9 BLEEDING AND BRUISING General Discussion Abnormal bleeding or bruising may cause significant anxiety for the patient and may be a sign of a serious inherited or acquired disorder. A history of bleeding following dental extraction, minor surgery, or childbirth suggests an underlying hemostatic disorder. Bleeding that is severe enough to require a blood transfusion merits particular attention. A family history of bleeding abnormalities suggests an inherited systemic disorder such as von Willebrand disease. Bleeding from a platelet disorder typically is localized to superficial sites such as the skin or mucous membranes and usually is easily controlled. However, bleeding from hemostatic or plasma coagulation defects may occur hours or days after injury and is difficult to control with local measures. This type of bleeding often occurs into muscles, joints, or body cavities. A thorough history is the most important step in establishing the presence of a hemostatic disorder and in guiding initial laboratory testing. Medications Associated with Bleeding Abciximab Aspirin Chemotherapeutic agents Clopidogrel Dalteparin Enoxaparin Eptifibatide Heparin Nonsteroidal anti-inflammatory drugs Phenytoin Quinine Recombinant t-Pas (Activase and Retavase) Ticlopidine Tinzaparin Tirofiban Urokinase Warfarin Causes of Bleeding Acquired factor VIII inhibitors Acute leukemia Adenocarcinoma Alpha2-antiplasmin deficiency Aplastic anemia Bernard-Soulier disease Bone marrow failure Chronic renal failure Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA GYNECOMASTIA INFERTILITY, MALE SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on BLEEDING AND BRUISING Full access? Get Clinical Tree
9 BLEEDING AND BRUISING General Discussion Abnormal bleeding or bruising may cause significant anxiety for the patient and may be a sign of a serious inherited or acquired disorder. A history of bleeding following dental extraction, minor surgery, or childbirth suggests an underlying hemostatic disorder. Bleeding that is severe enough to require a blood transfusion merits particular attention. A family history of bleeding abnormalities suggests an inherited systemic disorder such as von Willebrand disease. Bleeding from a platelet disorder typically is localized to superficial sites such as the skin or mucous membranes and usually is easily controlled. However, bleeding from hemostatic or plasma coagulation defects may occur hours or days after injury and is difficult to control with local measures. This type of bleeding often occurs into muscles, joints, or body cavities. A thorough history is the most important step in establishing the presence of a hemostatic disorder and in guiding initial laboratory testing. Medications Associated with Bleeding Abciximab Aspirin Chemotherapeutic agents Clopidogrel Dalteparin Enoxaparin Eptifibatide Heparin Nonsteroidal anti-inflammatory drugs Phenytoin Quinine Recombinant t-Pas (Activase and Retavase) Ticlopidine Tinzaparin Tirofiban Urokinase Warfarin Causes of Bleeding Acquired factor VIII inhibitors Acute leukemia Adenocarcinoma Alpha2-antiplasmin deficiency Aplastic anemia Bernard-Soulier disease Bone marrow failure Chronic renal failure Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: ARTHRITIS AND ARTHRALGIA GYNECOMASTIA INFERTILITY, MALE SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on BLEEDING AND BRUISING Full access? Get Clinical Tree
