6 ARTHRITIS AND ARTHRALGIA General Discussion Several different terms are often used to describe joint disorders resulting in joint pain. Arthralgia means joint pain. Arthritis implies the presence of an inflammatory component to the disorder. Arthropathy is a general term meaning joint disease but usually means that there is some degree of cartilage damage. Rheumatoid disease, infection, and crystal deposition are examples of conditions which produce an inflammatory response and a resultant cartilage loss. Osteoarthritis, or degenerative joint disease, occurs primarily as a result of cartilage breakdown, but often has a component of secondary inflammation. This chapter focuses on arthritis; however, some of the medications and conditions listed below may cause arthralgia without an inflammatory process. Before attributing a patient’s pain to arthritis, the physician must consider other potential causes of the pain. These potential diagnoses include intra-articular processes distinct from arthritis (impingement, neoplasm) as well as periarticular sources of pain (bursitis, tendonitis). Patients may also have referred pain from an adjacent site or a distant site as occurs with radiculopathy and spinal stenosis. Medications Associated with Arthritis/Arthralgias Acyclovir Adalimumab Amiodarone Amphotericin Atorvastatin Beta blockers Bacille Calmette–Guérin (BCG) vaccine Carbamazepine Chlorpromazine Cyclosporine Diuretics Erythropoietin Estrogens Etanercept Ethambutol Fibrates Fluoride Granulocyte-colony stimulating factor (G-CSF) Gold salts Griseofulvin Hydralazine Infliximab Interferons Interleukin-2 and interleukin-6 Isoniazid Letrozole Levodopa Lithium Methimazole Methyldopa Minocycline Nicardipine Nicotinic acid Para-aminosalicylic acid Penicillin Penicillamine Phenytoin Procainamide Propylthiouracil Pyrazinamide Quinidine Quinolones Raloxifene Reserpine Simvastatin Steroids (systemic) Sulfasalazine Tacrolimus Tamoxifen Terbinafine Tetracycline Ticlopidine Vitamin A excess Causes of Arthritis Ankylosing spondylitis Degenerative joint disease (osteoarthritis) Giant cell arteritis Gout Hemochromatosis Hemophilia Infection • Atypical mycobacteria • Bacterial (Staphylococcus aureus, Streptococcus, Salmonella, Neisseria gonorrhoeae, Haemophilus influenza, Escherichia coli, Pseudomonas) Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: BLEEDING AND BRUISING GYNECOMASTIA INFERTILITY, MALE SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on ARTHRITIS AND ARTHRALGIA Full access? Get Clinical Tree
6 ARTHRITIS AND ARTHRALGIA General Discussion Several different terms are often used to describe joint disorders resulting in joint pain. Arthralgia means joint pain. Arthritis implies the presence of an inflammatory component to the disorder. Arthropathy is a general term meaning joint disease but usually means that there is some degree of cartilage damage. Rheumatoid disease, infection, and crystal deposition are examples of conditions which produce an inflammatory response and a resultant cartilage loss. Osteoarthritis, or degenerative joint disease, occurs primarily as a result of cartilage breakdown, but often has a component of secondary inflammation. This chapter focuses on arthritis; however, some of the medications and conditions listed below may cause arthralgia without an inflammatory process. Before attributing a patient’s pain to arthritis, the physician must consider other potential causes of the pain. These potential diagnoses include intra-articular processes distinct from arthritis (impingement, neoplasm) as well as periarticular sources of pain (bursitis, tendonitis). Patients may also have referred pain from an adjacent site or a distant site as occurs with radiculopathy and spinal stenosis. Medications Associated with Arthritis/Arthralgias Acyclovir Adalimumab Amiodarone Amphotericin Atorvastatin Beta blockers Bacille Calmette–Guérin (BCG) vaccine Carbamazepine Chlorpromazine Cyclosporine Diuretics Erythropoietin Estrogens Etanercept Ethambutol Fibrates Fluoride Granulocyte-colony stimulating factor (G-CSF) Gold salts Griseofulvin Hydralazine Infliximab Interferons Interleukin-2 and interleukin-6 Isoniazid Letrozole Levodopa Lithium Methimazole Methyldopa Minocycline Nicardipine Nicotinic acid Para-aminosalicylic acid Penicillin Penicillamine Phenytoin Procainamide Propylthiouracil Pyrazinamide Quinidine Quinolones Raloxifene Reserpine Simvastatin Steroids (systemic) Sulfasalazine Tacrolimus Tamoxifen Terbinafine Tetracycline Ticlopidine Vitamin A excess Causes of Arthritis Ankylosing spondylitis Degenerative joint disease (osteoarthritis) Giant cell arteritis Gout Hemochromatosis Hemophilia Infection • Atypical mycobacteria • Bacterial (Staphylococcus aureus, Streptococcus, Salmonella, Neisseria gonorrhoeae, Haemophilus influenza, Escherichia coli, Pseudomonas) Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: BLEEDING AND BRUISING GYNECOMASTIA INFERTILITY, MALE SYNCOPE Stay updated, free articles. Join our Telegram channel Join Tags: Instant Work-ups A Clinical Guide to Medicine Aug 17, 2016 | Posted by admin in PEDIATRICS | Comments Off on ARTHRITIS AND ARTHRALGIA Full access? Get Clinical Tree
