/dose…every 12 hours • Phosphate (NG)…see page 76 • Ranitidine (oral/NG)…3–6 mg/kg/dose…every 8 hours • Spironolactone (oral/NG)…1–2 mg/kg/dose…every 12 hours • Theophylline see aminophylline • Vancomycin (IV)…15 mg/kg/dose — <1200 g…every 24 hours Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Fluids and nutrition Cranial ultrasounds Maternal thyroid disease Withdrawal of treatment Stay updated, free articles. Join our Telegram channel Join
